Material heat exchange system and method for fermentation reaction

Abstract

The invention relates to a material heat exchange system for fermentation reaction. The material heat exchange system comprises a fermentation material outflow pipeline, a fermentation material heat exchange pipeline and a fermentation material inflow pipeline which are connected in sequence; an inlet of the fermentation material outflow pipeline is connected with a discharge port in the bottom of the fermentation reactor, an outlet of the fermentation material inflow pipeline is connected with a feed port in the top of the fermentation reactor, and no heat exchange structure exists in the fermentation reactor. The heat exchange system provided by the invention is simple in structure, the used pipelines and equipment are arranged outside the fermentation reactor, the internal space of the fermentation reactor is not occupied, the manufacturing period and the manufacturing cost of the fermentation reactor are greatly reduced, the transformation and maintenance are simple and convenient, the working safety is high, and the system provided by the invention can reduce the bacterial contamination risk in the fermentation reaction. The auxiliary period time of fermentation culture is shortened, the utilization rate of a fermentation reactor is increased, the heat exchange efficiency is improved, and high application and popularization value is achieved.

Description

technical field [0001] The invention relates to the field of fermentation technology, in particular to a material heat exchange system for fermentation reaction and a fermentation method using the system. Background technique [0002] The basic level of microbial fermentation production depends on the performance of the production strains, but with excellent strains, it is necessary to have the best environmental conditions, that is, the fermentation process, to optimize and improve its production capacity. Therefore, it is necessary to study the optimal fermentation process conditions for the production of strains, such as nutritional requirements, culture temperature, oxygen demand, etc., and design a reasonable fermentation process accordingly, so that the production strains are in the best growth conditions and achieve high-quality and high-yield effects. . The effect of temperature on fermentation and its regulatory control is one of the most important factors affectin...

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Problems solved by technology

However, there may be a large amount of thermal expansion and contraction in this structure, so as to prevent the connection tube from being easily broken under long-term work

[0005] Based on the solutions of the existing technology, the jacketed, spring tube, shell and tube, and heat exchanger heat exchange structures currently used in fermentation reactors have at least the following defects: First, they all need to be welded and installed inside the fermentation reactor , which reduces the effective use of space in the fermentation reactor. At the same time, the heat exchange structure of spring tube, shell and tube, and heat exchanger needs to be prefabricated inside the fermentation reactor in advance. The pipe processing cost is high and the material loss is large, which greatly increases the fermentation reactor. Production cost and production cycle; second, jacket type, spring tube type, shell and tube type, heat exchanger type heat exchange structure in the fermentation reactor sterilization process, the residual cold / heat medium in the heat exchange structure encounters steam Post-expansion oscillations can easily lead to tearing of welds. During the fermentation process, the leakage of cold / hot medium in the heat exchange structure is likely to cause bacterial contamination during the fermentation process. Moreover, the internal heat exchange structure of the existing fermentation reactor is complex, with many pipes, and it is difficult to clean. , once the cleaning is not thorough and leaves dead corners, it will increase the risk of bacterial contamination; third, in order to ensure that the heat exchange structure does not leak, it is necessary to check for leaks at the welds, and increase the auxiliary cycle time of fermentation culture; fourth, the existing fermentation reaction It is difficult to maintain the internal heat exchange structure of the fermentation reactor, the internal structure of the fermentation reactor is complex, and the space is small; fifth, the existing heat exchange structure has low heat exchange efficiency, heat loss and high operating costs for multiple circulating water, etc.

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