Medical scar-repairing silicone gel dressing and preparation method thereof

Abstract

The invention relates to the technical field of dressings, in particular to a medical scar-repairing silicone gel dressing and a preparation method thereof. The medical scar-repairing silicone gel dressing is made from, by weight, 5-30% of polydimethylsiloxane, 3-20% of an emulsifier, 0.5-5% of substrate gel, 1-15% of a scar fading factor, 0.01-0.5% of a deodorizer, 0.05-5% of an antibacterial agent, 5-10% of an antipruritic, 0.0001-0.1% of an anti-contracture drug, 0.05-10% of a penetration promoter, and the balance of a buffer solution system and purified water. The anti-contracture drug made with plant extracts, corticosteroid hormones, heparin sodium, papaverine hydrochloride and other smooth muscle relaxation drugs is embedded in gel, the smooth muscle relaxation drugs are absorbed bythe human body through transdermal absorption, excess contraction of myofibroblasts is inhibited, the force of scar contracture is lessened, and scar contracture is prevented accordingly.

Description

technical field [0001] The invention relates to the technical field of dressings, in particular to a silicone gel dressing for medical scar repair and a preparation method thereof. Background technique [0002] Due to burns, burns, crushing injuries, electric shocks, surgery and other causes of injury, scars are likely to remain after treatment for wounds with a depth of more than two degrees, and the hyperplasia of the remaining scars often leads to deformities. Scar contractures and deformities caused by deep burns on the hands Often cause hand dysfunction, bring inconvenience to patient's life and work. [0003] Most existing anti-scar contracture methods are oral anti-contracture drugs or compression methods for prevention. It is not suitable for children and other patients who have poor self-control and cannot take medicine on time and often use their hands. Another example is that the patent No. CN207684095U discloses a scar The repair gel is characterized in that it ...

AI Technical Summary

Problems solved by technology

[0002] Due to burns, burns, crushing injuries, electric shocks, surgery and other causes of injury, scars are likely to remain after treatment for wounds with a depth of more than two degrees, and the hyperplasia of the remaining scars often leads to deformities. Scar contractures and deformities caused by deep burns on the hands It often causes hand dysfunction and brings inconvenience to the life and work of patients

[0003] Most existing anti-scar contracture methods are oral anti-contracture drugs or compression methods for prevention. It is not suitable for children and other patients who have poor self-control and cannot take medicine on time and often use their hands. Another example is that the patent No. CN207684095U discloses a scar The repair gel is characterized in that it is made of the following raw materials in parts by weight: 0.03-0.05 parts of heparin sodium, 0.04-0.06 parts of hyaluronic acid, 0.04-0.06 parts of aloe powder, 0.04-0.06 parts of grape seed extract, vitamin E0.05-0.15 parts, lavender oil 0.05-0.15 parts, bisabolol 0.12-0.25 parts, nicotinamide 0.35-0.7 parts, carbomer 0.6-0.8 parts, allantoin 0.8-1.3 parts, centella asiatica extract 0.8-1.3 parts of substance, 5-6.8 parts of glycerin, 1-1.4 parts of solubilizer, 0.2-0.8 parts of neutralizer, 0.05-0.15 parts of essence, 0.25-0.35 parts of preservative, 85-91 parts of water, but scar repair effect Not good, can not be effectively promoted