Veterinary radix scutellariae powder injection and preparation method thereof

A technology of Scutellaria baicalensis and powder injection, which is applied in the directions of medical preparations without active ingredients, medical preparations containing active ingredients, and powder delivery, etc., to achieve the effect of lasting curative effect and improving the purification rate.

Inactive Publication Date: 2021-03-19
JIANGXI ZHONGCHENG MEDICINE GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, except for a veterinary Scutellaria baicalensis powder injection published by our company's patent number CN201310354976, there is no other manufacturer or research and development institution that has applied Scutellaria baicalensis powder injection to veterinary medicine. The application of Scutellaria baicalensis powder injection to veterinary medicine is the first of our company.

Method used

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  • Veterinary radix scutellariae powder injection and preparation method thereof
  • Veterinary radix scutellariae powder injection and preparation method thereof
  • Veterinary radix scutellariae powder injection and preparation method thereof

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Effect test

Embodiment 1

[0028] A veterinary Scutellaria baicalensis powder injection and a preparation method thereof, which consist of the following important raw materials:

[0029] 10000 parts of Scutellaria baicalensis, 100 parts of controlled release agent, the controlled release agent is a mixture of sodium citrate, dextran, and hydroxypropyl cellulose in a mass ratio of 1:4:6

[0030] The preparation process is as follows:

[0031] (1) Take Scutellaria baicalensis, ultrafinely pulverize it to 50-100um, add water to decoct for more than three times, combine the decoction liquid, stir and mix thoroughly, and concentrate the decoction liquid with a double-effect concentration tank until the density of the concentrated liquid is 1.5g / mL;

[0032] (2) Use hydrochloric acid to adjust the pH value of the concentrated solution to below 3.0, raise the temperature to 70°C, keep it warm for more than 10 minutes, and then let it stand still.

[0033] (3) Stir and dissolve the precipitate A with pure wate...

Embodiment 2

[0046] A veterinary Scutellaria baicalensis powder injection and a preparation method thereof, which consist of the following important raw materials:

[0047] 10,000 parts of Scutellaria baicalensis, 50 parts of controlled release agent, the controlled release agent is a mixture of sodium citrate, dextran, and hydroxypropyl cellulose in a mass ratio of 1:2:4

[0048] The preparation process is as follows:

[0049] (1) Take Scutellaria baicalensis, ultrafinely pulverize it to 50-100um, add water to decoct for more than three times, combine the decoction liquid, stir and mix thoroughly, and concentrate the decoction liquid with a double-effect concentration tank until the density of the concentrated liquid is 1g / mL;

[0050] (2) Use hydrochloric acid to adjust the pH value of the concentrated solution to below 3.0, raise the temperature to 60°C, keep it warm for more than 10 minutes, and then let it stand still.

[0051] (3) Stir and dissolve the precipitate A with pure water,...

Embodiment 3

[0064] A veterinary Scutellaria baicalensis powder injection and a preparation method thereof, which consist of the following important raw materials:

[0065] 10000 parts of Scutellaria baicalensis, 150 parts of controlled release agent, the controlled release agent is a mixture of sodium citrate, dextran, and hydroxypropyl cellulose in a mass ratio of 1:6:8

[0066] The preparation process is as follows:

[0067] (1) Take Scutellaria baicalensis, ultrafinely pulverize it to 50-100um, add water to decoct for more than three times, combine the decoction liquid, stir and mix thoroughly, and concentrate the decoction liquid with a double-effect concentration tank until the density of the concentrated liquid is 2g / mL;

[0068] (2) Use hydrochloric acid to adjust the pH value of the concentrated solution to below 3.0, raise the temperature to 80°C, keep it warm for more than 10 minutes, and then let it stand still.

[0069] (3) Stir and dissolve the precipitate A with pure water,...

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Abstract

The invention provides a veterinary radix scutellariae powder injection and a preparation method thereof. after a controlled release agent and auxiliary material medicine are added and injected into an animal body, the medicine absorption speed can be effectively controlled, the medicine use frequency is reduced while the medicine effect is improved, and the influence of the stress reaction of theanimal on the medicine effect is reduced. In the processes of filtration purification and filtration sterilization, an ultrafiltration membrane of the invention is used, and the filter membrane is prepared from a ceramic support body and an organic filter membrane which are prepared by a unique formula and a specific process, so that the filtration effect is good, the bacteria removal capabilityis high; and the purity of baicalin is effectively improved to 80%-85% and is remarkably improved in comparison with the purity of 75% of the national standard; and meanwhile, bacterial endotoxin is controlled to be about 0.014 EU / mL, so that heat source reaction and veterinary stress reaction are correspondingly reduced, and the healing effect is good.

Description

technical field [0001] The invention relates to the field of medicine processing, in particular to a veterinary skullcap powder injection and a preparation method thereof. Background technique [0002] Scutellaria baicalensis and its active ingredients exhibit inhibitory effects on a variety of viruses. In terms of improving the immunity of the body, Scutellaria baicalensis has a good regulatory function, which not only enhances the immune function, but also has a two-way regulating effect. Through plaque formation: experiments found that baicalin exhibited anti-SARS coronavirus activity. By measuring the T lymphocyte subsets after myocardial infarction, it was found that baicalin can alleviate the immune dysfunction of rats after myocardial infarction. [0003] According to the theory of traditional Chinese veterinary medicine, chicken infectious bronchitis belongs to the category of febrile disease. Because the lung governs qi and governs breathing, governs descending a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K9/14A61K47/12A61K47/36A61K47/38A61P31/14
CPCA61K9/0019A61K9/145A61K9/146A61K36/539A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P31/14
Inventor 付宁晨陈雪军洪志华付宁红支志鹏付宁鹏
Owner JIANGXI ZHONGCHENG MEDICINE GROUP
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