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Compound bactericide with broad-spectrum bactericidal effect

A fungicide and compound technology, applied in the field of daily chemical product manufacturing, can solve the problems of inability to disinfect the application of products and high cost of natural essential oils

Pending Publication Date: 2020-04-03
NORTHEAST NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, natural essential oils are expensive in production and cannot be used in disinfection products

Method used

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  • Compound bactericide with broad-spectrum bactericidal effect
  • Compound bactericide with broad-spectrum bactericidal effect
  • Compound bactericide with broad-spectrum bactericidal effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1, the antibacterial activity research of compound bactericide

[0021] Step 1, the formula of compound fungicide

[0022] We have formulated a series of compound fungicides based on the main components of plant essential oils. After antibacterial and antibacterial susceptibility tests, we determined the best compound fungicide formula.

[0023] The compound fungicide is composed of the following ingredients in percentage by weight: 40%-50% of linalool, 18%-25% of terpineol, 8%-15% of geraniol, and 2% of beta-cyclocitral -4%, nerol 2.5%-5%, myrcene 1-3%, ocimene 1-3%, ionone 3-6%, 2H-β-ionone 5-8%. The specific composition is shown in Table 1.

[0024] Table 1 Composition of compound fungicides

[0025]

[0026]

[0027] Step 2, the antibacterial activity assay of compound fungicide

[0028] 2.1 Preparation of medium

[0029] Bacterial culture uses LB medium: to prepare per liter of medium, add: tryptone 10g, yeast extract 5g, sodium chloride 10g ...

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Abstract

The invention provides a compound bactericide with bacteriostatic or bactericidal activity. The composition comprises, by weight, 40% to 50% of linalool, 18% to 25% of terpilenol, 8% to 15% of geraniol, 2% to 4% of beta-cyclocitral, 2.5% to 5% of nerol, 1% to 3% of myrcene, 1% to 3% of ocimene, 3% to 6% of ionone and 5% to 8% of 2H-beta-ionone. Antibacterial and bacteriostatic drug sensitivity tests show that the bactericide artificially prepared on the basis of natural essential oil components has a broad-spectrum inhibition effect on bacteria and fungi. The bactericide has bacteriostatic andbactericidal effects on bacteria (escherichia coli, bacillus subtilis, staphylococcus aureus, staphylococcus epidermidis and the like) and fungi (candida albicans, Schlechospora crassa, trichophytonrubrum, saccharomyces cerevisiae and the like), and particularly has an obvious effect on zoonosis. The bactericide can be applied to development of zoonosis infection and other sterilization products.

Description

technical field [0001] The invention belongs to the field of manufacture of daily chemical products, and in particular relates to a compound bactericide with broad-spectrum bactericidal effect. Background technique [0002] Infectious diseases caused by pathogenic microorganisms such as bacteria, fungi and viruses are still a serious threat to human health, and some of them are difficult to completely control . According to statistics, there are about 16 million patients who die from microbial infection every year in the world, accounting for about 1 / 3 of the total number of deaths. Bacteria and fungi are ubiquitous in nature, most of which are directly or indirectly beneficial to humans, but a few species are harmful to the environment, humans and animals. In recent years, with the improvement of people's living standards, pets and other companion animals have gradually entered people's lives, and the number has increased significantly. While bringing joy to humans, they ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/045A61K31/11A61K31/01A61K31/12A61P31/02A61P31/04A61P31/10A61P31/12
CPCA61K31/045A61K31/11A61K31/01A61K31/12A61P31/02A61P31/04A61P31/10A61P31/12A61K2300/00Y02A50/30
Inventor 王丽高翔
Owner NORTHEAST NORMAL UNIVERSITY
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