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Method for preparing radix astragali extract at room temperature

A technology of astragalus extract and room temperature, which is applied in the field of preparation of astragalus extract at room temperature, can solve the problems that bacteria cannot be killed, the structure is destroyed, and the industrialization cost is high, and the possibility of being oxidized and volatilized is small, and the amount of bacteria is reduced. The probability of oxidation and the effect of improving the utilization rate

Inactive Publication Date: 2019-01-18
JIANGSU XINGYE POLYMERIZATION CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional decoction extraction process is: after the Chinese medicinal materials are picked, they are washed, dried, sliced, and then boiled with water, which takes a long time and produces a large amount of waste residue. The waste residue of medicinal materials needs to be landfilled, which is not conducive to environmental protection
[0004] With the penetration of modern medicine in the field of traditional Chinese medicine and the success of artemisinin, people have realized that the traditional decoction method, solvent ultrasonic extraction, etc. may not be the best solution, because during the decoction process, many For components such as volatile oil, many unstable structures are also destroyed during the decoction process at 60°C to 100°C, and ultrasonic extraction requires a solvent
In the prior art, chemical methods are also used to extract the active ingredients of traditional Chinese medicine, but there are disadvantages such as unfavorable to environmental protection, high energy consumption, long process flow, time-consuming labor, and high industrialization cost.
[0005] In order to solve the defects of high-temperature cooking and extraction, a normal-temperature extraction process has also appeared, but the existing normal-temperature extraction process does not have a high-temperature cooking process, so that bacteria cannot be killed, and there are potential safety hazards; and the existing normal-temperature extraction process has no active substances Small, difficult to be extracted in water, usually need to use organic solvent to extract, add catalyst, modifier, etc. high production cost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The device used is an infrared plasma surface modification device, which includes a vacuum pumping device and a sealed casing, and an ultrasonic tank, an infrared emitting device and a plasma generating device are arranged in the casing, and the infrared emitting device and the plasma generating device The devices are all set above the ultrasonic tank.

[0024] The preparation method of astragalus extract is as follows:

[0025] (1) Grinding: fresh astragalus is dried at 70°C for 4 hours and then put into a clean high-speed grinder (equipment manufacturer: Jiangsu Dongsheng Machinery Co., Ltd., model is FS300, the same below), after starting, grind for 20 seconds After taking out 1 kg, add it to the ultrasonic tank body of the above-mentioned infrared plasma surface modification device, put 5Kg of pure water in the tank, and add the nanoscale particles of astragaloside IV and acteosin glucoside simultaneously, and the astragaloside IV, acteosin glucoside The addition a...

Embodiment 2

[0036] Methods as below:

[0037] (1) Grinding: Dry fresh astragalus membranaceus for 4 hours at 70°C and put it into a clean high-speed grinder. After starting, take out 1kg after grinding for 20 seconds, add it to the infrared plasma surface modification device, and put it into the instrument Pure water 5Kg, add the nano-scale particle of astragaloside IV, acteocoside glucoside simultaneously, particle diameter is 20nm, the addition of the nano-scale particle of described astragaloside IV, acteocoside glucoside is 4ppm, temperature adopts normal temperature, vacuum degree 20mmHg, start activation, after 3.5 hours, filter with a filter to obtain the extract of Astragalus membranaceus, after testing, in the extract of Astragalus membranaceus, calculated as a dry product, there are astragaloside IV 0.0007kg and acteosin glucoside 0.00035 kg.

[0038] (2) Waste residue: After filtering in step (1), dry the waste residue at 70°C for 4 hours and take it out, which can be used as f...

Embodiment 3

[0041] Methods as below:

[0042] (1) Grinding: Dry the fresh astragalus membranaceus for 4 hours at 70°C and put it into a clean high-speed grinder (equipment manufacturer: Jiangsu Dongsheng Machinery Co., Ltd., type FS300). After starting, grind for 20 seconds and take it out Take out 1 kg, add it to the infrared plasma surface modification device, put 11Kg of pure water into the instrument, and add nanoscale particles of astragaloside IV and acteocoside at the same time, and the nanoscale particles of astragaloside IV and acteocoside The addition amount is 5ppm, the particle size is 50nm, the temperature adopts normal temperature, the vacuum degree is 20mmHg, and the activation is started. After 4 hours, filter with a filter to obtain the Astragalus extract. After testing, the Astragalus extract is calculated as a dry product. glycoside 0.0008 kg, calycosin glucoside 0.0004 kg.

[0043] (2) Waste residue: The waste residue obtained by filtering in step (1) is dried at 70°C...

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Abstract

The invention relates to a method for preparing the radix astragali extract at the room temperature. The method comprises the following steps: drying astragalus, pulverizing, and putting into an infrared plasma surface modification device; The device comprises: a sealed and vacuumizable shell, an ultrasonic tank body arranged in the shell, an infrared ray emitting device and a plasma generating device arranged on the ultrasonic tank body; Water is added into the ultrasonic tank, and nanometer-sized particles of astragaloside IV and calycosin are added at room temperature with vacuum degree of10-25mmHg, star an ultrasonic device, an infrared ray emitting device and a plasma generate device, extracting and filtering to obtain astragalus extract. The preparation method of the astragalus extract under normal temperature has the characteristics of low energy consumption, clean environment protection and high yield.

Description

technical field [0001] The invention belongs to the technical field of extracting effective components of traditional Chinese medicinal materials, and in particular relates to a preparation method of astragalus extract at normal temperature. Background technique [0002] Traditional Chinese medicine mainly originated in China, and is a drug used to prevent, diagnose, treat diseases or regulate human body functions under the guidance of TCM theory. Most of them are herbal medicines, but there are also animal medicines, mineral medicines and some chemical and biological products. Traditional Chinese medicine is divided into Chinese patent medicine and traditional Chinese medicinal materials according to the processing technology. For Chinese herbal medicines, how to efficiently extract their active ingredients is one of the current research hotspots. [0003] For a long time, clinical Chinese herbal medicines have been mainly decocted in water. The traditional decoction ext...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61L2/14A61L2/025A61L2/08
CPCA61K36/481A61K2236/10A61K2236/331A61L2/0011A61L2/0058A61L2202/21
Inventor 薛超薛纪良
Owner JIANGSU XINGYE POLYMERIZATION CO LTD
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