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Production process of Zushima joint analgesic plaster

A production process and technology of analgesic ointment, which is applied in the field of production technology of Zushima joint analgesic ointment, to achieve the effect of less allergic reaction, lower energy consumption, and product safety

Pending Publication Date: 2020-07-28
甘肃祖师麻制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide a "hot pressing method" production process of Zushima joint pain relief cream, so as to completely eliminate the flammable, explosive and environmental pollution problems existing in the existing "solvent method" production process production regulations of this product. Hidden dangers and defects

Method used

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  • Production process of Zushima joint analgesic plaster
  • Production process of Zushima joint analgesic plaster
  • Production process of Zushima joint analgesic plaster

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Raw material ratio: Zushima liquid extract 1310g, camphor 88.3g, borneol 88.3g, menthol 99.7g, methyl salicylate 77.3g, diphenhydramine 7.7g, xylene musk 37.7g;

[0081] Ratio of matrix auxiliary materials: natural rubber 5346g, vaseline 1420g, lanolin 570g, rosin 2878g, zinc oxide 5170

[0082] Lining material: cloth (width 86cm) 103m; cover lining material: paper / methicone (width 110mm) 7200g

[0083] The process provided in this embodiment is realized through the following implementation steps and methods.

[0084] Rubber drying and cutting: Wash the rubber with drinking water first, put it in a hot air circulation oven, dry it at 50℃~60℃, cut it into thin slices or strips, and set aside.

[0085] Rosin crushing: crush the rosin into coarse particles and set aside.

[0086] Rubber plastication: add rubber into the rubber mixer and refine it into silk floc.

[0087] Ingredients: Qualified rubber, rosin, zinc oxide, vaseline, lanolin, and borneol, camphor, menthol, ...

Embodiment 2

[0104] Except that there are differences in the following composition ratios, all the other features are the same as in Example 1.

[0105] Ratio of matrix auxiliary materials: natural rubber 5480g, vaseline 1420g, lanolin 570g, rosin 2740g, zinc oxide 5170

[0106] Lining material: cloth (width 86cm) 103m; cover lining material: paper / methicone (width 110mm) 7200g

experiment example

[0108] Volatile component borneol, menthol content determination contrasts in the sample that this process invention and former process (solvent method) produce:

[0109] Statistical Analysis of Volatile Component Borneol Content in the Samples Produced by the Process Invention and the Original Process (Solvent Method) in Table 1

[0110]

[0111] Table 2 Statistical analysis of volatile component menthol content in the sample produced by this process invention and former process (solvent method)

[0112]

[0113]

[0114]This process invention compares the content determination of zumarin and methyl salicylate in the sample produced by the original process (solvent method):

[0115] Table 3 Statistical analysis of the contents of zumarin and methyl salicylate in the samples produced by this process invention and the original process (solvent method)

[0116]

[0117] This process invention and the sample that former process (solvent method) produces in the ancest...

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PUM

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Abstract

The invention relates to a production process of Zushima joint analgesic plaster. The production process comprises steps as follows: rubber is heated, softened and plastified to be flocculent; the flocculent rubber, Vaseline and wool fat are heated and mixed untile the rubber sufficiently absorbs the vaseline and the wool fat, wherein 30-40 parts by weight of the rubber, 6-12 parts by weight of the vaseline and 2-5 parts by weight of the wool fat are added sequentially; second mixing is performed and plastification is performed until the rubber materials are uniform and have basically consistent color and luster; the mixed rubber materials and rosin are mixed uniformly: the obtained materials are mixed uniformly with a Zushima fluid extract and pharmaceutic adjuvants, and the pharmaceuticadjuvants contain active ingredients easily volatilizing when heated; the materials and a filling dispersant are mixed uniformly; the mixture is applied and rolled, drying is not performed after application; and the process does not contain the step of adding solvent gasoline to soak the rubber. Compared with conventional processes, the production process is safer, and the prepared product is better in quality.

Description

technical field [0001] The invention relates to the technical field of production of rubber plaster preparations, in particular to a production process of Zushima Joint Pain Relief Ointment. Background technique [0002] Zushi Ma Joint Pain Relief Ointment is a rubber plaster, which has a history of more than 40 years of preparation and application. [0003] The existing production process of Zushima Joint Pain Relief Ointment is the "solvent method" production process, that is, the natural rubber is washed, dried, cut into strips, put into a rubber mixer to refine into silk flocs, and added with No. 120 solvent Soak in gasoline, and when it swells into a gel, put it in a glue machine and stir evenly, then add zinc oxide, rosin, vaseline, and lanolin in sequence, and continue stirring until it is evenly mixed. Add methyl sylate, diphenhydramine, and musk xylene into the glue machine and stir to make a uniform paste, then move it into the glue filter, filter it with an 80-me...

Claims

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Application Information

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IPC IPC(8): A61K36/83A61K9/70A61P29/00A61P19/02
CPCA61K9/7076A61K36/83A61P19/02A61P29/00
Inventor 张春云毛著鸿王家强
Owner 甘肃祖师麻制药有限公司
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