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Nasal nursing spray

A spray and nasal technology, applied in the field of cleaning agents, can solve the problems of inability to achieve symptom relief, limited performance of dissolving nasal mucus, etc., and achieve the effects of good bactericidal and bacteriostatic properties, good continuous dissolution ability, and function recovery.

Active Publication Date: 2019-03-19
广州蓓思语生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the inventor found during the experiment that the surfactant selected by CN200880110989 has limited performance in dissolving nasal mucus, and after dissolving, it can only be maintained for a short time, and cannot achieve long-term symptom relief.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A nasal care spray comprises the following components according to weight percentage: 0.22% sodium pyruvate, 0.05% pyruvic acid, 0.05% polyhexamethylene biguanide, 0.1% Gemini surfactant, and the balance is physiological sea water.

[0021] Above-mentioned Gemini surfactant is quaternary ammonium salt cationic surfactant, and structural formula is as follows:

[0022]

[0023] The appearance of this product is transparent liquid, no cytotoxicity in vitro, no intradermal irritation, no delayed hypersensitivity reaction; physical and chemical indicators: pH: 6.0-8.0, heavy metals (calculated as Pb) should be ≤ 20mg / ml; hygienic indicators : The total number of bacterial colonies should be ≤100cfu / ml, the total number of fungal colonies should be ≤10cfu / ml, no coliforms, Pseudomonas aeruginosa and Staphylococcus aureus were detected.

Embodiment 2

[0025] A nasal cavity care spray comprises the following components according to weight percentage: 0.22% sodium pyruvate, 0.05% pyruvic acid, 0.05% polyhexamethylene biguanide, and the balance is physiological sea water.

Embodiment 3

[0027] A nasal care spray comprises the following components according to weight percentage: 0.22% sodium pyruvate, 0.05% pyruvate, 0.05% polyhexamethylene biguanide, 0.1% Tween 80, and the balance is physiological sea water.

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Abstract

The invention provides a nasal nursing spray, and also provides a use method of the spray. The spray contains the following components by weight percentage: 0.22% of sodium pyruvate, 0.05% of pyruvicacid, 0.05% of preservative, 0.1% of Gemini surfactant, and the balance of physiologic seawater. The nasal nursing spray provided by the invention can effectively dissolve nasal mucus and relieve thesymptoms of snot and nasal congestion, has a relatively strong antibacterial ability, can be used for the nasal rinsing of patients of nasal diseases such as acute and chronic rhinitis, allergic rhinitis, nasal polyp and nasosinusitis, and also can be used for the daily nursing of the nasal cavity, and nasal rinsing after rhinitis operation and chemotherapy.

Description

technical field [0001] The invention belongs to the field of cleaning agents, in particular to a nursing spray for cleaning nasal cavity. Background technique [0002] Rhinitis is an inflammatory disease of the nasal cavity, which is the inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of nasal mucosa. Clinical symptoms include nasal congestion, nasal discharge, decreased sense of smell, headache, dizziness, etc. People can use oral medicine or drug spray to treat rhinitis, and at the same time, nasal spray can also be used to clean the nasal cavity to relieve some symptoms. [0003] CN2012100521550 discloses a sodium pyruvate nasal spray, its components include sodium pyruvate, pyruvic acid, isotonic regulator, preservative and water, for cleaning and removing harmful po...

Claims

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Application Information

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IPC IPC(8): A61K31/19A61K9/12A61K47/18A61H35/04A61P11/02
CPCA61H35/04A61K9/0043A61K9/12A61K31/19A61K47/186A61P11/02A61K2300/00
Inventor 黄敏郭俊喜
Owner 广州蓓思语生物科技有限公司
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