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Lactic acid hemodialysis concentration liquid and preparation method thereof

A technology of hemodialysis and concentrated solution, which is applied in the direction of blood diseases, medical formulas, extracellular fluid diseases, etc., can solve the problems of eye and nose irritation, no benefit to the human body, strong corrosion, etc., to achieve enhanced peristalsis and secretion, Improve biological activity and promote growth

Inactive Publication Date: 2019-03-26
武汉柯瑞迪医疗用品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The formula of the existing hemodialysis concentrate is to use glacial acetic acid as a Ph regulator. Glacial acetic acid itself is not beneficial to the human body. It is weakly acidic and highly corrosive in aqueous solution, and has an irritating effect on eyes and nose. The production process of glacial acetic acid is strong The pungent smell can make people extremely uncomfortable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A kind of lactic acid hemodialysis concentrated solution, comprises hemodialysis concentrated A liquid and hemodialysis concentrated B liquid:

[0021] The hemodialysis concentrated liquid A includes the following components in mass concentration: sodium chloride 200g / L, potassium chloride 4g / L, calcium chloride 6g / L, magnesium chloride 2g / L and lactic acid 8g / L, the blood The mass concentration of sodium bicarbonate in the dialysis concentration B liquid is 80g / L.

[0022] A preparation method of the above-mentioned lactic acid hemodialysis concentrate, comprising the following steps:

[0023] S1. Prepare hemodialysis concentrated solution A with a sodium chloride concentration of 200g / L, a potassium chloride concentration of 4g / L, a calcium chloride concentration of 6g / L, a magnesium chloride concentration of 2g / L and a lactic acid concentration of 8g / L. spare;

[0024] S2, configure hemodialysis concentrated B solution with a sodium bicarbonate concentration of 80g...

Embodiment 2

[0027] A kind of lactic acid hemodialysis concentrated solution, comprises hemodialysis concentrated A liquid and hemodialysis concentrated B liquid:

[0028] The hemodialysis concentrated liquid A includes the following components in mass concentration: sodium chloride 210.7g / L, potassium chloride 5.21g / L, calcium chloride 7.718g / L, magnesium chloride 3.558g / L and lactic acid 9.46g / L L, the mass concentration of sodium bicarbonate in the hemodialysis concentrated liquid B is 84.01g / L.

[0029] A preparation method of the above-mentioned lactic acid hemodialysis concentrate, comprising the following steps:

[0030] S1. Prepare blood with a sodium chloride concentration of 210.7g / L, a potassium chloride concentration of 5.21g / L, a calcium chloride concentration of 7.718g / L, a magnesium chloride concentration of 3.558g / L and a lactic acid concentration of 9.46g / L Dialyze the concentrated solution A, set aside;

[0031] S2. Configure hemodialysis concentrated B solution with a ...

Embodiment 3

[0034] A kind of lactic acid hemodialysis concentrated solution, comprises hemodialysis concentrated A liquid and hemodialysis concentrated B liquid:

[0035] The hemodialysis concentrated liquid A includes the following components in mass concentration: sodium chloride 220g / L, potassium chloride 6g / L, calcium chloride 8g / L, magnesium chloride 4g / L and lactic acid 12g / L, the blood The mass concentration of sodium bicarbonate in the dialysis concentration B liquid is 90g / L.

[0036] A preparation method of the above-mentioned lactic acid hemodialysis concentrate, comprising the following steps:

[0037] S1. Prepare hemodialysis concentrated liquid A with a sodium chloride concentration of 220g / L, a potassium chloride concentration of 6g / L, a calcium chloride concentration of 8g / L, a magnesium chloride concentration of 4g / L and a lactic acid concentration of 12g / L. spare;

[0038] S2, configure hemodialysis concentrated B solution with a sodium bicarbonate concentration of 90g...

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Abstract

The invention discloses lactic acid hemodialysis concentration liquid and a preparation method thereof. The lactic acid hemodialysis concentration liquid comprises hemodialysis concentration liquid Aand hemodialysis concentration liquid B, wherein the hemodialysis concentration liquid A is prepared from the following substances of sodium chloride, potassium chloride, calcium chloride, magnesium chloride, lactic acid and water; the hemodialysis concentration liquid B is prepared from the following substances of sodium bicarbonate and water. The lactic acid hemodialysis concentration liquid andthe preparation method provided by the invention have the advantages that the production process of the lactic acid hemodialysis concentration liquid is friendly to people; no irritation is caused onthe eyes and noses.

Description

technical field [0001] The invention relates to the field of hemodialysis concentrate. More specifically, the present invention relates to a lactic acid hemodialysis concentrate and a preparation method thereof. Background technique [0002] Hemodialysis (HD) is one of the renal replacement therapies for patients with acute and chronic renal failure. It drains the blood from the body to the outside of the body through a dialyzer composed of countless hollow fibers. The blood and the electrolyte solution (dialysate) with similar concentration to the body are inside and outside the hollow fibers through diffusion, concentration gradient and convection. The principle is to carry out electrolyte balance, take away metabolic waste in the body, maintain electrolyte and acid-base balance; at the same time remove excess water in the body, the whole process is called hemodialysis. The formula of the existing hemodialysis concentrate is to use glacial acetic acid as a Ph regulator. ...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K9/08A61P7/08A61K33/06A61K31/19A61K33/00
CPCA61K9/08A61K31/19A61K33/00A61K33/06A61K33/14A61P7/08A61K2300/00
Inventor 余磊
Owner 武汉柯瑞迪医疗用品有限公司
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