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Composition and preparation method and application thereof

A composition and mixture technology, applied in the directions of botanical equipment and methods, applications, chemicals for biological control, etc., can solve the problems of mammalian poisoning, chromosome aberration, human and animal harm, etc., and achieve easy industrialization and expansion of production. Accessible, low-cost effects

Active Publication Date: 2020-12-04
JIANGSU UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these substances are harmful to humans and animals while preventing and treating stiff diseases, and there is a risk of polluting the environment
For example, although carbendazim can prevent and treat stiffness, its residues can cause liver disease and chromosomal aberrations, and are toxic to mammals

Method used

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  • Composition and preparation method and application thereof
  • Composition and preparation method and application thereof
  • Composition and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 Preparation of antibacterial substances for preventing and treating silkworm morbidity

[0042] Step (1): After the wheat bran is dried at 70-80°C, it is beaten into wheat bran powder, and passed through a 30-mesh sieve for later use;

[0043] Step (2): extract the wheat bran powder in step (1) with 95% ethanol for 24 hours each time, and repeat the extraction for 2 times with irregular shaking during the period;

[0044] Step (3): Separate the ethanol extract from the wheat bran by filtration, combine the filtrates, and concentrate under reduced pressure to obtain a viscous ethanol extract, wherein the concentration under reduced pressure is at -0.08MPa and placed in a 60°C water bath Concentration process;

[0045] Step (4): extracting the ethanol extract with petroleum ether, each extraction is 15min, repeated twice, and combining the petroleum ether extracted each time;

[0046] Step (5): Concentrating the petroleum ether phase under reduced pressure to ...

Embodiment 2

[0052] Embodiment 2 Preparation of antibacterial substances for preventing and treating silkworm morbidity

[0053] Step (1): After the wheat bran is dried at 70-80°C, it is beaten into wheat bran powder, and passed through a 40-mesh sieve for later use;

[0054] Step (2): extract the wheat bran powder in step (1) with 95% ethanol for 24 hours each time, and repeat the extraction for 3 times with irregular shaking during the period;

[0055] Step (3): Separate the ethanol extract from the wheat bran by filtration, combine the filtrates, and concentrate under reduced pressure to obtain a viscous ethanol extract, wherein the concentration under reduced pressure is at -0.08MPa and placed in a 55°C water bath Concentration process;

[0056] Step (4): using petroleum ether to extract the ethanol extract, each extraction is 20min, repeated 3 times, and the petroleum ether extracted each time is combined;

[0057] Step (5): Concentrating the petroleum ether phase under reduced pres...

Embodiment 3

[0063] Example 3 Preparation of antibacterial substances for preventing and treating silkworm morbidity

[0064] Step (1): After the wheat bran is dried at 70-80°C, it is beaten into wheat bran powder, and passed through a 40-mesh sieve for later use;

[0065] Step (2): extract the wheat bran powder in step (1) with 95% ethanol for 24 hours each time, and repeat the extraction for 3 times with irregular shaking during the period;

[0066] Step (3): Separate the ethanol extract from the wheat bran by filtration, combine the filtrates, and concentrate under reduced pressure to obtain a viscous ethanol extract, wherein the concentration under reduced pressure is at -0.08MPa and placed in a 50°C water bath Concentration process;

[0067] Step (4): using petroleum ether to extract the ethanol extract, each extraction is 30min, repeated 3 times, and the petroleum ether extracted each time is combined;

[0068] Step (5): Concentrating the petroleum ether phase under reduced pressur...

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Abstract

The invention discloses a composition. The composition is prepared from, by mass percentage, 20-40% of a wheat bran extract, 4-8% of a solubilizer, 0-0.4% of an adhesive and the balance water. The invention also discloses a preparation method and application of the composition. The prevention substance provided by the invention can be applied to silkworms to prevent the silkworms from being infected with muscardine diseases. The raw materials are easy to obtain, and the composition is low in cost, easy to process, and suitable for industrial production. Particularly, compared with traditionaldrugs for preventing silkworm muscardine diseases, the composition has the advantages of being poisonless and harmless and environmentally friendly; and meanwhile, the wheat bran is recycled, and thesustainable development of agriculture is facilitated.

Description

technical field [0001] The invention belongs to the fields of biotechnology and pesticide and veterinary medicine, and in particular relates to a composition and its preparation method and application. Background technique [0002] Silkworm stiffness is one of the main diseases in silkworm breeding and production, which is caused by fungus parasitism. Silkworm morbidity includes beauveria, yellow stiffness, metaborrhea, etc. Sericulture in rural areas is mainly caused by beauveria. Because of its strong infectivity, it is necessary to take timely measures to prevent and control silkworm farmers at ordinary times or when stiff disease occurs, otherwise it will cause serious losses to silkworm farmers. The currently used anti-stiffness pesticides include bleaching powder anti-stiffness powder, formaldehyde anti-stiffness powder, gram chlorine, carbendazim, etc. However, these substances are harmful to humans and animals and have the risk of polluting the environment while pr...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P31/10A01N65/44A01N25/30A01P3/00
CPCA61K36/899A61P31/10A01N65/00A01N65/44A01N25/30A61K2236/333A61K2236/39A61K2236/55A61K2236/51
Inventor 刘冠卉姚彤郭锡杰屠洁
Owner JIANGSU UNIV OF SCI & TECH
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