Preparation method of low-sugar type ferrum-folic acid tablet

A technology of iron folic acid and sugar form, which is applied in the field of preparation of low-sugar iron folic acid tablets, can solve problems such as poor taste, high sugar content of iron folic acid tablets, and difficulty in absorbing, and achieve a reasonable formula, easy disintegration, and unbreakable Effect

Inactive Publication Date: 2020-05-26
HUANGGANG HUAYANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current iron folic acid tablets have high sugar content, poor taste, and are not easy to absorb after entering the stomach, so it needs to be solved urgently.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A kind of preparation method of low-sugar type iron folic acid tablet that the present invention proposes, comprises the following steps:

[0018] S1. Mix ferrous fumarate, ferrous gluconate, folic acid compound and edible corn starch evenly to obtain a premix;

[0019] S2. Mix mint, sodium carboxymethyl starch, maltodextrin, and microcrystalline cellulose evenly, add premix and magnesium stearate, mix evenly, and press into tablets to obtain low-sugar iron folic acid tablets.

Embodiment 2

[0021] A kind of preparation method of low-sugar type iron folic acid tablet that the present invention proposes, comprises the following steps:

[0022] S1. Mix 30 parts of ferrous fumarate, 15 parts of ferrous gluconate, 2 parts of folic acid compound, and 100 parts of edible corn starch in parts by weight to obtain a premix;

[0023] S2. Mix 1 part of mint, 4 parts of sodium carboxymethyl starch, 1 part of maltodextrin, and 4 parts of microcrystalline cellulose in parts by weight, add 120 parts of premix and 3 parts of magnesium stearate, mix uniformly, press Tablets to get low-sugar iron folic acid tablets.

Embodiment 3

[0025] A kind of preparation method of low-sugar type iron folic acid tablet that the present invention proposes, comprises the following steps:

[0026] S1. Mix 40 parts of ferrous fumarate, 5 parts of ferrous gluconate, 8 parts of folic acid compound, and 60 parts of edible corn starch in parts by weight to obtain a premix;

[0027] The folic acid complex is prepared by the following process: mix folic acid, cholesterol, Tween 80, and egg yolk lecithin evenly, add absolute ethanol to stir, add phosphate buffer, continue stirring, evaporate to remove ethanol, cool, add carboxymethyl cellulose Sodium, homogeneously processed to obtain folic acid complex;

[0028] S2. Mix 4 parts of peppermint, 2 parts of sodium carboxymethyl starch, 2 parts of maltodextrin, and 2 parts of microcrystalline cellulose in parts by weight, add 140 parts of premix and 1 part of magnesium stearate, mix evenly, and press Tablets to get low-sugar iron folic acid tablets.

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PUM

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Abstract

The invention discloses a preparation method of a low-sugar type ferrum-folic acid tablet. The preparation method comprises the following steps: uniformly mixing ferrous fumarate, ferrous gluconate,a folic acid compound and edible corn starch to obtain a premix; and uniformly mixing mint, sodium carboxymethyl starch, maltodextrin and microcrystalline cellulose, adding the premix and magnesium stearate, uniformly mixing, and tabletting to obtain the low-sugar ferrum-folic acid tablet. The folic acid compound is prepared by adopting the following process: uniformly mixing folic acid, cholesterol, Tween 80 and egg yolk lecithin, adding absolute ethyl alcohol, stirring, adding a phosphate buffer solution, continuously stirring, evaporating to remove ethyl alcohol, cooling, adding sodium carboxymethyl cellulose, and homogenizing to obtain the folic acid compound. The obtained ferrum-folic acid tablets are good in taste and extremely low in sugar content, are easy to disintegrate after entering intestines and stomachs, are easier to digest and absorb by human bodies, can effectively supplement folic acid and iron, have the effects of refreshing breath and promoting oral health afterbeing eaten, and overcome the defects of similar products on the market at present.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a preparation method of low-sugar iron folic acid tablets. Background technique [0002] Iron folic acid tablet is a kind of nutritional supplement, suitable for pregnant women and pregnant women. Folic acid can promote the development of nerve cells and brain cells in infants. Lack of folic acid can easily lead to fetal neural tube development defects, and increase the risk of split brain and anencephaly. Folic acid supplementation is necessary in the pre-pregnancy and early stages, which can help prevent the occurrence of fetal neural tube defects. Folic acid can promote the absorption of iron and prevent the unsuitable phenomenon of single iron supplementation. However, the current iron folic acid tablets have high sugar content, poor taste, and are difficult to absorb after entering the stomach, which needs to be solved urgently. Contents of the invention [0...

Claims

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Application Information

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IPC IPC(8): A23L33/15
CPCA23L33/15A23V2002/00A23V2250/7056
Inventor 张龑
Owner HUANGGANG HUAYANG PHARMA
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