A kind of amphiphilic hybrid arm graft polymer and its preparation method and application based on one-pot method
A graft polymer and amphiphilic technology, which is applied in the field of amphiphilic hybrid arm graft polymer and its preparation based on a one-pot method, can solve the problems of troublesome operation and many reaction steps, and the method is simple and easy to operate , mild reaction conditions, good reproducibility
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Embodiment 1
[0026] (1) Synthesis of P(MMA 40 -co-HEMA 60 ) random copolymer:
[0027] Add MMA (0.40g, 4.0mmol), HEMA (0.78g, 6.0mmol), EBiB (19.50mg, 0.1mmol), PMDETA (20.60mg) and 3mL to a 50mL Schlenk bottle equipped with magnets isopropanol, then "freeze and vacuum-thaw" twice, then add CuBr (14.40mg, 0.1mmol) under the condition of nitrogen, and then freeze and pump for 2 minutes, thaw, put the Schlenk bottle into the set Temperature of the oil bath, the reaction 12h. After the reaction was completed, the Schlenk bottle was placed in the lower layer of the refrigerator for 5 minutes, and then the reaction mixture was diluted with 20 mL of tetrahydrofuran. Immediately afterwards, the diluted reaction mixture was passed through a column filled with neutral alumina, and the liquid was collected; then most of the solvent was removed with a rotary evaporator, and the remaining solvent was added to petroleum ether to obtain a white precipitate, which was vacuum-dried. get P(MMA 40 -co-...
Embodiment 2
[0039] Synthesize P(MMA in step (1) 40 -co-HEMA 60 ) in the process of random copolymer change reaction solvent isopropanol into tetrahydrofuran (THF), other implementation conditions and embodiment 1 synthetic P (MMA 40 -co-HEMA 60 ), we characterized the resulting polymer P(MMA 40 -co-HEMA 60 ) random copolymer, the number-average molecular weight of the polymer is the same as the design value, but the molecular weight distribution rises more, which is 1.26, and the synthetic graft polymer needs the matrix polymer to have a molecular weight distribution as narrow as possible, so tetrahydrofuran is the reaction solvent Not suitable.
Embodiment 3
[0041] Synthesize P(MMA in step (1) 40 -co-HEMA 60 ) in the process of random copolymer change reaction solvent Virahol into acetonitrile, other implementation conditions and embodiment 1 synthetic P (MMA 40 -co-HEMA 60 ), we characterized the resulting polymer P(MMA 40 -co-HEMA 60 ) random copolymer, the number-average molecular weight of the polymer is the same as the design value, but the molecular weight distribution rises more, which is 1.28. Synthetic graft polymer requires the matrix polymer to have as narrow a molecular weight distribution as possible, so acetonitrile is the reaction solvent Not suitable.
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