Synthesis preparation method of pyruvate

Abstract

The invention discloses a synthesis preparation method of a pyruvate, and belongs to the chemical field. The synthesis preparation method comprises following steps: S10, a lactate s dissolved in a solvent so as to obtain a lactate solution; S20, a catalyst and an alkali are added into the lactate solution so as to obtain a semi-finished product; S40, the semi-finished product is subjected to filtering, and an obtained filtrate is collected; S50, the solvent is recycled, underpressure distillation is carried out, and distillation fractions are collected so as to obtain a finished product. According to the synthesis preparation method, no bromine or dangerous peroxide is adopted, and at the same time, no dangerous illumination operation is needed; reaction temperature is mild; after reaction, only filtering solid liquid separation is needed; no waste liquid is generated; after filtrate solvent recycling, high purify product can be obtained only through distillation; reaction conversion rate is 95% or higher; product GC purity is as high as 98% or higher; product yield is 90% or higher; safety risk is low; the synthesis preparation method is friendly to the environment, and is suitable for industrialized large scale production.

Description

Technical field [0001] The invention relates to the field of chemical engineering, in particular to a synthetic preparation method of pyruvate. Background technique [0002] Ethyl pyruvate is an important organic intermediate. Because of its bifunctional group and more reaction centers, it shows more important and special chemical properties than general compounds. Ethyl pyruvate is widely used in biology, medicine, food, perfume and cosmetics. Because of its active chemical properties, difficult preparation, and extremely wide and important uses, actively exploring new synthetic methods has become a hot spot for many chemists. [0003] The traditional synthesis process uses tartrate diester dehydration and decarboxylation to synthesize ethyl pyruvate, but this method has the characteristics of low yield, complex post-processing, and serious environmental pollution. Today, with the active development of "green chemistry", seeking a synthetic route with high yield, strong operabil...

AI Technical Summary

Problems solved by technology

[0003] The traditional synthesis process is to synthesize ethyl pyruvate by dehydration and decarboxylation of tartrate diester, but this method has the characteristics of low yield, complicated post-treatment, and serious environmental pollution.

With the active development of "Green Chemistry" today, seeking a high-yield, highly operable synthesis approach that conforms to the concept of "Green Chemistry" has become the direction that many chemists are actively pursuing. Certain defects, the main problem is that the additives added in the preparation process are not friendly to the environment, while the conversion rate of raw materials is low, and the purity is not ideal