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Compound dragon's blood oral ulcer medicine composition and preparation method thereof

A technology for oral ulcers and dried dragon's blood is applied in the preparation of a compound dragon's blood oral ulcer pharmaceutical composition and the field of preparation thereof, which can solve the problems of powder use, inconvenience in carrying, limited rational application, low patient acceptance, and the like, and achieves Pain relief, healing promotion, prevention of saliva loss

Pending Publication Date: 2021-06-25
昆明市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Coptis chinensis in the prescription tastes extremely bitter, which makes the patient's acceptance low. The medicine in the prescription is not easy to stick to the ulcer site, and the dosage is difficult to control, which greatly limits the rational application of the prescription.
[0004] In order to overcome the difficulties of using and carrying inconvenience of traditional powders and ensure the efficacy of the medicine, it is necessary to improve the existing technology

Method used

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  • Compound dragon's blood oral ulcer medicine composition and preparation method thereof
  • Compound dragon's blood oral ulcer medicine composition and preparation method thereof
  • Compound dragon's blood oral ulcer medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] The compound of the examples of the present embodiment includes a component of the following weight: 5.5g of dragon blood, 21.5 g of a yellow medicine (about 2.75g), 1.4G, chitosan, chitosan 4g, gelatin 2.5g, aloe polysaccharide 1g, ethylcellulose 5g.

[0042] The pharmaceutical composition of the present embodiment is a double-layer film structure, including a blank spacer layer, and a pharmaceutical film layer is formed on a blank spacer film film, and the pharmaceutical membrane layer film film comprises a mixed uniform blank matrix and a compound solution.

[0043] According to the Chinese medicine compound of the treatment of oral ulcers, first take the ethylcellulose to add ethanol solution, put it on the glass plate naturally drying to make blank isolation layers, backup; re-use, yellow, mixed, concentrate, dry , Made a dry paste, mixed with dragon, bicycles, smash, sieving, preparing compound dragon blood exhaustion powder, compound potion add anhydrous ethanol to p...

Embodiment 2

[0054] The compound dragon blood of the present embodiment includes a component comprising the following weight: 1.4.9G (extract of about 5.5g), fridge 2.9g, chitosan 8g, gelatin 5.1 g, aloe polysaccharide 2g, ethylcellulose 10g.

[0055] The pharmaceutical composition of the present embodiment is a double-layer film structure, including a blank spacer layer, and a pharmaceutical film layer is formed on a blank spacer film film, and the pharmaceutical membrane layer film film comprises a mixed uniform blank matrix and a compound solution.

[0056] According to the Chinese medicine compound of the treatment of oral ulcers, first take the ethylcellulose to add ethanol solution, put it on the glass plate naturally drying to make blank isolation layers, backup; re-use, yellow, mixed, concentrate, dry , Made a dry paste, mixed with dragon, bicycles, smash, sieving, preparing compound dragon blood exhaustion powder, compound potion add anhydrous ethanol to prepare a compound solution, a...

Embodiment 3

[0067] The compound dragon blood oral ulcer drug composition includes a component of the following weight: 5.49g of the dragon blood, 29.3g of the yellow medicine (about 3.75g of extract), 1.37 g of ice, chitosan 6g, gelatin 3.75g, aloe vera polysaccharide 1.7g, ethyl cellulose 7.5 g.

[0068] The pharmaceutical composition of the present embodiment is a double-layer film structure, including a blank spacer layer, and a pharmaceutical film layer is formed on a blank spacer film film, and the pharmaceutical membrane layer film film comprises a mixed uniform blank matrix and a compound solution.

[0069] According to the Chinese medicine compound of the treatment of oral ulcers, first take the ethylcellulose to add ethanol solution, put it on the glass plate naturally drying to make blank isolation layers, backup; re-use, yellow, mixed, concentrate, dry , Made a dry paste, mixed with dragon, bicycles, smash, sieving, preparing compound dragon blood exhaustion powder, compound potion...

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Abstract

The invention relates to a compound dragon's blood oral ulcer medicine composition and a preparation method thereof. The composition comprises the following components in parts by weight: 4-10 parts of dragon's blood, 15-20 parts of coptis chinensis, 2-4 parts of borneol, 10-15 parts of chitosan, 5-10 parts of gelatin, 5-10 parts of aloe polysaccharide and 10-15 parts of ethyl cellulose. The blank isolation layer can effectively isolate the bitter taste of coptis chinensis in the medicine film, the acceptance of a patient is improved, the medicine can be prevented from being washed away by saliva, the availability of the medicine is improved, and it is guaranteed that the medicine is released at a fixed point at the dental ulcer part. The traditional Chinese medicine is convenient to store, carry and use, has the effects of resisting bacteria, diminishing inflammation, easing pain and healing wound, and can effectively promote ulcer healing and relieve pain of patients.

Description

Technical field [0001] The present invention belongs to the technical field of treatment of recurrent oral ulcers, in particular to prepare a compound of the pharmaceutical composition and preparation method thereof. Background technique [0002] Recurrent APHTHOUS ULCER, RAU, is also known as recurrence, Affil, is a common disease. At present, recurrent oral ulcers are still unclear. The study found that there were 10% to 25% of the disease, and the prevalence of a particular population was as high as 50%. The pathogenesis of the RAU is mostly oral mucosa, lips, cheek and tongue side mucosa. This disease has the characteristics of recurrence, periodic, self-healing, greatly affects the patient's work and life. Studies have shown that the pathogenesis of recurrent oral ulcers and mental psychological factors, food factors, immunity factors, genetic factors, oral hygiene factors, bacterial factors, etc. The treatment methods mainly have Chinese medicine treatment, Western medicine...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/70A61K47/38A61P1/02A61K31/045
CPCA61K36/896A61K36/718A61K31/045A61K9/7007A61K47/38A61K9/006A61P1/02A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 张韶湘余晓玲陈凌云张荣平彭霜邹昱蕾张昆欣刘旭戚琬若顾蘅
Owner 昆明市中医医院
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