A method for determining main sweeteners in edible flavors and fragrances by hplc-ms/ms
A technology for food flavors and sweeteners, applied in the field of physical and chemical index detection of food additives, can solve the problems of matrix interference, low detection accuracy, complex components, etc., and achieve the effects of high sensitivity, good repeatability, and strong anti-matrix interference ability
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[0042] 1. Instruments and reagents
[0043] Xylitol, acesulfame potassium, sodium saccharin, sodium cyclamate, sucralose, aspartame, neohesperidin, neotame
[0044] Standard samples of 9 sweeteners such as stevioside and stevia; methanol, ethanol, ammonium acetate (all of which are chromatographically pure); meet the requirements of first-class water in GB / T6682.
[0045] 6460 HPLC-MS / MS mass spectrometer (Agilent, USA), TM-1 vortex mixer (Wuxi
[0046]Woxin Instrument Co., Ltd.); KQ-500DE ultrasonic generator (Kunshan Ultrasonic Instrument Co., Ltd.); electronic balance (METTLER TOLEDO company, with a sense of 0.1 mg); 50 mL centrifuge tube (corning company, PP material).
[0047] 2. Preparation of matrix solvent
[0048] Choose one that does not contain xylitol, acesulfame potassium, sodium saccharin, sodium cyclamate, sucralose, aspartame,
[0049] For the edible flavors of 9 sweeteners such as neohesperidin, neotame and stevia, accurately weigh 0.5201 g of the sample, a...
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