Multifunctional fluorescent probe having ESIPT and AIE properties and preparation method and application thereof

Abstract

The invention relates to a multifunctional fluorescent probe having ESIPT and AIE properties and a preparation method and application thereof. The preparation method of the fluorescent probe includesthe steps that 2-picolinic acid is dissolved in dried dichloromethane, benzotriazole-N,N,N',N'-tetramethylurea hexafluorophosphate is added for stirring for 30 minutes, then 2-(2'-aminophenyl)benzothiazole and triethylamine are added, and the whole mixture is stirred at the room temperature and placed overnight; after a reaction is completed, a solvent is evaporated and removed under reduced pressure, residues are subjected to column chromatography isolation, and the fluorescent probe N-(2-(2'-benzothiazolyl)phenyl)picolinamide is obtained. A synthesis method of the fluorescent probe is simple, a product separation and purification process is simple, and the fluorescent probe has the ESIPT and AIE properties, can be used for monitoring analysis and tracing of copper ions and pyrophosphatein a water environment system, and has high sensitivity in determination of target ions.

Description

technical field [0001] The invention relates to the field of functional materials, in particular to a multifunctional fluorescent probe with ESIPT and AIE properties and its preparation method and application. Background technique [0002] Fluorescent recognition of copper ions and pyrophosphate (PPi) is of great significance in life sciences and environmental monitoring, and has attracted much attention in recent years. Relay identification enables the identification of two ions to be performed continuously under the same test conditions, which has the obvious advantage of simple operation. Many of the currently reported fluorescent probes that can be used for relay recognition of copper ions and pyrophosphate need to be used in mixed solvents containing more organic solvents, which is not conducive to environmental protection. Few fluorescent probes that can recognize copper ions and pyrophosphate in aqueous solution have the disadvantage of complicated synthesis process....

AI Technical Summary

Problems solved by technology

Many of the currently reported fluorescent probes that can be used for relay recognition of copper ions and pyrophosphate need to be used in mixed solvents containing more organic solvents, which is not conducive to environmental protection.

Few fluorescent probes that can relay copper ions and pyrophosphate in aqueous solution have the disadvantage of complex synthesis process

[0003] Using the excited-state intramolecular proton transfer (ESIPT) property, it is possible to obtain longer fluorescence emission from small molecule fluorophores, but when this type of probe is used in a mixed solvent with high water content, it is often due to poor solubility. However, it is constrained by the aggregation-induced quenching (ACQ) effect

[0004] At present, it has ESIPT and AIE properties, and can relay recognition of copper ions and pyrophosphate fluorescent probes in solvents with high water content, which has not been reported in the literature.

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