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Enzyme composition and application thereof in cosmetics with skin whitening function

A composition and enzyme technology, applied in cosmetics, cosmetic preparations, cosmetic preparations and other directions, can solve the problems of the inability of enzymes to function normally, the poor stability of enzyme cosmetics, and the slow onset of action, and achieve unique texture and product stability. Good, easily absorbed effect

Active Publication Date: 2019-08-13
湖南美媛本草生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Most of the existing enzyme cosmetics on the market are added with enzymes such as protease, yeast extract, yeast fermentation product and lactic acid bacteria fermentation product. Since enzymes are usually not as stable as other cosmetic raw materials, their activity is easily affected by acid, alkali, high temperature and surfactants. The impact of the enzyme cosmetics on the market makes the stability of the commercially available enzyme cosmetics poor, resulting in the inability of the enzyme to function normally, slow onset and other issues, which cannot meet the urgent needs of modern women to improve skin problems

Method used

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  • Enzyme composition and application thereof in cosmetics with skin whitening function
  • Enzyme composition and application thereof in cosmetics with skin whitening function
  • Enzyme composition and application thereof in cosmetics with skin whitening function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-7

[0038] The formula is shown in Table 1.

[0039]

[0040]

[0041] The method of the essence is specifically

[0042] (1) Mix and stir the rice fermentation product filtrate, the yeast polypeptide, the film-coated yeast fermentation product filter, the snow lotus fermentation broth, and the medicinal rhubarb extract in the formula amount at 25-35°C to prepare an enzyme composition;

[0043] (2) The formula amount of 1,2-pentanediol, 1,3-propanediol, betaine, trehalose, methyl glucitol-10, sodium polyglutamate, sodium hyaluronate, white fungus Mix the physical extract, disodium ethylenediaminetetraacetic acid and purified water, heat to 85-95℃, stir to dissolve, continue to keep warm and stir for 15-25min, then cool to 42-48℃, and then add the formula amount of enzyme combination in sequence Substances, tranexamic acid, rose water, nicotinamide, β-glucan, carboxymethyl chitosan, acetylhydroxyproline, nano-encapsulated ceramide, p-hydroxyacetophenone, stir and cool to 36-40℃ , Filter...

experiment example 1

[0060] Experimental example 1 whitening effect experiment

[0061] 1. Experimental population

[0062] 275 female volunteers aged 20-50 were selected and randomly divided into 11 groups with 25 volunteers in each group.

[0063] 2. Experimental equipment

[0064] German CK multi-probe skin test system MPA9, melanin and hemoglobin test probe (Mexamter MX18).

[0065] 3. Experimental method

[0066] After cleansing the face in the morning and evening, the subjects take 0.04ml (1ml=50 drops, that is, just take 2 drops), apply the whitening essence prepared in this example and the comparative example to the face, gently massage until absorbed, and try it for 28 days;

[0067] Before the test, the subjects need to clean their faces with clean water, wipe them clean with facial tissues, and sit quietly in a constant temperature and humidity laboratory (temperature 20±1°C, humidity 55±3) for 30 minutes before starting the measurement. Select the 4*4cm area in the middle of the right face of eac...

experiment example 2

[0076] Experimental example 2 Antibacterial performance test

[0077] Take 0.5 g of the whitening essence prepared in Example 1-5 and Comparative Example 4-5, add 10 ml of 55% by weight ethanol solution, stir and dissolve to obtain a sample solution, and store it for later use.

[0078] Preparation of test bacterial suspension: Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Candida albicans, Pseudomonas aeruginosa and Aspergillus niger were inoculated into test tube culture medium, incubated in a thermostat at 37°C for 48 hours and then added Aseptically treated distilled water, shake to obtain a suspension of experimental bacteria. Take 15ml of the melted SOB medium and place it in a sterilized petri dish, then add 1ml of experimental strains respectively, and make it flatten the bottom of the petri dish. After the medium is solidified, place 4 Oxford cups on each plate, and then add 0.1ml of plant-derived bacteriostatic agent solution. After culturing at 37°C for 24...

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Abstract

The invention discloses an enzyme composition and application thereof in cosmetics with a skin whitening function. The enzyme composition is prepared from, by weight, 2-3 parts of a rice fermentationproduct filtrate, 1.5-2.5 parts of yeast polypeptides, 2-3 parts of a film-coated yeast fermentation product filtrate, 0.1-2 parts of a saussurea involucrata fermentation liquor and 0.4-1.5 parts of amedicinal radix et rhizoma rhei extract. The invention also provides the application of the enzyme composition in preparation of the cosmetics with the skin whitening function. A skin whitening essence can be used for daily skin care and has the effects of whitening the skin, removing freckles, maintaining moisture, resisting and relieving inflammation and removing wrinkles. Meanwhile, the medicinal radix et rhizoma rhei extract and a saussurea involucrata extract in the saussurea involucrata fermentation liquor are adopted, so that the problem of inactivation when enzymes are combined with traditional chemical preservatives is solved, and the functional stability of a product is ensured.

Description

Technical field [0001] The invention belongs to the technical field of cosmetics, and specifically relates to an enzyme composition and its application in cosmetics with whitening functions Background technique [0002] Whitening has always been a topic of concern for beauty and personnel, and it is also a constant theme of cosmetics. In order to pursue the effect of rapid whitening, merchants add banned ingredients such as lead, mercury and hormones to their products. Although there will be obvious whitening effects in a short time after use, it will seriously harm the skin of consumers and is extremely difficult to cure. As my country's cosmetics regulations become more and more stringent, the addition of prohibited ingredients has been greatly reduced, and the harm caused by most whitening skin care products to consumers' skin has also been reduced, but the whitening effect is also greatly reduced. [0003] With the development of economy, the improvement of living standards, a...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9728A61K8/9789A61Q19/02A61Q19/00A61Q19/08
CPCA61K2800/85A61Q19/00A61Q19/02A61Q19/08A61K8/9728A61K8/9789A61K8/9794
Inventor 孙运文梁宗言
Owner 湖南美媛本草生物工程有限公司
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