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Resin Mongolian medicine powder formula granules and preparation method thereof

A technology of formula granules and resins, which is used in pharmaceutical formulas, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., can solve problems such as deterioration, difficulty in taking Mongolian medicine, and easy pollution, and achieve simple composition. , Solve the effect of easy pollution and deterioration, good stability

Active Publication Date: 2021-07-02
那生桑 +2
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The invention prepares the resin Mongolian medicine into formula granules, realizes the improvement of the Mongolian medicine form, and solves the problems of difficult taking, easy pollution and deterioration of the Mongolian medicine; the formula granule components of the present invention only include resinous Mongolian medicine and talcum powder, and talc The amount of powder used is small, and there will be no problems that the excipients exceed the standard and affect the efficacy of the drug

Method used

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  • Resin Mongolian medicine powder formula granules and preparation method thereof
  • Resin Mongolian medicine powder formula granules and preparation method thereof
  • Resin Mongolian medicine powder formula granules and preparation method thereof

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preparation example Construction

[0031] The present invention also provides the preparation method of the resinous Mongolian medicine powder formula particles described in the above scheme, comprising the following steps:

[0032] The resinous Mongolian medicine is pulverized at low temperature and then sieved to obtain the original resinous Mongolian medicine powder;

[0033] The resinous Mongolian medicine raw powder, talc powder and ethanol are mixed to carry out wet granulation, and the obtained wet granules are dried to obtain the resinous Mongolian medicine powder formula particles.

[0034] In the present invention, the resinous Mongolian medicine is pulverized at low temperature and then sieved to obtain the original powder of the resinous Mongolian medicine. In the present invention, the temperature of the low-temperature pulverization is -20 to -40°C, more preferably -20°C; the resin-based Mongolian medicine has certain astringency and viscosity, and the present invention adopts the low-temperature ...

Embodiment 1

[0043] Preparation of black cloud incense powder formula particles: raw materials are black cloud incense, talc and 10% ethanol solution (hereinafter referred to as 10% ethanol solution), and the consumption ratio of the raw materials is shown in Table 1.

[0044] The preparation method is as follows: weighing the black cloud incense, and then pulverizing it at a low temperature of -20 ° C, sieving the pulverized material with an electromagnetic vibrating screen to obtain a 100-mesh black cloud incense original powder; mixing the black cloud incense original powder and talc powder. 30min, then add 10% ethanol solution for mixing to obtain soft material; extrude the soft material through a 14-mesh sieve, dry the obtained wet granules at 40°C to a water content of less than 8%, and then use a 18-mesh sieve to sieve granules to obtain Heiyunxiang formula granules; use the inner packaging material to divide the Heiyunxiang powder formula granules, and then pack the outer packaging,...

Embodiment 2

[0058] In this experiment, the influence of the temperature of low-temperature pulverization on the pulverization effect was tested: take three parts of the same mass (200g) of black cloud, and pulverize them at different low temperatures. The pulverization time is 20min, and the powder is taken out for particle size distribution analysis. .

[0059] Table 3 Effects of different low temperature conditions on crushing efficiency

[0060]

[0061] Resin-based Mongolian medicines have certain astringency and viscosity. The invention adopts the method of low-temperature pulverization to increase its brittleness and improve the pulverization efficiency. According to the data in Table 3, it can be seen that the temperature of low-temperature pulverization has a significant impact on the pulverization effect. When the pulverization temperature is -5°C, the 100-mesh powder in the obtained powder is only 5%, while the pulverization temperature is -20°C. And -40 ℃, the proportion of...

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Abstract

The invention relates to the technical field of Mongolian medicine preparations, and provides resin Mongolian medicine powder formula granules and a preparation method thereof. The resin Mongolian medicine powder formula granules comprise the following components: resin Mongolian medicine and talcum powder. The preparation method comprises the following steps: crushing the resin Mongolian medicine, mixing the crushed resin Mongolian medicine with the talcum powder, and carrying out wet granulation by taking an ethanol solution as a wetting agent to obtain the resin Mongolian medicine powder formula granules. The purpose of'no change of medicine material basis' in national medicine research and development is achieved, a modern pharmacy method is applied, single Mongolian medicine decoction pieces are directly smashed and processed into novel formula granules, the dosage form of the Mongolian medicine is improved, and the problems that the Mongolian medicine is difficult to take and prone to pollution and deterioration are solved; in addition, the traditional attributes and medication habits of the Mongolian medicine can be completely reserved, the quality controllability and stability of the resin Mongolian medicine are comprehensively improved, and the safety and the effectiveness of the resin Mongolian medicine are guaranteed.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a resinous Mongolian medicine powder formula particle and a preparation method thereof. Background technique [0002] Mongolian medicine is an important part of traditional medicine in the world and in China. It has distinctive Mongolian national cultural characteristics. It is a traditional medicine system with a long history, complete theory, reliable curative effect and unique color. It occupies an important position in my country's national medicine culture. It not only provides medical security for the prosperity of the Mongolian nation and human health, but also makes great contributions to social progress. Western medicine is helpless in the face of many modern diseases. In the process of seeking solutions, the concept of learning from nature has returned to the public's field of vision. It happens that the attributes of nature are the innate genes of Mo...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K36/896A61K9/16A61K47/02A61K47/10
CPCA61K36/23A61K36/185A61K36/48A61K36/15A61K36/328A61K36/889A61K36/896A61K36/30A61K36/22A61K9/1611A61K9/1617A61K2300/00
Inventor 王玉华
Owner 那生桑
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