9results about How to "Mild reaction temperature" patented technology

The invention relates to a preparation method of a baloxvir intermediate, and belongs to the technical field of medicine synthesis. The preparation method comprises the following steps: reacting a compound 02 with 2-fluorobenzaldehyde in the presence of an alkaline reagent, and carrying out post-treatment to obtain a compound 03. And carrying out cyclization reaction on the compound 03 in the presence of acid to obtain a compound 04. The preparation method provided by the invention is short in reaction time, mild in reaction, easy in reagent obtaining, safe to operate, high in product yield, high in product purity, capable of reducing the cost and beneficial to industrial implementation.

The application relates to the field of lithium ion battery electrolyte additives, in particular to a high-yield synthesis method of high-purity tris(trihydrocarbylsilyl)borate, and the synthesis steps are as follows: first, urea and hexahydrocarbyldisilazane are reacted to prepare hexahydrocarbyldisilourea; second, boric acid and the hexahydrocarbyldisilourea are reacted to obtain tris(trihydrocarbylsilyl)borate crude product; third, the crude product is purified to obtain high-purity tris(trihydrocarbylsilyl)borate. The synthesis method provided by the application has the advantages of high reaction conversion rate and yield, high product purity, recyclable filter residue and solvent after reaction, reduced waste emission and green and environment-friendly process.

The application discloses a preparation method of an enzyme-catalyzed bio-based nylon auxiliary, and belongs to the technical field of enzyme catalysis synthesis. Furan dicarboxylic acid dialkyl ester and tetramethyl piperidine amine are used as raw materials, and under the catalysis of an enzyme catalyst, the reaction is carried out in an organic solvent at a low reaction temperature. After the reaction is completed, the target product, bio-based nylon auxiliary N,N'-bis (2,2,6,6-tetramethyl-4-piperidyl) 2,5-furan dicarboxamide, is obtained by post-treatment of the reaction mixture. The method disclosed by the application does not involve high-risk and toxic reagents such as metal catalysts and alkalis. The method does not involve high-temperature conditions, the reaction temperature is 30 DEG C to 45 DEG C, the reaction temperature is mild and safe, and the requirement for equipment is low. The content of the obtained product on a gas chromatograph can reach more than 99%, and the yield can reach more than 95%.

The present application relates to solid waste resource utilization and environmental catalytic material technical field, disclose a kind of silicon carbide supported zero-valent iron type photocatalyst and its preparation method and application.The present application uses the crystal silicon recovered from waste photovoltaic panel and graphite recovered from waste lithium battery negative as raw material, under the condition without deep impurity removal purification, realizes solid phase activation and uniform mixing using mechanical chemical ball milling, and iron salt is added as iron source in the ball milling process, then low-temperature calcination is carried out to obtain silicon carbide supported zero-valent iron composite photocatalyst.The catalyst obtained by the present application has good light response and active site dispersion characteristics, and can be used for efficient degradation of metformin hydrochloride in water, and has the advantages of short preparation process, low cost, suitable for large-scale and high-value utilization of solid waste, etc.

The application discloses a zirconium-based porous metal organic framework catalyst, a preparation method and application. The catalyst is an MOF808 catalyst prepared from Zr salt and 1,3,5-benzene tricarboxylic acid in a molar ratio of 1:1. The catalyst, benzoic acid, benzylamine and a reaction solvent are placed in a reaction container, and an amine acid condensation reaction is carried out under nitrogen protection to obtain N-benzyl benzamide. The reaction temperature of the amine acid condensation reaction is 40-120 DEG C, and the reaction time is 2-24 h. The catalyst can efficiently and selectively condense benzoic acid and benzylamine to prepare N-benzyl benzamide under the condition that the reaction temperature is 90 DEG C and the solvent is tetrahydrofuran, and has the advantages of high conversion efficiency, good product selectivity, mild reaction condition, easy recycling and the like.

The invention provides a production process of norbornene, and belongs to the technical field of norbornene synthesizing.The production process comprises the steps that a dicyclopentadiene solution and ethylene are fed into a first radial tubular reactor to react, the reaction temperature is 200-280 DEG C, the reaction pressure is 4-10 MPa, the reaction time is 1-2 h, and the reaction time is 1-2 h; the retention time of the dicyclopentadiene solution and the ethylene is 0.1-2 hours; the materials are fed into a second radial tubular reactor for a reaction, the reaction temperature is 160-260 DEG C, the reaction pressure is 4-10 MPa, and the retention time is 0.1-1 h; carrying out gas-liquid separation and rectification separation to obtain norbornene; and the first radial tubular reactor and the second radial tubular reactor are filled with inert fillers. According to the invention, mixing and mass transfer are enhanced, the process flow time is shortened, the process severity is reduced, the reaction conditions are milder, and the operation cost is reduced.

The present application relates to the technical field of organic synthesis, and particularly relates to an environment-friendly synthesis method of 6-chloro-2-hydroxyquinolin. The specific scheme is that p-chloro-o-nitroacetacetanilide is closed under the action of a certain concentration of liquid alkali, electrolytic reduction is used instead of traditional reductant reduction to prepare a sodium salt, and the sodium salt is subjected to acidification treatment to obtain a pyridyl-quinoline intermediate (6-chloro-2-hydroxyquinolin). The method greatly reduces the discharge of sulfur-containing wastewater, has mild reaction conditions, short reaction period, protects the environment, and reduces the cost of synthesizing the pyridyl-quinoline intermediate (6-chloro-2-hydroxyquinolin).

The invention relates to the technical field of solid waste resource utilization and environmental catalytic materials, and discloses a silicon carbide loaded zero-valent iron type photocatalyst as well as a preparation method and application thereof. Crystalline silicon recycled from waste photovoltaic panels and graphite recycled from negative electrodes of waste lithium batteries are used as raw materials, solid-phase activation and uniform mixing are achieved through mechanochemical ball milling under the condition that deep impurity removal and purification are not conducted, and ferric salt is added in the ball milling process to serve as an iron source; and calcining at low temperature to obtain the silicon carbide loaded zero-valent iron composite photocatalyst. The obtained catalyst has good photoresponse and active site dispersion characteristics, can be used for efficient degradation of metformin hydrochloride in a water body, and has the advantages of being short in preparation process, low in cost, suitable for large-scale and high-value utilization of solid waste and the like.

This invention provides 13 High-abundance CO was prepared by CuO catalytic oxidation. 13 This invention relates to a CO2 apparatus and method, belonging to the field of stable isotope-labeled compound preparation technology. The apparatus described in this invention is an integrated unit comprising a feed gas supply unit, a fixed-bed reaction unit, a cryogenic collection unit, a partial pressure purification unit, and a tail gas treatment unit connected in series. The fixed-bed reaction unit includes a fixed-bed reactor, a heater, and a temperature sensor. This invention utilizes high-temperature calcined modified CuO catalyst particles, combined with a composite bed structure design of "quartz wool-quartz sand-catalyst-quartz sand," significantly improving conversion efficiency and selectivity; optimizing the purification process, achieving product quality that meets high-end application standards; featuring a novel apparatus design with greatly improved sealing and stability; simple and controllable operation, facilitating industrial scale-up; and being green, safe, and environmentally friendly, aligning with industrial development trends.