Unlock instant, AI-driven research and patent intelligence for your innovation.

Method for controllable catalysis of ring-opening polymerization of o-carboxylic acid anhydride monomer based on Lewis acid-base system of metal salt and organic base

A technology of ring-opening polymerization and metal salt, which is applied in the field of polyester synthesis, can solve the problems of no controllability and achieve the effect of high molecular weight

Active Publication Date: 2020-07-24
BEIJING UNIV OF CHEM TECH
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Organic bases are often used to catalyze the ring-opening polymerization of lactone monomers, but these organic bases do not show controllability in the process of catalyzing the ring-opening polymerization of OCA monomers due to epimerization

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for controllable catalysis of ring-opening polymerization of o-carboxylic acid anhydride monomer based on Lewis acid-base system of metal salt and organic base
  • Method for controllable catalysis of ring-opening polymerization of o-carboxylic acid anhydride monomer based on Lewis acid-base system of metal salt and organic base
  • Method for controllable catalysis of ring-opening polymerization of o-carboxylic acid anhydride monomer based on Lewis acid-base system of metal salt and organic base

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Under a nitrogen atmosphere at room temperature, add 2 equivalents of zinc acetate, 2 equivalents of DBU, 1 equivalent of benzyl alcohol and 1 mL of anhydrous dichloromethane solution into the reaction tube, mix and stir for 10 minutes, then add 50 equivalents of PheOCA monomer, and wait for 3 hours to After the solid conversion rate reaches more than 95%, the reaction solution is precipitated in a mixed solvent of ether, n-hexane and methanol to obtain a white polymer. Gel permeation chromatography (GPC) result shows that gained polymer molecular weight M n =9.9KDa, molecular weight distribution

Embodiment 2

[0039] Under a nitrogen atmosphere at room temperature, add 2 equivalents of zinc chloride, 2 equivalents of DBU, 1 equivalent of benzyl alcohol and 1 mL of anhydrous dichloromethane solution into the reaction tube, mix and stir for 10 minutes, then add 50 equivalents of PheOCA monomer, and wait for 2 hours After the monomer conversion rate reaches over 95%, the reaction solution is precipitated in a mixed solvent of ether, n-hexane and methanol to obtain a white polymer. Gel permeation chromatography (GPC) result shows that gained polymer molecular weight M n =12.6KDa, molecular weight distribution

Embodiment 3

[0041] Under a nitrogen atmosphere at room temperature, add 2 equivalents of zinc bromide, 2 equivalents of DBU, 1 equivalent of benzyl alcohol and 1 mL of anhydrous dichloromethane solution into the reaction tube, mix and stir for 10 minutes, then add 50 equivalents of PheOCA monomer, and wait for 4 hours After the monomer conversion rate reaches over 95%, the reaction solution is precipitated in a mixed solvent of ether, n-hexane and methanol to obtain a white polymer. Gel permeation chromatography (GPC) result shows that gained polymer molecular weight M n =9.2KDa, molecular weight distribution

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
molecular weightaaaaaaaaaa
molecular weightaaaaaaaaaa
molecular weightaaaaaaaaaa
Login to View More

Abstract

The invention discloses a method for controllably catalyzing ring opening polymerization of an O-carboxylic acid anhydride monomer based on a Lewis acid-base system containing a metal salt and an organic base, and belongs to the technical field of polyester synthesis. Under nitrogen protection, at room temperature and in an anhydrous solvent, the Lewis acid-base system consisting of the metal saltand the organic base catalyzes controllable ring-opening polymerization of the OCA monomer by adopting alcohol or an amine as an initiator, the molecular weight of the obtained polymer can reach 20.8KDa, the molecular weight distribution index is less than 1.20, and the stereoregularity Pm of the polymer can reach 0.88. The metal salt and the organic base can be commercially purchased, the Lewisacid-base catalytic system can be used only by simply mixing a zinc salt and the organic base, and the operation is convenient and efficient.

Description

technical field [0001] The invention belongs to the technical field of polyester synthesis. Specifically, it relates to a new method for controllably catalyzing the ring-opening polymerization of O-carboxylic acid anhydride monomers by a Lewis acid-base system composed of a metal salt and an organic base. The metal salts and organic bases used can be purchased commercially, and the catalytic system is simple, easy to obtain, stable and efficient. Background technique [0002] Petroleum-based polymers derived from fossil energy are difficult to recycle due to their non-degradable properties, causing environmental pollution. Poly(α-hydroxy acids) (PAHAs), as a class of biodegradable and biocompatible polyester compounds, have been widely used in biomedical devices, packaging materials, drug delivery and other fields. Poly(α-hydroxy acids) with side chain functional groups have excellent mechanical and physicochemical properties. Poly(α-hydroxy acids) are traditionally obtai...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08G63/83C08G63/87C08G63/00
CPCC08G63/00C08G63/823
Inventor 杨晶王佩
Owner BEIJING UNIV OF CHEM TECH