Electrophoretically-deposited carbon nano tube modified carbon fiber electrode and application thereof in in-vivo detection of ascorbic acid

Abstract

The invention discloses a new method used for modifying a carbon fiber electrode with carbon nano tubes. The method comprises the step of depositing single-walled carbon nano tubes on a carbon fiber electrode by adopting an electrophoretic deposition method, wherein electrophoretic deposition is realized by virtue of a two-electrode system, and the method comprises the following specific steps: inserting the carbon fiber electrode and a Pt wire into single-walled carbon nano tube dispersion, applying a voltage of 1.9-2.5V by virtue of amperometry and performing electrophoretic deposition for 10-100s, thus the carbon fiber electrode modified by the uniformly deposited carbon nano tubes can be obtained. Before in vivo analysis is performed, high temperature and electrochemical simple treatment is performed on the carbon nano tube modified carbon fiber electrode, so that the electrode can have high selectivity and sensitivity on ascorbic acid and can be used for in vivo intracerebral in situ determination on change of concentration of ascorbic acid.

Description

technical field [0001] The invention relates to an electrophoretic deposition carbon nanotube modified carbon fiber electrode and its application in the detection of living ascorbic acid. Background technique [0002] Ascorbic acid, also known as vitamin C, is an important neurochemical molecule in the brain. It mainly functions as an antioxidant and neuromodulator in the brain. Therefore, the change and accurate determination of ascorbic acid concentration are of great significance for the study of a series of physiological and pathological processes. . Among the various detection methods of ascorbic acid, the electrochemical method has attracted much attention due to its advantages of high temporal and spatial resolution, high sensitivity, and good selectivity. When the electrochemical method is used for in situ detection of the living body, carbon fiber electrodes with a thickness of about 7 μm are often used as probes, which cause less damage to the organism during real...

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Problems solved by technology

However, it is difficult for carbon nanotubes to be adsorbed on the surface of carbon fibers, and this method has high requirements for operation accuracy. It takes a long time of repeated operations to successfully modify carbon nanotubes on the electrode surface, and it is difficult to obtain an electrode with uniform thickness control of carbon nanotubes, resulting in The method of drop coating modification cannot easily and quickly obtain an electrode with high selectivity and reproducibility for the detection of ascorbic acid

At the same time, carbon fibers are easily broken during the modification process, resulting in a low yield of electrodes modified with carbon nanotubes.

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