Absorbable bone wax with hemostasis function, and preparation method thereof

Abstract

The invention discloses absorbable bone wax with a hemostasis function. The absorbable bone wax is prepared from the following raw materials: solid and water, wherein the solid is prepared from crosslinking hyaluronic acid, calcium phosphate and soluble starch; the weight of water is 20-100% of the weight of the solid; the weight ratio of the solid is that the ratio of the crosslinking hyaluronicacid, the calcium phosphate and the soluble starch is (20-70):(20-50):(0-10). According to the bone wax disclosed by the invention, the defects that traditional bone wax has poor biocompatibility, isnondegradable and affects bone healing can be eliminated. While a good hemostasis effect of the traditional bone wax is kept, the bone wax disclosed by the invention can be naturally degraded in the body without causing late period relevant complications due to residues.

Description

technical field

[0001] The invention relates to the technical field of biomedical materials, in particular to an absorbable bone wax with a hemostatic function and a preparation method thereof. Background technique

[0002] During orthopedic, thoracic, and neurosurgery operations, bone destruction is often involved, resulting in bleeding from the bone surface. Due to the rich blood supply, it is difficult to stop this bleeding by conventional methods such as electrocoagulation, forceps, hemostatic gauze, and gelatin sponge packing. Therefore, bone wax is often used clinically to stop bleeding on cancellous bone wounds. The main components of traditional bone wax are beeswax, vaseline, etc. Its hemostatic mechanism is to fill and seal the bleeding bone surface through the mechanical physical barrier, and it can stop bleeding quickly and is widely used in clinical practice. However, the traditional bone wax has poor biocompatibility and is difficult to be degraded and absorbe...

Images