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Traditional Chinese medicine extract with soothing and anti-inflammatory effect, preparation method and application thereof

A technology of extracts and traditional Chinese medicines, which is applied in the field of traditional Chinese medicine extracts with soothing and anti-inflammatory effects and its preparation and application. It can solve the problems of skin irritation and poor anti-stimulating effects, and achieve easy operation, enhanced skin barrier function, and inhibition of hyaluronic acid. Effect of Acidase Activity

Active Publication Date: 2021-07-27
四川启燃科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] One of the objectives of the present invention is to provide a traditional Chinese medicine extract with soothing and anti-inflammatory effects in order to solve the shortcomings of existing anti-allergic substances, such as poor anti-allergic effect and irritation to the skin

Method used

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  • Traditional Chinese medicine extract with soothing and anti-inflammatory effect, preparation method and application thereof
  • Traditional Chinese medicine extract with soothing and anti-inflammatory effect, preparation method and application thereof
  • Traditional Chinese medicine extract with soothing and anti-inflammatory effect, preparation method and application thereof

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Effect test

Embodiment 1

[0059] The preparation of embodiment 1 Chinese medicine extract

[0060] The Shumin anti-inflammatory traditional Chinese medicine prescription is calculated by weight, and the ratio is 6 parts of Rhizome, 5 parts of Arrowhead mushroom, 2 parts of Duhuo, 2 parts of Sanleng, 1 part of baby tea, and 1 part of Polygala.

[0061] Feeding according to the ratio of material to liquid is 1:8, that is, add 50g of Chinese medicine powder and 400mL of ethanol solution with a volume fraction of 80% in a round bottom flask. ; Heating and reflux extraction at 50°C for 120min; stop heating, cool to 40°C, fine filter with filter plate, filter with diatomaceous earth; take the filtrate, add activated carbon with 1% of the filtrate mass for decolorization, the decolorization temperature is 50°C, and the decolorization time is 120min, Finely filter the filter plate, concentrate the filtrate at 40°C and 0.07MPa under reduced pressure until the feed liquid has no obvious ethanol smell, and obtain...

Embodiment 2

[0062] The preparation of embodiment 2 Chinese medicine extract

[0063] The Shumin anti-inflammatory traditional Chinese medicine prescription is calculated by weight, and the ratio is 8 parts of Rhizome, 6 parts of Arrowhead mushroom, 3 parts of Duhuo, 3 parts of Sanleng, 2 parts of baby tea, and 2 parts of Polygala.

[0064] Feed according to the ratio of material to liquid at 1:15, that is, add 50g of Chinese medicine powder and 750mL of ethanol solution with a volume fraction of 70% in a round bottom flask. ; Heating and reflux extraction at 60°C for 180min; stop heating, cool to 35°C, fine filter with filter plate, filter with diatomaceous earth; take the filtrate, add 2% activated carbon of the filtrate mass for decolorization, the decolorization temperature is 70°C, and the decolorization time is 80min, Finely filter the filter plate, concentrate the filtrate at 45°C and 0.07MPa under reduced pressure until the feed liquid has no obvious ethanol smell, and obtain the e...

Embodiment 3

[0065] The preparation of embodiment 3 Chinese medicine extracts

[0066] The Shumin anti-inflammatory traditional Chinese medicine prescription is calculated by weight, and the ratio is 7 parts of Cyanorrhizae, 5.5 parts of Arrowhead mushroom, 2.5 parts of Duhuo, 2.5 parts of Sanleng, 1.5 parts of baby tea, and 1.5 parts of polygala.

[0067] Feed according to the ratio of material to liquid at 1:20, that is, add 50g of Chinese medicine powder and 1000mL of ethanol solution with a volume fraction of 80% in a round bottom flask. Heating and reflux extraction at 75°C for 150min; stop heating, cool to 50°C, fine filter with filter plate, filter with diatomaceous earth; take the filtrate, add 2% activated carbon of the filtrate mass for decolorization, the decolorization temperature is 80°C, and the decolorization time is 120min, filter Finely filter the plate, concentrate the filtrate at 50°C and 0.07MPa under reduced pressure until the feed liquid has no obvious ethanol smell, ...

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Abstract

The invention discloses a traditional Chinese medicine extract with soothing and anti-inflammation effects and its preparation method and application. The traditional Chinese medicine extract is made of the following raw materials in proportions by weight: 6-8 parts of Rhizoma chinensis, 5-8 parts of Arrowhead mushroom 6 servings, 2-3 servings of Duhuo, 2-3 servings of Sanleng, 1-2 servings of Baby Tea, 1-2 servings of Polygala. Its preparation method comprises the following steps: (1) after pulverizing the traditional Chinese medicine of the prescription, heating and extracting in ethanol solution; (2) cooling, filtering, decolorizing, fine filtering, and taking fine filtrate for later use; (3) step (2) The filtrate is concentrated to obtain the Chinese medicine extract extract; (4) The Chinese medicine extract extract in step (3) is mixed and dissolved with polyols, and filtered to obtain the Chinese medicine extract with soothing and anti-inflammatory effects. The traditional Chinese medicine extract provided by the invention has various functions such as inhibiting hyaluronidase activity, scavenging free radicals, anti-inflammatory and anti-allergic, enhancing skin barrier function, etc., and can be widely used in various skin medical supplies such as creams and daily chemical products. middle.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract with soothing and anti-inflammatory effects, a preparation method and application thereof. Background technique [0002] An allergic reaction is an abnormal or pathological reaction of the human body to an antigen. In the process of allergic reaction, the allergen (antigen) plays a direct role and is the external cause of the allergic reaction; while the body's immunity is low, and the oxidative damage of cells by a large number of free radicals is the internal cause of the allergic reaction. Skin allergy is a relatively common skin problem. With the increase in the use of skin medicine products, daily chemical products and other chemicals, environmental problems, the accelerated pace of life in modern society, and increased pressure, there are more and more people with sensitive skin. . Coupled with some people's improper use of skin care products and other reasons, it is often easy to ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9794A61K8/9789A61K36/902A61P37/08A61P29/00A61P17/18A61Q19/00A61Q19/08
CPCA61K9/0014A61K36/232A61K36/48A61K36/53A61K36/69A61K36/898A61K36/902A61K2236/333A61K2236/51A61K2800/592A61K2800/782A61K2800/805A61Q19/00A61Q19/005A61Q19/08A61K8/9789A61K8/9794A61P17/18A61P29/00A61P37/08A61K2300/00
Inventor 王领刘佳伟杨效登李天铎苗颖慧
Owner 四川启燃科技开发有限公司