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Traditional Chinese medicine composition for treating blood stasis, swelling and pain after bone fracture and method for preparing traditional Chinese medicine composition

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, drug delivery, medical formula, etc., can solve the problems of not helping the absorption and diffusion of local hematoma, and can not fundamentally solve the inflammatory exudation reaction, so as to improve the bioavailability , reduce economic burden, and have significant and reliable curative effect

Inactive Publication Date: 2019-03-05
李卫国
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these treatment methods can achieve a certain curative effect, they cannot fundamentally solve the inflammatory exudation reaction, and do not help the absorption and diffusion of the local hematoma.

Method used

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  • Traditional Chinese medicine composition for treating blood stasis, swelling and pain after bone fracture and method for preparing traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating blood stasis, swelling and pain after bone fracture and method for preparing traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating blood stasis, swelling and pain after bone fracture and method for preparing traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0033] Embodiments 1-3 are respectively composed of the pharmaceutical compositions of the raw materials in proportions by weight shown in Table 1 below:

[0034] Table 1 implements the proportioning by weight of raw materials 1-3.

[0035]

Embodiment 1、2

[0036] The preparation method of embodiment 1,2:

[0037] According to the raw material ratio of above-mentioned embodiment 1,2, spray, liniment are made respectively by the method for following main steps.

[0038] Step 1: Make coarse powder of raw materials Duyiwei, safflower, wine rhubarb, vinegar corydalis, gardenia, and raw cattail, mix the raw materials with a little 75% ethanol, then evenly put them into the percolator, and then add 4 75% ethanol twice the weight of the drug, let it stand for 24 hours, so that the ethanol fully soaks the bulk drug and discharges the air to prepare for percolation. During the diafiltration, the dripping speed of the filtrate is controlled at a constant speed, and the diafiltration can be completed within 48 hours to obtain the leachate A1.

[0039] Step 2: Dissolve Glauber's salt, borneol, and menthol in leachate A1, stir and mix well, let stand for 24 hours, filter, control the ethanol concentration of the filtrate at 70% to 75%, fill ...

Embodiment 3

[0040] The preparation method of embodiment 3:

[0041] According to the raw material proportioning of above-mentioned embodiment 3, by the method for following main steps, make the ointment for external use.

[0042] Step 1: Add raw materials such as Duyiwei, safflower, wine rhubarb, vinegar corydalis, gardenia, and raw cattail into water 5 times the weight of the medicine, soak for 1.5 hours, boil with strong fire, then decoct with slow fire for 40 minutes, filter to obtain the filtrate B1.

[0043] Step 2: Second decoction: add water 3 times the weight of the medicine to the medicine dregs, boil with high fire, then decoct with slow fire for 40 minutes, filter to obtain filtrate B2.

[0044] Step 3: Combine the filtrates B1 and B2, settle for 12 hours, take the supernatant and heat and concentrate to thick paste to obtain thick paste B3.

[0045] Step 4: Grind Glauber's salt, borneol, and menthol finely for later use. Heat and melt beeswax, filter, heat and stir with filte...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating blood stasis, swelling and pain afterbone fracture and a method for preparing the traditional Chinese medicine composition. The traditional Chinese medicine composition and the method are characterized in that the traditional Chinese medicine composition comprises 18 parts of herba lamiophlomis, 12 parts of flos carthami, 12 parts of wine-processed radix et rhizoma rhei, 12 parts of vinegar-processed rhizoma corydalis, 12 parts of fructus gardeniae, 10 parts of pollen typhae, 10 parts of natrii sulfas, 6 parts of borneolum syntheticum and 6 parts of menthol; the method includes preparing coarse powder from crude medicines, uniformly mixing the crude medicines by little 75% ethyl alcohol, uniformly loading the crude medicines into percolators, adding 75% ethyl alcohol into the crude medicines, allowing the 75% ethyl alcohol and the crude medicines to stand still for 24 hours, sufficiently soaking the crude materials in the ethyl alcohol and exhausting air for percolation. The crude medicines include the herba lamiophlomis, the flos carthami, the wine-processed radix et rhizoma rhei, the vinegar-processed rhizoma corydalis, the fructus gardeniae and the pollen typhae. The 75% ethyl alcohol added into the percolators accounts for 4 times the weight of the medicines. The traditional Chinese medicine composition and the method have the advantages that the traditional Chinese medicine composition is obvious in effective rate when used for treating local swelling and pain at early fracture stages; fast curative effects can be realized by the traditional Chinese medicine composition, the traditional Chinese medicinecomposition is short in treatment time, and suffering can be relieved for patients to a great extent.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating blood stasis, swelling and pain after bone trauma and a preparation method thereof. Background technique [0002] It is well known that in the early stage of bone injury patients, local soft tissue and blood circulation are damaged, inflammatory exudation is obvious, and severe pain occurs. Local hemorrhage, blocked venous return, and obvious local swelling of the limbs affect the blood supply of the distal limbs. In severe cases, compartment syndrome may form, resulting in adverse consequences such as nerve entrapment and degeneration of the distal limbs or limb necrosis. If the inflammation is not early suppressed or the blood stasis cannot be fully absorbed and diffused, the prognosis will often be due to the accumulation of blood stasis in the soft tissue, local soft tissue adhesion dege...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61K9/12A61K9/06A61P29/00A61K33/04A61K31/045
CPCA61K36/88A61K9/0014A61K9/06A61K9/12A61K31/045A61K33/04A61K36/286A61K36/53A61K36/66A61K36/708A61K36/744A61K47/44A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 李卫国王敦庆王彦哲
Owner 李卫国
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