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Light-controlled liquid drop movement method, light-controlled liquid drop movement micropipe and manufacturing method of light-operated liquid drop movement micropipe

A liquid droplet motion and microtube technology, applied in the direction of fluid flow, engine components, mechanical equipment, etc., can solve the problems of practical limitations, freedom of movement restrictions, and free control of droplets that cannot be batched, so as to improve practicality, Wide variety of effects with fast drive speed

Active Publication Date: 2020-06-09
WESTLAKE UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, this kind of microtube actuator realizes the movement control of droplets in a closed tube, and its freedom of movement is limited. For example, this kind of microtube actuator cannot use light-controlled droplets to complete micro-scale multi-level biochemical reactions; and , the batch of liquid droplets cannot be freely manipulated in this closed execution tube, so it cannot be applied to batch liquid control, that is to say, the driving of the microtube actuator is accomplished by changing the diameter of the actuator , the diameter of the same executive tube will change uniformly, resulting in the inability to freely manipulate multiple droplets at the same time; of course, the controllable and effective release and separation of droplets cannot be achieved, so its practicability is also limited to a certain extent

Method used

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  • Light-controlled liquid drop movement method, light-controlled liquid drop movement micropipe and manufacturing method of light-operated liquid drop movement micropipe
  • Light-controlled liquid drop movement method, light-controlled liquid drop movement micropipe and manufacturing method of light-operated liquid drop movement micropipe
  • Light-controlled liquid drop movement method, light-controlled liquid drop movement micropipe and manufacturing method of light-operated liquid drop movement micropipe

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0084] Preparation Example 1 Preparation of microtubes for light-controlled droplet movement

[0085] 1. Prepare the wall material of the light-controlled droplet movement microtube:

[0086] The specific preparation method is as follows:

[0087] 1.1 Synthesis of epoxy cyclooctene:

[0088] Dissolve chloroperoxybenzoic acid in chloroform and add dropwise to the flask containing 1,5-cyclooctadiene. After the dropwise addition, stir at room temperature and filter to remove the white precipitate. Sodium bisulfate aqueous solution, sodium bicarbonate aqueous solution and sodium chloride aqueous solution are washed, and vacuum distillation obtains epoxy cyclooctene;

[0089] 1.2 Synthesis of 5-hydroxy-1-cyclooctene:

[0090]Add the anhydrous tetrahydrofuran solution of lithium aluminum hydride, dissolve the epoxidized cyclooctene in tetrahydrofuran, and add the anhydrous tetrahydrofuran solution dropwise under the protection of argon. Water terminates the reaction. The result...

Embodiment 1

[0108] Example 1 Light-controlled droplet motion microtube drives droplet motion by changing the curvature of the outer wall

[0109] Both ends of the light-controlled liquid droplet movement microtube (with an inner diameter of 0.1 mm and an outer diameter of 0.11 mm) prepared in Preparation Example 1 were fixed. Use a micropipette to suspend 0.5 µL of silicone oil on the wall of the microtube. A light source is placed above the light-controlled droplet movement microtube, and an attenuation filter is placed between the light source and the light-control droplet movement microtube to generate attenuated light. Turn on the light source, the light source intensity is 100-120mW / cm -2 ;

[0110] Results: The outer wall of the microtubules produces asymmetric curvature changes, driving the droplet to move along the direction of light attenuation. The movement process is as follows: figure 1 shown.

Embodiment 2

[0111] Example 2 Light-controlled droplet movement microtube controls the direction of droplet movement by changing the curvature of the outer wall

[0112] The experiment of Example 1 was repeated, except that when the capillary was irradiated with light, the placement direction of the attenuation sheet was changed, that is, the attenuation direction of light was adjusted.

[0113] It was found that the droplet on the wall of the microtubules changes the direction of movement, and the movement process is as follows: figure 2 As shown, see the movement process from 0 seconds to 7 seconds to 8 seconds to 16 seconds.

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Abstract

The invention relates to a light-controlled liquid drop movement method, a light-controlled liquid drop movement micropipe and a manufacturing method of the light-operated liquid drop movement micropipe. The technology utilizes the gradient change of the curvature of the outer wall caused by the asymmetrical deformation of the light-controlled liquid drop movement micropipe to induce laplace pressure difference to be generated so as to drive a liquid drop to move. By the adoption of the light-controlled liquid drop movement method, the light-controlled liquid drop movement micropipe and the manufacturing method of the light-operated liquid drop movement micropipe, liquid drops of various polarities and components can be driven, it can also be achieved that the liquid drops are driven to conduct stirring, mixing, transmitting tiny objects and other liquid drop operations, even the liquid drops can be driven to conduct multi-grade chemical reactions, and the light-controlled liquid dropmovement method has great application potential in the fields of microreactors, micromechanical systems, chip laboratories, trace liquid conveyance, biomedical devices, water collecting devices and the like.

Description

technical field [0001] The invention belongs to the technical field of optically controlled liquid droplets, and in particular relates to a method for optically controlled liquid droplet movement, a micropipe for optically controlled liquid droplet movement and a manufacturing method thereof. Background technique [0002] The technology of light-controlled droplet motion in an open environment is of great significance for both basic scientific research and industrial applications. However, due to the resistance of the three-phase contact line, the current photo-controlled droplet movement technology in an open environment, whether it is the photo-induced wettability gradient or the Marangoni effect, can only drive a few liquid crystals, oleic acid, olive oil, etc. Several special types of droplets, and the driving speed is less than 0.3mm / s (Lab Chip, 2012, 12, 3637), but the liquids commonly used in biochemical laboratories cannot be effectively driven, which cannot meet th...

Claims

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Application Information

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IPC IPC(8): F15D1/06
CPCF15D1/007F15D1/0085F15D1/06F16K99/00
Inventor 吕久安胡志明
Owner WESTLAKE UNIV
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