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Fungistatic ginger-containing spray agent

A technology for inhibiting fungi and sprays, applied in antifungal agents, plant/algae/fungus/moss components, aerosol delivery, etc.

Inactive Publication Date: 2019-08-16
山东荆卫生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, in the process of research and development of new antifungal drugs, the development of new antibiotics not only eliminates drug-resistant fungi, but also screens drug-resistant fungi. However, the speed of developing new antibiotics is far behind that of fungal drug-resistant bacteria. The footsteps, resulting in the quiet emergence of "super bacteria" that most antibacterial drugs can't kill

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0036] Take 25 parts of ginger, 15 parts of aloe vera, 15 parts of Chrysanthemum chrysanthemum, 10 parts of honeysuckle, 10 parts of tangerine peel, 10 parts of peppercorns, and 10 parts of cassia seeds. Water was sorted and rinsed for 1 hour, and dried for later use.

[0037] After crushing 25 parts of ginger with a mortar, extract with 20 times the volume of 95% ethanol at 97°C for 1 hour, filter and concentrate at 50°C to obtain gingerol extract.

[0038] Put 15 parts of fresh aloe into a juice extractor, use 15 volumes of water as the extract, and filter the residue with sterilized gauze to obtain the aloe extract.

[0039] After crushing 15 parts of white chrysanthemum with a mortar, extract with 15 times the volume of absolute ethanol for 1 hour, filter and concentrate at 50°C to obtain a white chrysanthemum alcohol extract.

[0040] Grinding the above-mentioned honeysuckle, tangerine peel, Chinese prickly ash and cassia seeds into powder, decocting with 10 times the volu...

example 2

[0047] Take 22 parts of ginger, 11 parts of aloe vera, 13 parts of Chrysanthemum chrysanthemum, 5 parts of honeysuckle, 8 parts of tangerine peel, 9 parts of peppercorns, and 7 parts of cassia seeds, and carry out net selection respectively to pick out the defective medicinal materials; Water was sorted and rinsed for 1 hour, and dried for later use.

[0048] After crushing 22 parts of ginger with a mortar, extract with 20 times the volume of 95% ethanol at 97°C for 1 hour, filter and concentrate at 50°C to obtain gingerol extract.

[0049] Put 11 parts of fresh aloe into a juice extractor, use 15 volumes of water as the extract, and filter the residue with sterilized gauze to obtain the aloe extract.

[0050] After crushing 13 parts of Chrysanthemum chrysanthemum with a mortar, extract it with 15 times the volume of absolute ethanol for 1 hour, filter and concentrate at 50°C to obtain the alcohol extract of Chrysanthemum chrysanthemum.

[0051] Grinding the above-mentioned h...

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PUM

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Abstract

The invention mainly relates to the technical field of innovative drug research and development, and discloses a drug spray agent which can inhibit the growth of fungi so as to achieve the treatment of fungal dermatosis. The invention aims to provide a traditional Chinese medicine bacteriostatic spray agent for fungal dermatosis, wherein the traditional Chinese medicine bacteriostatic spray agentis prepared by extracting effective ingredients from a natural traditional Chinese medicine plant formula by a modern pharmaceutical technology. The spray agent comprises the following raw materials in parts by weight: 20-25 parts of a raw ginger extract liquid, 10-15 parts of an aloe extract liquid, 10-15 parts of a chrysanthemum morifolium extract liquid, 5-10 parts of pericarpium citri reticulatae, 5-10 parts of Sichuan pepper, 5-10 parts of honeysuckle, and 5-10 parts of semen cassiae. The drug has the functions of breaking walls and penetrating muscles, expelling toxin, and preventing andtreating fungal dermatosis. With traditional Chinese medicine extraction, the spray agent can avoid drug resistance, quickly kill pathogenic bacteria, avoid recurrence and alleviate patient pain, andhas no toxic or side effects and almost no harm to skin; a variety of plant traditional Chinese medicine ingredients can be antibacterial and bacteriostatic, and the device is quite convenient to spray and does not affect travel.

Description

technical field [0001] The invention relates to the field of drugs for treating fungal skin diseases, in particular to a ginger-containing spray for inhibiting fungi. Background technique [0002] The alcoholic extract of ginger contains 6-gingerol, curcumin and other chemical components that can inhibit the survival of fungi and kill fungi to a certain extent, and have various medicinal values. Studies have shown that ginger extract is inhibitory to Gram-positive bacteria, has strong toxicity to Salmonella, and strongly inhibits Staphylococcus aureus and Escherichia coli. Fungi such as Fusarium moniliforme and Fusarium graminearum all have a certain inhibitory effect. Ginger can play the role of some antibiotics, especially for a variety of bacteria, and also has a significant effect of inhibiting skin fungi and killing Trichomonas vaginalis Efficacy, can inhibit capillary permeability, reduce swelling and analgesia, and have obvious promotion effect on wound healing. It ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/12A61P17/00A61P31/10
CPCA61K9/0014A61K9/12A61K36/287A61K36/355A61K36/482A61K36/752A61K36/758A61K36/886A61K36/896A61K36/9068A61K2236/33A61K2236/331A61P17/00A61P31/10A61K2300/00
Inventor 林思妮董红宇吴东颖
Owner 山东荆卫生物科技有限公司
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