An electrochemical sensor for detecting tyramide molecules, its preparation method and application

Abstract

An electrochemical sensor for detecting tyramide molecules and its preparation method and application. The sensor is a cyclodextrin-reduced graphene oxide conjugate modified glassy carbon electrode electrochemical sensor, wherein the cyclodextrin-reduced graphene oxide conjugate is composed of ethylenediamine cyclodextrin and graphene oxide through a covalent bond connected and further reduced by ascorbic acid; the modified electrode is prepared by drop-coating the cyclodextrin-reduced graphene oxide conjugate dispersion on the glassy carbon electrode and then drying it. The electrochemical sensor provided by the present invention makes full use of the super-strong electron conductivity of graphene and the supramolecular recognition characteristics of cyclodextrin to generate sensitive electrochemical response signals to tyramide molecules, thereby realizing the electrochemical detection of tyramide molecules. The detection results are convenient, fast, sensitive and accurate; the preparation process of the electrochemical sensor is simple, easy to implement and low in material cost, and has great application prospects in the field of sensitive detection of tyramide molecules.

Description

【Technical field】 [0001] The invention relates to the technical field of supramolecular functional materials and electrochemical sensing, in particular to a method for preparing a cyclodextrin / graphene conjugate electrochemical sensor for tyramide molecular detection. 【Background technique】 [0002] Tyramine, namely 4-hydroxyphenylethylamine, is mostly used in food additives and organic synthesis. Thus, tyramine as a parent structure widely exists in alkaloids, amino acids, peptides and synthetic drug molecules. Therefore, it is of vital significance to establish a convenient, rapid, sensitive and accurate detection method for tyramide molecules. Electrochemical sensing analysis method has attracted more and more attention due to its advantages of fast, efficient, accurate and sensitive, simple equipment, and low price. In particular, the application of new functional materials with excellent physical and chemical properties to the construction of electrochemical sensors t...

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Problems solved by technology

However, graphene is easy to aggregate and accumulate, and graphene-based electrochemical sensors have poor selectivity for substrate detection, which limits its application.

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