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Pharmaceutical composition for sun protection and repairing

A composition and drug technology, applied in the directions of pharmaceutical formulations, preparations for skin care, medical preparations containing active ingredients, etc., can solve problems such as affecting the secretion of sebaceous glands and sweat glands, skin allergies, etc., and achieve a good sunscreen repair effect and mild performance. , the effect of good application prospects and market prospects

Inactive Publication Date: 2019-07-26
GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] To sum up, most of the sunscreen products currently on the market are physical sunscreens and chemical sunscreens. Physical sunscreens will deposit a white layer on the skin surface, affecting the secretion of sebaceous glands and sweat glands. Chemical sunscreens need to be combined with cells before they can be absorbed Harmful part of ultraviolet rays, so it is easy to cause skin allergies

Method used

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  • Pharmaceutical composition for sun protection and repairing
  • Pharmaceutical composition for sun protection and repairing
  • Pharmaceutical composition for sun protection and repairing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] At room temperature, take 3.0 kg of Sanchaku, 2.5 kg of Zibeijinpan, 1.5 kg of wild sage, 1.5 kg of Artemisia fragrans, 1.5 kg of Camellia japonica, 1.5 kg of half-side flags, 1.5 kg of japonica japonica, and 1.5 kg of spider incense , mix the above drugs evenly. Add water and decoct 3 times, the amount of water added for the first time is 8 times the weight of the drug, the extraction time is 3 hours, the amount of water added for the second and third times is 6 times the weight of the drug, and the extraction time is 2 hours, the drug is obtained Composition extract; the drug extract is concentrated under reduced pressure to a relative density of 1.10-1.20 (50°C), cooled to room temperature to obtain a pharmaceutical composition concentrate; the pharmaceutical composition concentrate is filtered, and the filtrate is equipped with polystyrene-di Chromatography of vinylbenzene macroporous resin, so that the effective components in the concentrated solution of the pharma...

Embodiment 2

[0039] The pharmaceutical composition extract obtained in Example 1 is used to prepare the emulsion for sunscreen repair, and the weight percentage of the components is as follows:

[0040]

[0041]

[0042] Production process: Stir the water phase and oil phase separately at 85°C, fully dissolve the raw materials, then slowly add the oil phase to the water phase, homogenize at 3500r / min for 5 minutes, stir at 800r / min, and keep warm for 40min , then lower the temperature to 40°C, add preservative, homogenize at 3500r / min for 2 minutes, and stir at 800r / min for 30min.

[0043] The matrix components used in the preferred embodiment of the present invention are as described above, the matrix components used in this embodiment can maximize the efficacy of the pharmaceutical composition of the present invention. But the commonly used substrates that can be applied to cosmetics produced by other manufacturers can also be used in the present invention, as long as the dosage me...

Embodiment 3

[0046] This study evaluates its sunscreen effect by measuring the SPF value of the emulsion containing 1% pharmaceutical composition extract of the present invention. The SPF value evaluation method of the emulsion is based on the evaluation method of the sunscreen effect in the UVB area of ​​sunscreen cosmetics stipulated in QB / T 2410-1998 To operate, use an ordinary ultraviolet spectrophotometer as the ultraviolet light source, measure the ultraviolet absorbance A value of the sample in the UVB region (280-320nm), and judge the protective effect of the sample on UVB by comparing the absorbance of the sample. The emulsion is the emulsion prepared in Example 2 containing 1% of the extract of the pharmaceutical composition of the present invention.

[0047] result

[0048] Table 1 contains the ultraviolet absorption value of 1% pharmaceutical composition extract content emulsion of the present invention

[0049]

[0050]

[0051] It can be seen from Table 1 that the aver...

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Abstract

The invention discloses a pharmaceutical composition for sun protection and repairing and a preparation method and an application thereof. The pharmaceutical composition is characterized by being prepared from the following raw materials by mass: 290-310 parts of folium et ramulus evodiae, 200-360 parts of Japanese bugle herb, 140-160 parts of little-conical rabdosia herb, 140-160 parts of artemisia frigida, 140-160 parts of camellia nitidissima, 140-160 parts of semi-pinnated brake herb, 140-160 parts of ajuga ovalifolia var.calantha, and 140-160 parts of valeriana wallichii. The pharmaceutical composition has simple raw material acquisition and convenient preparation method. Clinical test results confirm that the pharmaceutical composition has good effect of sun protection and repairing,is easily accepted by consumers, and has good application prospects and market prospects.

Description

technical field [0001] The present invention relates to a pharmaceutical composition and its preparation method and application, in particular to a cosmetic pharmaceutical composition with sunscreen repairing effect and its preparation method and application. Background technique [0002] Ultraviolet wavelengths are divided into three sections: UVA, UVB and UVC. Among them, UVB is the mid-band ultraviolet region with a wavelength range of 280-320nm. It has the strongest effect on the skin and can enter the dermis to cause sunburn. UVA refers to the long-wave ultraviolet region, ranging from 320 to 400nm, which can pass through the dermis. The effect is slow, long-lasting, and cumulative. Over time, it will cause skin aging and increase the damage of UVB to the skin. UVC has weak penetrating power and will not cause harm to the skin. If there is no protective measures, the skin will be exposed to the sun for a long time, the surface will be red and swollen, burning pain, los...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/9749A61Q17/04A61Q19/00
CPCA61K8/9789A61K8/9749A61Q17/04A61Q19/004A61K2800/805
Inventor 王恩瀚陈汉坤郑洁瑜叶木英
Owner GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD