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Semen cuscutae ultrafine powder preparation method of utilizing semen cuscutae to process spermatogenesis tablets

A technology of Cuscuta superfine powder, which is applied in the field of preparation of Cuscuta superfine powder, can solve the problems of reducing the therapeutic effect of spermatogenic tablets, uneven color of coated tablets, and rough surface of coated tablets, so as to improve bioavailability and facilitate absorption , smooth surface effect

Inactive Publication Date: 2019-09-06
GUIZHOU LIANSHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The existing preparation process of spermatozoa is to directly grind the medicinal material of Cuscuta officinalis through 80 meshes and then use it to make glue. It is difficult to break the filaments with a general pulverizer, which will directly affect the coating effect of the subsequent process, resulting in cracking or breaking of the coating film, rough surface of the coated tablet, uneven color of the coated tablet, etc.
Not only caused a large waste of dodder resources, but also reduced the therapeutic effect of spermatogenic tablets

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A method for preparing Cuscuta superfine powder by using Cuscuta to process spermatogenesis sheet, said method mainly comprising the following steps:

[0020] (1) Raw material preparation: After washing and drying the raw material of dodder seed, it is set aside;

[0021] (2) Mechanical pulverization: Put the dried dodder raw material into a pulverizer, and carry out a wall-breaking pulverization under normal temperature conditions until the particle size is 20-30 mesh, and the small dodder raw material that cannot pass through is returned to the pulverizer again , pulverized again under the same conditions until all passed through the sieve to obtain coarse powder particles of dodder;

[0022] (3) Drying treatment: dry the coarse powder particles obtained after mechanical pulverization, and adopt low-temperature freeze-drying treatment to carry out drying treatment, first undergo low-temperature embrittlement treatment, and then carry out vacuum drying treatment, the l...

Embodiment 2

[0026] A method for preparing Cuscuta superfine powder by using Cuscuta to process spermatogenesis sheet, said method mainly comprising the following steps:

[0027] (1) Raw material preparation: After washing and drying the raw material of dodder seed, it is set aside;

[0028] (2) Mechanical pulverization: Put the dried dodder raw material into a pulverizer, and carry out a wall-breaking pulverization under normal temperature conditions until the particle size is 20-30 mesh, and the small dodder raw material that cannot pass through is returned to the pulverizer again , pulverized again under the same conditions until all passed through the sieve to obtain coarse powder particles of dodder;

[0029] (3) Drying treatment: dry the coarse powder particles obtained after mechanical pulverization, and adopt low-temperature freeze-drying treatment to carry out drying treatment, first undergo low-temperature embrittlement treatment, and then carry out vacuum drying treatment, the l...

Embodiment 3

[0033] A method for preparing Cuscuta superfine powder by using Cuscuta to process spermatogenesis sheet, said method mainly comprising the following steps:

[0034] (1) Raw material preparation: After washing and drying the raw material of dodder seed, it is set aside;

[0035] (2) Mechanical pulverization: Put the dried dodder raw material into a pulverizer, and carry out a wall-breaking pulverization under normal temperature conditions until the particle size is 20-30 mesh, and the small dodder raw material that cannot pass through is returned to the pulverizer again , pulverized again under the same conditions until all passed through the sieve to obtain coarse powder particles of dodder;

[0036] (3) Drying treatment: dry the coarse powder particles obtained after mechanical pulverization, and adopt low-temperature freeze-drying treatment to carry out drying treatment, first undergo low-temperature embrittlement treatment, and then carry out vacuum drying treatment, the l...

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Abstract

The invention relates to a semen cuscutae ultrafine powder preparation method of utilizing semen cuscutae to process spermatogenesis tablets. The preparation method mainly includes: preparing raw materials, mechanically smashing, drying, performing primary ultrafine smashing, and performing secondary ultrafine smashing. Different smashing modes are adopted for wall-breaking smashing, drying is performed, airflow-type ultrafine smashing is performed twice, and fine powder obtained after smashing is applied in the spermatogenesis tablets, so that the problem that existing spermatogenesis tabletsare poor in film forming performance and big and uniform in film gap is solved, treatment effect of drug can be improved, absorption of the drug is facilitated, active ingredients that cannot be fully absorbed or utilized previously can be reutilized, and bioavailability of semen cuscutae and utilization rate of raw materials are improved. A product prepared by the method is high in film formingperformance and small and uniform in film gap, coated tablets are smooth in surface and uniform in color, and the product is exquisite in quality and free of granular sensation; byproducts produced byheat generation during smashing are reduced, so that cost of the product is lowered.

Description

technical field [0001] The invention belongs to the technical field of powder production in traditional Chinese medicine preparations, and in particular relates to a method for preparing superfine powder of dodder by using dodder to process spermatozoa. Background technique [0002] Testicular spermatogenesis dysfunction is the primary cause of male infertility, manifested as oligospermia, weak sperm or even azoospermia. Oligospermia refers to too few sperm in the semen, and its pathogenesis is related to spermatogenesis and maturation disorders caused by damage to the testis and epididymis. At present, although there are many types of drugs on the market for improving male sexual function and anti-fatigue, they generally contain hormone substances or are added with carrier substances that increase penetration. If patients take the former for a long time, it will cause endocrine disorders. The latter is bound to damage the body if it takes too long. Therefore, the use of p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/39A61K36/43A61K9/14A61P15/08A61P15/10A61P13/00A61P1/14
CPCA61K9/14A61K36/39A61K36/43A61P1/14A61P13/00A61P15/08A61P15/10
Inventor 杜平
Owner GUIZHOU LIANSHENG PHARMA
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