Preparation method and use of polysaccharide of radix millettiae speciosae

Abstract

The invention discloses a preparation method and use of polysaccharide of radix millettiae speciosae, relates to a natural product polysaccharide, and aims to solve the problems of low yields and unsatisfied purities as required for drugs and health care product additives for extraction processes of polysaccharide of radix millettiae speciosae in the prior art. The preparation method comprises thefollowing steps: (1) subjecting radix millettiae speciosae powder to supercritical CO2 extraction to obtain a radix millettiae speciosae extract; (2) soaking the extract in water of equal weight, wherein a complex enzyme accounting for 0.5-1.0% of the raw materials by mass is added to the water, and proportions of the components in the complex enzyme are as follows: cellulase:xylanase:protease =(1-3):(3-1):(2-4); (3) subjecting the enzymolysis mixture from the step (2) to continuous countercurrent extraction with water to obtain an extract; (4) after filtering the extract to remove impurities, adsorbing the extract by using a macroporous resin, filtering the extract, retaining the entrapped liquid, and concentrating the entrapped liquid in vacuum to 10-20% of the original volume; and (5)drying: drying the entrapped concentrate, thereby obtaining the polysaccharide of radix millettiae speciosae. The polysaccharide of radix millettiae speciosae obtained by the preparation method can used in production of medicaments for treating acute lung injury.

Description

technical field [0001] The present invention relates to the preparation and application of natural product polysaccharides, more specifically, to a preparation method and application of bovine herbaceous polysaccharides. Background technique [0002] Niu Dali (Millettia Speciosa Champ.) is the dry tuberous root of Millettia Speciosa Champ., a plant in the Fabaceae Papilionaceae subfamily, which is widely planted in Guangdong and Guangxi. It is often used in medicinal food and medicinal wine. It has the effect of relieving cough and clearing lung. It is a famous medicinal and edible plant in Lingnan area. Niu Dali has been used as the main raw material in the production of various Chinese patent medicines such as Qiangli Fitness Capsules, and is clinically used to treat chronic diseases such as pneumonia, chronic bronchitis, physical weakness after illness, and lumbar muscle strain. Niu Dali has the functions of nourishing and clearing the lungs and has remarkable effects in...

AI Technical Summary

Problems solved by technology

The yields of these polysaccharides from Niu Dali are low, and the purity is not up to the requirements of medicines or health care product additives. Therefore, to explore a kind of extraction technology with higher yield and purity of polysaccharides from Niu Dali is very important for the development of Niu Dali polysaccharides. A precious Chinese herbal medicine resource, it is very important to improve its application value