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Fat component formula for nutritional support of tumor patients and preparation method of microcapsule powder of fat component formula

A tumor patient and nutrition technology, applied in the field of nutritious food for tumor patients, can solve the problem that the effect is not ideal, the nutritional needs and nutritional risks of tumor patients are not considered, and the effect of increasing the burden on the liver and improving the metabolic state is achieved.

Pending Publication Date: 2020-12-15
上海张新生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, in the current market, the traditional microencapsulated powder used to treat tumor patients does not take into account the nutritional needs and nutritional risks of tumor patients, so the effect achieved after eating is not very ideal

Method used

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  • Fat component formula for nutritional support of tumor patients and preparation method of microcapsule powder of fat component formula
  • Fat component formula for nutritional support of tumor patients and preparation method of microcapsule powder of fat component formula
  • Fat component formula for nutritional support of tumor patients and preparation method of microcapsule powder of fat component formula

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] 1. Pre-experiment: Screen suitable experimental mice and find out the appropriate dosage of chemotherapeutic drugs;

[0052] 2. Formal experiment:

[0053] (1) Sample preparation:

[0054] Proportion of fat component 1: Weigh 40kg of fish oil into the blender, turn on the blender, add 35 grams of antioxidant natural vitamin E, 15 grams of tea polyphenols, 10 grams of rosemary extract, and 18 grams of bamboo leaf antioxidants Stir well to make refined fish oil. Add 35kg of whey protein, 23.922kg of isomaltooligosaccharides, and 1kg of sunflower oil phospholipids to the prepared refined fish oil in turn, stir and mix well, add water at a rate of 0.8Kg / min while stirring, until the emulsion becomes transparent The emulsion is spray-dried through a spray tower, the drying air temperature is 120°C, and the air outlet temperature is 40°C, and the fish oil microcapsule powder with stable properties is obtained after packaging.

[0055] The ratio of 2 of the fat component is...

Embodiment 2

[0072] (1) Sample preparation

[0073] Proportion of fat component 1: Weigh 40kg of fish oil into the blender, turn on the blender, add 35 grams of antioxidant natural vitamin E, 15 grams of tea polyphenols, 10 grams of rosemary extract, and 18 grams of bamboo leaf antioxidants Stir well to make refined fish oil. Add 35kg of whey protein, 23.922kg of isomaltooligosaccharides, and 1kg of sunflower oil phospholipids to the prepared refined fish oil in turn, stir and mix well, add water at a rate of 0.8Kg / min while stirring, until the emulsion becomes transparent The emulsion is spray-dried through a spray tower, the drying air temperature is 120°C, and the air outlet temperature is 40°C, and the fish oil microcapsule powder with stable properties is obtained after packaging.

[0074] The ratio of 2 of the fat component is: Weigh 18 kg of olive oil, 16 kg of sunflower oil and 15.999 kg of medium-chain MCT into the blender, turn on the blender, add 1 gram of antioxidant natural v...

Embodiment 3

[0092] (2) By analyzing the difference in glycemic index between the embedding wall materials developed by this application and the common wall materials available in the market, the effect of nutritional intervention of this research and development product is analyzed.

[0093] Set the negative control group, positive control group (conventional wall material system), the embedding system of this application, and set three gradients of 0.2mg, 0.4mg, and 0.6mg / mouse / time for the embedding system of this application, under the condition of overnight fasting , First measure the fasting blood glucose, and then measure the blood glucose 15min, 30min, 45min, 60min, 90min, 120min after eating.

[0094] The results obtained are as follows:

[0095]

[0096]

[0097] Table 6 Blood glucose testing data

[0098] At the dose of 0.2g and 0.4g, there was no significant difference between the glucose wall material and the protein wall material on the blood sugar of mice, but at the ...

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Abstract

The invention discloses a preparation method of microcapsule powder of a fat component formula for nutritional support of tumor patients. The microcapsule powder comprises grease, isomalto-oligosaccharide, whey protein, an emulsifier and an antioxidant, wherein the grease comprises 20-60 parts of grease, 10-40 parts of isomalto-oligosaccharide, 10-40 parts of whey protein, 0.5-10 parts of the emulsifier and 0.01-5 parts of the antioxidant; the grease comprises one or a compound mixture of more than one of medium chain triglyceride, olive oil, sunflower seed oil, fish oil and silybum marianum seed oil. The microcapsule powder has the benefits as follows: (1) the microcapsule powder can provide effective energy support for the tumor patients quickly, improve the malignant consumption metabolic state of the tumor patients, is rich in monounsaturated and polyunsaturated fatty acids, does not increase the burden of the liver and can intervene chronic inflammatory signs after long-term use;and (2) the wall material has a lower glycemic index, no sucrose or glucose is used, the flavor is good, and the embedding effect is good.

Description

technical field [0001] The invention relates to the technical field of nutritional food for tumor patients, in particular to a fat component formula for nutritional support of tumor patients and a preparation method thereof for microcapsule powder. Background technique [0002] Tumor cells mainly meet their energy needs through glucose, while the utilization of fatty acids and ketone bodies is very low. Based on this principle, in order to adapt to the metabolic changes of tumor patients, the energy supply ratio of fat and carbohydrates can be adjusted. Appropriate high-fat diet can maintain body weight and cell mass. A study of patients undergoing chemotherapy for gastrointestinal cancers showed that those who received a conventional diet lost weight, while those who received an appropriate high-fat diet, especially with monounsaturated fatty acids as the main energy source, gained weight and maintained body cell mass throughout the study Stablize. [0003] Fat emulsion ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/12A23L33/115A23L29/00A23L29/30A23P10/30
CPCA23L33/12A23L33/115A23L29/045A23L29/035A23L29/05A23L29/30A23P10/30A23V2002/00A23V2200/222A23V2200/224A23V2200/32A23V2250/18A23V2250/1944A23V2250/21A23V2250/2132A23V2250/214A23V2250/28A23V2250/54252A23V2250/712
Inventor 陶杨张天宏吴超
Owner 上海张新生物医药科技有限公司
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