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Nutritional support fat component formula for tumor patients and preparation method of microcapsule powder thereof

A technology for cancer patients and nutrition, which is applied in the field of nutritional food for cancer patients, can solve problems such as unsatisfactory effects, failure to consider the nutritional needs and nutritional risks of cancer patients, and achieve the effect of increasing the burden on the liver and improving the metabolic state

Inactive Publication Date: 2020-02-11
上海张新生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, in the current market, the traditional microencapsulated powder used to treat tumor patients does not take into account the nutritional needs and nutritional risks of tumor patients, so the effect achieved after eating is not very ideal

Method used

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  • Nutritional support fat component formula for tumor patients and preparation method of microcapsule powder thereof
  • Nutritional support fat component formula for tumor patients and preparation method of microcapsule powder thereof
  • Nutritional support fat component formula for tumor patients and preparation method of microcapsule powder thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] 1. Pre-experiment: Screen suitable experimental mice and find out the appropriate dosage of chemotherapeutic drugs;

[0059] 2. Formal experiment:

[0060] (1) Sample preparation:

[0061] Proportion of fat component 1: Weigh 40kg of fish oil into the blender, turn on the blender, add 35 grams of antioxidant natural vitamin E, 15 grams of tea polyphenols, 10 grams of rosemary extract, and 18 grams of bamboo leaf antioxidants Stir well to make refined fish oil. Add 35kg of whey protein, 23.922kg of isomaltooligosaccharide, and 1kg of sunflower oil phospholipids to the prepared refined fish oil in turn, stir and mix well, add water at a rate of 0.8Kg / min while stirring until the emulsion becomes transparent The emulsion is spray-dried through a spray tower, the drying air temperature is 120°C, and the air outlet temperature is 40°C, and the fish oil microcapsule powder with stable properties is obtained after packaging.

[0062] The ratio of 2 of the fat component is: ...

Embodiment 2

[0070] (1) Sample preparation

[0071] Proportion of fat component 1: Weigh 40kg of fish oil into the blender, turn on the blender, add 35 grams of antioxidant natural vitamin E, 15 grams of tea polyphenols, 10 grams of rosemary extract, and 18 grams of bamboo leaf antioxidants Stir well to make refined fish oil. Add 35kg of whey protein, 23.922kg of isomaltooligosaccharide, and 1kg of sunflower oil phospholipids to the prepared refined fish oil in turn, stir and mix well, add water at a rate of 0.8Kg / min while stirring until the emulsion becomes transparent The emulsion is spray-dried through a spray tower, the drying air temperature is 120°C, and the air outlet temperature is 40°C, and the fish oil microcapsule powder with stable properties is obtained after packaging.

[0072] The ratio of 2 of the fat component is: Weigh 18 kilograms of olive oil, 16 kilograms of sunflower oil and 15.999 kilograms of medium-chain MCT into the mixer, turn on the mixer, add 1 gram of antiox...

Embodiment 3

[0079] By analyzing the difference in glycemic index between the embedding wall materials developed by this application and the common wall materials on the market, the analysis of this

[0080] Effects of nutritional interventions in R&D products.

[0081] 3.1. Sample preparation

[0082] Prepare wall material sample A (technical method of this application to embed wall material-protein type wall material)

[0083] 2.5kg of whey protein, 2.396kg of isomaltooligosaccharide, 0.1kg of sunflower oil phospholipids, and 4 grams of tea polyphenols are prepared into wall material sample A

[0084] Preparation of wall material sample B (commercially available wall material embedded in a common method-glucose type wall material)

[0085] 4kg of glucose syrup, 0.62KG of sodium caseinate, 0.08KG of sodium ascorbate, 0.1KG of phospholipids, and 0.2KG of mono- and di-fatty acid glycerides are configured into wall material sample B

[0086] 3.2. Experimental design

[0087]Set the conve...

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Abstract

The invention discloses a nutritional support fat component formula for tumor patients and a preparation method of microcapsule powder of the nutritional support fat component formula. The nutritionalsupport fat component formula comprises 20 to 60 parts of grease, 10 to 40 parts of isomalto-oligosaccharide, 10 to 40 parts of whey protein, 0.5 to 10 parts of an emulsifier and 0.01 to 5 parts of an antioxidant, wherein the grease comprises one or a compound mixture of more than one of medium-chain triglyceride, olive oil, sunflower seed oil, fish oil and silybum marianum seed oil. The nutritional support fat component formula for tumor patients and the preparation method of the microcapsule powder of the nutritional support fat component formula have the beneficial effects that (1) effective energy support can be provided for the tumor patients quickly, the metabolic state of malignant consumption of the tumor patients is improved, the formula is rich in monounsaturated and polyunsaturated fatty acids, the liver burden is not increased, and chronic inflammatory signs can be intervened after the formula is used for a long time; and (2) the wall material is relatively low in glycemicindex, cane sugar and glucose are not used, the flavor is good and the embedding effect is good.

Description

technical field [0001] The invention relates to the technical field of nutritional food for tumor patients, in particular to a fat component formula for nutritional support of tumor patients and a preparation method thereof for microcapsule powder. Background technique [0002] Tumor cells mainly meet their energy needs through glucose, while the utilization of fatty acids and ketone bodies is very low. Based on this principle, in order to adapt to the metabolic changes of tumor patients, the energy supply ratio of fat and carbohydrates can be adjusted. Appropriate high-fat diet can maintain body weight and cell mass. A study of patients undergoing chemotherapy for gastrointestinal cancers showed that those who received a conventional diet lost weight, while those who received an appropriate high-fat diet, especially with monounsaturated fatty acids as the main energy source, gained weight and maintained body cell mass throughout the study Stablize. [0003] Fat emulsion ...

Claims

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Application Information

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IPC IPC(8): A23L33/12A23L33/115A23L29/00A23L29/30A23P10/30
CPCA23V2002/00A23L29/035A23L29/045A23L29/05A23L29/30A23L33/115A23L33/12A23P10/30A23V2200/222A23V2200/224A23V2200/32A23V2250/18A23V2250/1944A23V2250/21A23V2250/2132A23V2250/214A23V2250/28A23V2250/54252A23V2250/712
Inventor 陶杨张天宏吴超
Owner 上海张新生物医药科技有限公司
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