Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Angelica sinensis effective component extracting method and extracts of angelica sinensis

An extraction method and technology for active ingredients, which are applied in the field of extraction of active ingredients of Angelica sinensis, can solve the problems of solvent residue, difficult to handle, energy waste, easy decomposition, etc., and achieve the effects of improving the utilization rate of raw materials, reducing the amount of solvent, and improving the extraction efficiency.

Inactive Publication Date: 2019-06-11
北京国康本草物种生物科学技术研究院有限公司
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The problem in the prior art that the present invention solves is: the existing method for extracting the active ingredients of Angelica sinensis mostly takes a single target product as the extraction target, and the waste of energy is serious. Unstable under the environment, easy to decompose or be oxidized, resulting in low yield of traditional steam distillation, and solvent extraction, such as using petroleum ether as the extraction solvent, the problem of solvent residue in the obtained product is difficult to deal with, which brings safety to subsequent use Hidden danger

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment one provides a kind of extracting method of active ingredient of Angelica sinensis, comprises the steps:

[0048] (1) Take the dried root of Angelica sinensis, powder it through a No. 3 sieve, take 10g of Angelica sinensis powder, add 100mL of water, add 0.01g of hemicellulase and 0.01g of cellulase, stir well, keep warm at 40°C for 5 hours, and filter to obtain cake 1 and extract 1;

[0049] (2) Heat and concentrate the extract 1 to 10% of the original volume, add 50 ml of absolute ethanol, stir for 30 minutes, cool, filter, and dry to obtain 3.5 g of Angelica polysaccharide and extract 2;

[0050] (3) adding volume fraction in filter cake 1 is the ethanol 50g of 40% concentration, extracts 1h at 60 ℃ then, filters to obtain filtrate 3 and filter cake 3; Continue to add volume fraction in filter cake and be the ethanol 50g of 40% concentration , and then extracted at 60°C for 1 h, and repeated the extraction 3 times accordingly; the combined filtrates were ...

Embodiment 2

[0061] Embodiment two provides a kind of extracting method of active ingredient of Angelica sinensis, comprises the steps:

[0062] (1) Take the dried root of Angelica sinensis, powder it through a No. 3 sieve, take 10g of Angelica sinensis powder, add 50mL of water, add 0.01g of pectinase, 0.01g of hemicellulase and 0.01g of cellulase, stir well and keep warm at 35°C 4 hours, filtered to obtain filter cake 1 and extract 1;

[0063] (2) Heat and concentrate the extract 1 to 15% of the original volume, add 80 ml of absolute ethanol, stir for 30 minutes, cool, filter, and dry to obtain 3.2 g of Angelica polysaccharide and extract 2;

[0064] (3) Adding volume fraction in filter cake 1 is the ethanol 80g of 60% concentration, extracts 30min at 80 ℃ then, filters to obtain filtrate 3 and filter cake 3; Continue to add volume fraction in filter cake and be the ethanol 80g of 60% concentration , and then extracted at 80°C for 30 minutes, and repeated the extraction 4 times accordin...

Embodiment 3

[0068] Embodiment three provides a kind of extracting method of active ingredient of Angelica sinensis, comprises the steps:

[0069] (1) Take the dried root of Angelica sinensis, powder it through a No. 3 sieve, take 10g of Angelica sinensis powder, add 70mL of water, add 0.01g of pectinase, 0.02g of cellulase, 0.01g of hemicellulase and 0.01g of protease, and stir well Insulated at 20°C for 5 hours, filtered to obtain filter cake 1 and extract 1;

[0070] (2) Heat and concentrate the extract 1 to 8% of the original volume, add 100 ml of absolute ethanol, stir for 30 minutes, cool, filter, and dry to obtain 3 g of Angelica polysaccharide and extract 2;

[0071] (3) Adding volume fraction in filter cake 1 is the ethanol 70g of 50% concentration, then extracts 1h at 80 ℃, filters to obtain filtrate 3 and filter cake 3; Continue to add volume fraction in filter cake and be the ethanol 70g of 50% concentration , and then extract at 80°C for 2 hours, and repeat the extraction twi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of processing of natural products, in particular to an angelica sinensis effective component extracting method and extracts of angelica sinensis. According to the angelica sinensis effective component extracting method, in the same production technology, multiple kinds of effective components in the angelica sinensis are extracted separately, the limitation of single target product extraction and separation is gotten rid of, the utilization rate of an angelica sinensis raw material is greatly improved, the extraction cost is reduced, moreover, the technologyis simple, operation is simple and convenient, and the equipment requirements are low. Enzymolysis is used for assisting in extraction, the ferulic acid extraction efficiency nearly doubles, moreover,on the premise of controlling parameters of aqueous extraction and alcohol extraction, for extraction of flavone and ligustilide, the solvent dosage is reduced, good yields are obtained, and the angelica sinensis effective component extracting method has significant economic values.

Description

technical field [0001] The invention relates to the field of natural product or raw material processing, in particular to a method for extracting active ingredients of angelica sinensis. Background technique [0002] Angelica, (scientific name: Angelica sinensis,) alias dry return, perennial herb. China introduced Angelica sinensis from Europe in 1957. It is mainly produced in the southeast of Gansu, and its root can be used as medicine, which is one of the most commonly used traditional Chinese medicines. It has the effects of nourishing blood and blood, regulating menstruation and relieving pain, moistening dryness and smoothing intestines, anti-cancer, anti-aging and improving immunity. [0003] Ferulic acid, volatile oil of Angelica sinensis, flavonoids and Angelica polysaccharides are the main active ingredients in Angelica sinensis. Ferulic acid (sodium ferulate) has anti-platelet aggregation, inhibits the release of platelet 5-hydroxytryptamine, inhibits the genera...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07C51/42C07C59/64C07D307/88A61K36/232
Inventor 王代军陈松
Owner 北京国康本草物种生物科学技术研究院有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com