Framework molecules based on folding and assembling of cyclic polymers and preparation method thereof

Abstract

The invention discloses framework molecules based on folding and assembling of cyclic polymers and a preparation method thereof. The framework molecules have a chemical name of cyclic polyesters whichcomprise cyclic di-polyester namely 1-Ar, cyclic tri-polyester namely 2-Ar, cyclic tetra-polyester namely 3-Ar, cyclic penta-polyester namely 4-Ar and cyclic hexa-polyester namely 5-Ar, wherein Ar represents one selected from the group consisting of phenyl-1,4-diyl namely Ph, biphenyl-4,4'-diyl namely BP, 2,2-bipyridine-5,5'-diyl namely BPy and pyrene-2,7-diyl namely Pr, which have structural formulas as described in the specification. The preparation method for the framework molecules comprises the steps of carboxyl acylating chlorination with a thionyl chloride reflux method, ester exocondensation with a solvent-free method, and cyclic polyester separation with a gradient elution method. According to the invention, by utilization of the characteristic of formation of a nanometer cavitywith a larger size through intermolecular assembling, four series of cyclic polyester supramolecular host compounds are developed. The cyclic polyesters provided by the invention have the advantages of fewer synthetic steps, mild reaction conditions and low separation and purification cost.

Description

technical field [0001] The invention relates to supramolecular chemistry, in particular to a class of framework molecules based on ring polymer folding and assembly and a preparation method thereof. Background technique [0002] Supramolecular chemistry is an important branch of chemistry, which mainly realizes the assembly, recognition and reaction of molecules by means of non-covalent interactions between molecules. Compared with the strong interaction of covalent bonds in traditional chemistry, the research objects of supramolecular chemistry are weaker and recoverable intermolecular interactions, such as hydrogen bonds, metal coordination, π-π stacking, hydrophobic / philic Water effects, van der Waals forces, superposition, etc. In order to make full use of molecular self-assembly, folding, recognition, host-guest inclusion and other functions, and make these weak interactions exert unexpected effects, the host molecules participating in supramolecular interactions are r...

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Problems solved by technology

[0003] Nevertheless, the disadvantages of the above supramolecular systems are also obvious

From a structural point of view, in addition to natural enzymes, the above-mentioned host molecules, especially the synthetic host molecules, have high molecular rigidity and small cavity size, which greatly restricts the diversity of molecular assembly and recognition. ; while metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) are two types of materials, the molecular cavity is too deep, the molecular geometry is single, the recognition ability of the guest molecule is poor, and the exchange of molecules inside and outside the pores is difficult.

From the perspective of synthesis, although cyclodextrin has a wide range of sources, the chemical modification is very complicated; the synthesis of main molecules such as calixarene and MOFs and COFs is also difficult, such as many synthesis steps, high reaction temperature, high cost of separation and purification, etc.

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