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Method for preparing wound hemostatic bag and porous hemostatic agent particles

A hemostatic agent and wound technology, applied in the field of medical supplies, can solve the problems of limited contact area between blood and hemostatic agent, poor blood permeability, inconvenient debridement, etc., achieve excellent water absorption and permeability, promote thrombosis, prevent recurrence bleeding effect

Inactive Publication Date: 2019-07-05
瞿应良
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the hemostatic powder is directly contained in a hydrophilic bag, the hemostatic powder is a fine powder, which is easy to leak out and remain on the wound, and it is inconvenient to debride the wound after hemostasis. After the blood passes through the hydrophilic bag, due to the small gap between the hemostatic powder and poor permeability, the blood can only contact the hemostatic powder at the bottom of the hydrophilic bag. The permeability of blood in the hemostatic powder is poor, and the blood is in contact with hemostatic agent The area is limited, and the use is still limited

Method used

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  • Method for preparing wound hemostatic bag and porous hemostatic agent particles

Examples

Experimental program
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Effect test

specific Embodiment 1

[0026] A wound hemostatic bag, the hydrophilic gauze bag is filled with porous hemostatic agent particles to make the wound hemostatic bag, the outside of the wound hemostatic bag is provided with a moisture-proof aluminum foil bag, and the side of the moisture-proof aluminum foil bag is provided with sawtooth, the sawtooth is used as a tear hole, porous The active ingredients of hemostatic agent granules include zeolite powder, kaolin clay powder, and bentonite powder. %, bentonite powder 10%, water-soluble binder 5%, calcium bicarbonate 5%, granulation, 90 ℃ drying, the polyvinylpyrrolidone that the water-soluble binder of this embodiment adopts, the active ingredient of hemostatic agent The powder passes through an 80-mesh sieve, and the particle diameter of the porous hemostatic agent is 4-5mm.

specific Embodiment 2

[0028]A wound hemostatic bag, the hydrophilic cotton bag is filled with porous hemostatic agent particles to make the wound hemostatic bag, the outside of the wound hemostatic bag is provided with a moisture-proof aluminum foil bag, the side of the moisture-proof aluminum foil bag is provided with sawtooth, the sawtooth is used as a tear hole, and is porous The active ingredient of the hemostatic agent granule is zeolite powder, and the active ingredient of the hemostatic agent is bonded into granules by a water-soluble adhesive, and the mass percentage is 90% of kaolin powder, 8% of calcium bicarbonate, and 2% of water-soluble adhesive %, granulated, dried at 120°C, the polyvinylpyrrolidone and hypromellose mixture used in the water-soluble adhesive in this specific example, the mass ratio of polyvinylpyrrolidone and hypromellose mixture is 1:1, and the hemostasis The active ingredient powder of the agent passes through a 90-mesh sieve, and the particle diameter of the porous ...

specific Embodiment 3

[0030] A wound hemostatic bag, the hydrophilic non-woven bag is filled with porous hemostatic agent particles to make the wound hemostatic bag, the outside of the wound hemostatic bag is provided with a moisture-proof plastic bag, and the side of the moisture-proof plastic bag is provided with sawtooth, the sawtooth is used as a tear opening, and the hole is porous The active ingredient of the hemostatic agent granule is bentonite powder, and the active ingredient of the hemostatic agent is bonded into granules by a water-soluble adhesive, and the mass percentage is 80% of bentonite powder, 10% of water-soluble adhesive, and 10% of calcium bicarbonate. %, granulation, and drying at 150°C. In this specific example, polyvinylpyrrolidone is used as the water-soluble binder. The active ingredient powder of the hemostatic agent passes through a 90-mesh sieve, and the particle diameter of the porous hemostatic agent is 0.6-1 mm.

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Abstract

The invention relates to a method for preparing a wound hemostatic bag and porous hemostatic agent particles. Effective components of a hemostatic agent comprise one or more of zeolite powder, kaolinpowder and bentonite powder, the effective components of the hemostatic agent and a water-soluble adhesive are added with calcium bicarbonate, and are granulated, particles are dried at the temperature of 90-150 DEG C, thus, the porous hemostatic agent particles are prepared, and the porous hemostatic agent particles are packaged in a hydrophilic bag to prepare the wound hemostatic bag. The poroushemostatic agent particles have compact pore channels, and are good in water absorption and permeability, a water-soluble adhesive dissolves when meeting water in blood, the effective contact area between the hemostatic agent as well as calcium carbonate and blood is increased, coagulation reaction is accelerated, and thrombosis is promoted. The wound hemostatic bag is good in hemostatic effect,the hemostatic bag can be removed after hemostasis, and then hemostatic bag can be carried out.

Description

technical field [0001] The invention belongs to the technical field of medical supplies, and in particular relates to a preparation method of a wound hemostatic pack and porous hemostatic agent particles. Background technique [0002] At present, the traditional pre-hospital trauma hemostatic products include medical gauze, tourniquet, wound paste, hemostatic powder, etc., which are widely used in the military, firefighting, emergency centers, public security, frontier defense, field exploration, household emergency first aid and other fields. , Coal mines, public transportation, and public places where people gather to deal with trauma and bleeding in unexpected situations are necessary hemostatic products, and they can play an important role in disaster rescue (such as earthquakes, explosions) and emergency bleeding in sudden traffic accidents. However, there are certain deficiencies in the use of the above-mentioned products. When using medical gauze, it is necessary to e...

Claims

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Application Information

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IPC IPC(8): A61L24/00A61L24/02A61L24/08A61L24/06
CPCA61L24/001A61L24/0015A61L24/0036A61L24/02A61L24/06A61L24/08A61L2300/102A61L2300/418A61L2400/04C08L1/284C08L39/06
Inventor 瞿应良
Owner 瞿应良
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