Material heat exchange system and method for fermentation reaction

A technology of heat exchange system and fermented material, which is applied in the field of material heat exchange system, can solve the problems of small space, high operating cost of circulating water, and difficult maintenance of heat exchange structure, etc.

Inactive Publication Date: 2021-04-06
ANHUI BBCA BIOCHEMICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there may be a large amount of thermal expansion and contraction in this structure, so as to prevent the connection tube from being easily broken under long-term work
[0005] Based on the solutions of the existing technology, the jacketed, spring tube, shell and tube, and heat exchanger heat exchange structures currently used in fermentation reactors have at least the following defects: First, they all need to be welded and installed inside the fermentation reactor , which reduces the effective use of space in the fermentation reactor. At the same time, the heat exchange structure of spring tube, shell and tube, and heat exchanger needs to be prefabricated inside the fermentation reactor in advance. The pipe processing cost is high and the material loss is large, which greatly increases the fermentation reactor. Production cost and production cycle; second, jacket type, spring tube type, shell and tube type, heat exchanger type heat exchange structure in the fermentation reactor sterilization process, the residual cold/heat medium in the heat exchange str

Method used

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  • Material heat exchange system and method for fermentation reaction
  • Material heat exchange system and method for fermentation reaction
  • Material heat exchange system and method for fermentation reaction

Examples

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Effect test

Embodiment 1

[0144] Example 1: Heat Exchange System

[0145] The present embodiment provides a heat exchange system for fermentation reaction, which specifically includes:

[0146] A total of 40 meters of latex tubes of DN15 are connected from the bottom of the fermentation reactor, of which 30 meters are formed into a circle with a diameter of 25cm and hovered in a 40L stainless steel container. The stainless steel container is filled with running tap water to keep the temperature low. Place spring water stop clips on the latex tube. The latex tubing was fed into a stainless steel container by a peristaltic pump at the 1 m position. After the latex tube came out of the stainless steel container, it was connected to the fermentation reactor through the feed port at the top of the fermentation reactor.

Embodiment 2

[0147] Example 2: Heat Exchange System

[0148] The present embodiment provides a heat exchange system for fermentation reaction, which specifically includes:

[0149] This embodiment provides a heat exchange system for fermentation reaction. A total of 40 meters of stainless steel hoses of DN15 are connected from the bottom of the fermentation reactor, of which 30 meters are formed into a circle with a diameter of 25cm and are coiled in a stainless steel container of a 100L chiller. . The stainless steel container is filled with ice water to keep the temperature low. Stainless steel hoses use sanitary ball valves to control material flow. The stainless steel hose pipeline enters the stainless steel container through a sanitary centrifugal pump at a position of 1 meter. After the stainless steel pipe comes out of the stainless steel container, it is connected to the fermentation reactor through the feed port on the upper part of the fermentation reactor.

Embodiment 3

[0150] Example 3: Heat Exchange System

[0151] This embodiment provides a heat exchange system for fermentation reaction, which specifically includes a fermentation material outflow pipe 6, a fermentation material heat exchange pipe, and a fermentation material inflow pipe 5 connected in sequence; the heat exchange pipe passes through a plate heat exchanger 4. Fully exchange heat between the fermentation material in the pipeline and the cold and hot medium / substance introduced into the plate heat exchanger 4 (the cold and hot medium is input through the cold and hot medium source pipe 2, and is output through the cold and hot medium return pipe 7) to achieve Heat exchange of fermentation material (e.g. figure 1 shown); the inlet of the fermented material outflow pipeline 6 is connected with the discharge port at the bottom of the fermentation reactor 8, and the bottom of the fermentation reactor is also provided with a filter device and a blowdown valve 10 (such as figure 2...

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PUM

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Abstract

The invention relates to a material heat exchange system for fermentation reaction. The material heat exchange system comprises a fermentation material outflow pipeline, a fermentation material heat exchange pipeline and a fermentation material inflow pipeline which are connected in sequence; an inlet of the fermentation material outflow pipeline is connected with a discharge port in the bottom of the fermentation reactor, an outlet of the fermentation material inflow pipeline is connected with a feed port in the top of the fermentation reactor, and no heat exchange structure exists in the fermentation reactor. The heat exchange system provided by the invention is simple in structure, the used pipelines and equipment are arranged outside the fermentation reactor, the internal space of the fermentation reactor is not occupied, the manufacturing period and the manufacturing cost of the fermentation reactor are greatly reduced, the transformation and maintenance are simple and convenient, the working safety is high, and the system provided by the invention can reduce the bacterial contamination risk in the fermentation reaction. The auxiliary period time of fermentation culture is shortened, the utilization rate of a fermentation reactor is increased, the heat exchange efficiency is improved, and high application and popularization value is achieved.

Description

technical field [0001] The invention relates to the field of fermentation technology, in particular to a material heat exchange system for fermentation reaction and a fermentation method using the system. Background technique [0002] The basic level of microbial fermentation production depends on the performance of the production strains, but with excellent strains, it is necessary to have the best environmental conditions, that is, the fermentation process, to optimize and improve its production capacity. Therefore, it is necessary to study the optimal fermentation process conditions for the production of strains, such as nutritional requirements, culture temperature, oxygen demand, etc., and design a reasonable fermentation process accordingly, so that the production strains are in the best growth conditions and achieve high-quality and high-yield effects. . The effect of temperature on fermentation and its regulatory control is one of the most important factors affectin...

Claims

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Application Information

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IPC IPC(8): C12M1/38C12M1/34C12M1/12C12M1/02C12M1/00C12P7/48C12P7/46C12P13/08C12P13/06C12P19/26C12P17/04C12P7/56C12R1/685C12R1/645C12R1/19
CPCC12M23/20C12M29/18C12M29/26C12M37/00C12M37/04C12M41/18C12M41/12C12P7/48C12P7/46C12P13/08C12P13/06C12P19/26C12P17/04C12P7/56Y02P20/10
Inventor 李荣杰穆晓玲王舒李维理孟瑶
Owner ANHUI BBCA BIOCHEMICAL CO LTD
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