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Method for preparing oral liquid capable of preventing and treating gout from alkaloids of alkali-tolerant rice

A gout oral liquid and alkaloid technology, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of unsatisfactory curative effect of gout prevention and treatment, low purity of alkaloid extraction, restore human body function, and facilitate large-scale industrialization The effect of low production and production costs

Inactive Publication Date: 2020-04-10
好当家集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to overcome the disadvantages of low purity of extracted alkaloids and unsatisfactory curative effect on gout prevention and treatment in the prior art, the object of the present invention is to provide an alkali-grown rice with high purity, high extraction rate, reasonable preparation and good curative effect. Method for preparing alkaloid oral liquid for preventing and treating gout

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A method for preparing an oral liquid for preventing and treating gout with alkaline rice alkaloids, which comprises the following process steps:

[0030] (1) Preparation of alkaline rice alkaloids:

[0031] ①Raw material pretreatment: select dry alkali-grown rice, pulverize it with an ultrafine pulverizer, add deionized water for wetting, wherein, the weight ratio of ultrafinely pulverized alkali-grown rice and deionized water is 1:0.3; Put the alkali rice material into the steam explosion tank for steam explosion wall breaking treatment for 6 minutes, and the conditions of steam explosion are: pressure 1.5Mpa, pressure maintenance time 7s; then add the alkali rice material after steam explosion wall breaking treatment It is 25% ethanol solution, and the alkali-growing rice material and ethanol solution after the steam explosion wall breaking treatment are mixed evenly in a ratio of 1:4 by mass, and set aside;

[0032] ②Fermentation: Weigh the mixed material obtained ...

Embodiment 2

[0040] A method for preparing an oral liquid for preventing and treating gout with alkaline rice alkaloids, which comprises the following process steps:

[0041] (1) Preparation method of alkaline rice alkaloids

[0042] ①Raw material pretreatment: select dry alkali-grown rice, pulverize it with an ultrafine pulverizer, add deionized water for wetting, wherein, the weight ratio of ultrafinely pulverized alkali-grown rice and deionized water is 1:0.2; The alkali rice material was put into the steam explosion tank for steam explosion wall breaking treatment for 5 minutes. The steam explosion conditions were: pressure 1Mpa, pressure maintenance time 10s; 20% ethanol solution, the alkali-growing rice material and ethanol solution after its steam explosion wall breaking process are mixed uniformly in the ratio of mass ratio 1: 5, for subsequent use;

[0043] ②Fermentation: Weigh the mixed material obtained in step ①, and add a compound strain of 2% of the weight of the blended mat...

Embodiment 3

[0051] A method for preparing an oral liquid for preventing and treating gout with alkaline rice alkaloids, which comprises the following process steps:

[0052] (1) Preparation method of alkaline rice alkaloids

[0053] ①Raw material pretreatment: select dry alkali-grown rice, pulverize it with an ultrafine pulverizer, add deionized water for wetting, wherein, the weight ratio of ultrafinely pulverized alkali-grown rice and deionized water is 1:0.5; Put the alkali-grown rice material into the steam explosion tank for steam explosion wall breaking treatment for 8 minutes. The steam explosion conditions are: pressure 1.8Mpa, pressure maintenance time 5s; It is 35% ethanol solution, and the alkali-growing rice material and ethanol solution after its steam explosion wall breaking process are mixed uniformly in a ratio of 1:3 by mass, and are set aside;

[0054] ②Fermentation: Weigh the mixed material obtained in step ①, and add a compound strain of 5% of the weight of the blende...

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Abstract

The invention relates to a method for preparing oral liquid capable of preventing and treating gout from alkaloids of alkali-tolerant rice. The method solves the problems of low purity of extracted alkaloids and low curative effect in prevention and treatment of gout in the prior art. The method comprises the following steps: (1) preparing alkaloids of alkali-tolerant rice; (2) preparing a soup base; (3) mixing raw materials; and (4) preparing a finished oral liquid. According to the method, the alkali-tolerant rice is pretreated by using a steam explosion technology and is fermented, acidified and dissolved by alcohol, so the extraction rate of alkaloids of the alkali-tolerant rice is increased; a fermentation technology is cooperatively utilized to break the walls of epidermis-protectedinternal parenchyma cells or vacuoles, so the alkaloids are more fully exposed; a supercritical carbon dioxide technology and a membrane technology are combined to refine the extract, so micromolecular vegetable protein and pigment are effectively removed, and product purity is greatly improved; and the alkaloids of alkali-tolerant rice are matched with coix seeds, kudzuvine roots, pagodatree flower buds, poria cocos, semen cuscutae and dunaliella salina to obtain the oral liquid which has the effects of dredging purine synthesis and metabolism, reducing uric acid and repairing liver and kidney functions and is good in treatment effect.

Description

technical field [0001] The invention relates to a medical preparation containing plants, especially a method for preparing an oral liquid for preventing and treating gout with alkaline rice alkaloids. Background technique [0002] With the development of my country's economy, the consumption of seafood in the residents' diet has increased, and the number of purines in the human body has increased sharply. The final metabolite of purines is uric acid. In the normal human physiological environment, 98% of uric acid exists in the form of urate ions. , when the sodium urate concentration is higher than 380 μmol / L, it may cause sodium monourate to crystallize or have a risk of precipitation, causing gout, and gout has a tendency to become younger. For gout, there are many medicines and health foods that exclude purines to treat gout on the market. These chemical or biological products have the potential to cause kidney damage and have little effect. There is an urgent need for an ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P19/06
CPCA61K9/0095A61K36/05A61K36/076A61K36/39A61K36/43A61K36/488A61K36/489A61K36/899A61K36/8994A61K2236/15A61K2236/19A61K2236/331A61K2236/37A61P19/06A61K2300/00
Inventor 孙永军鞠文明唐晓波王淑倩毕囡囡邱美茹王鹏程彭莉晶
Owner 好当家集团有限公司
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