Fluorescent indicator combination, fluorescence array sensor, preparation methods of fluorescent indicator combination and fluorescence array sensor and application

A fluorescent indicator and fluorescence technology, which is applied in the direction of fluorescence/phosphorescence, instruments, scientific instruments, etc., can solve the problems of complex processing process, insufficient sensitivity, complex processing, etc., and achieve simple detection process, strong anti-interference ability, and simple production process Effect
CN109975253AActive Publication Date: 2019-07-05NINGBO INST OF MATERIALS TECH & ENG CHINESE ACADEMY OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
NINGBO INST OF MATERIALS TECH & ENG CHINESE ACADEMY OF SCI
Publication Date
2019-07-05

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Abstract

The invention discloses a fluorescent indicator combination, a fluorescence array sensor, preparation methods of the fluorescent indicator combination and the fluorescence array sensor and application. The fluorescent indicator combination comprises a plurality of carbon quantum dot-metal ion complexes formed by full-color fluorescent carbon quantum dots and various metal ions under conditions ofdifferent pH values. The fluorescent array sensor contains a fluorescent indicator; the sensor comprises a plurality of groups of response points; each group of response points comprise three or moreindependent response points respectively corresponding to excitation wavelengths of 360 nm, 450 nm, and 540 nm; and each of the response points comprises at least one carbon quantum dot-metal ion complex. The fluorescent array sensor of the invention can realize qualitative and semi-quantitative detection of four kinds of antibiotics such as tetracyclines, quinolones, beta-lactams and aminoglycosides; and the preparation process of the sensor is simple; the storage time of the sensor is long; the detection sensitivity of the sensor is high; and the sensor can realize simultaneous differentiation and detection of a plurality of antibiotics.
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Description

technical field

[0001] The present invention relates to an array sensor used for the detection and differentiation of antibiotics, in particular to a fluorescent indicator combination for detecting and distinguishing multiple types of antibiotics, a multi-channel fluorescent array sensor and a preparation method thereof, as well as its ability to realize multiple types of antibiotics at the same time The application in detection belongs to the technical field of food safety detection. Background technique

[0002] Antibiotics, which kill or inhibit the growth of bacteria, have been produced in large quantities around the world over the past few decades and are used to treat various human and veterinary diseases. At present, excessive antibiotics are mostly found in milk, vegetables, grains, surface water and wastewater. Among them, the three classes of antibiotics with high detection frequency were quinolones, tetracyclines and sulfonamides. In order to ensure the qualit...

Claims

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