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A kind of resin Mongolian medicine powder formula granule and preparation method thereof

A technology of formula granules and resins, which is applied in pharmaceutical formulas, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., can solve the problems of easy pollution, difficulty in taking Mongolian medicine, deterioration, etc., and achieve good stability. , Solve the effect of easy pollution and deterioration, and simple composition

Active Publication Date: 2022-05-13
那生桑 +2
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The invention prepares the resin Mongolian medicine into formula granules, realizes the improvement of the Mongolian medicine form, and solves the problems of difficult taking, easy pollution and deterioration of the Mongolian medicine; the formula granule components of the present invention only include resinous Mongolian medicine and talcum powder, and talc The amount of powder used is small, and there will be no problems that the excipients exceed the standard and affect the efficacy of the drug

Method used

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  • A kind of resin Mongolian medicine powder formula granule and preparation method thereof
  • A kind of resin Mongolian medicine powder formula granule and preparation method thereof
  • A kind of resin Mongolian medicine powder formula granule and preparation method thereof

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preparation example Construction

[0031] The present invention also provides a method for preparing resin-based Mongolian medicine powder formula granules described in the above scheme, comprising the following steps:

[0032] The resinous Mongolian medicine is pulverized at low temperature and sieved to obtain the resinous Mongolian medicine raw powder;

[0033] The resin-based Mongolian medicine powder, talcum powder and ethanol are mixed for wet granulation, and the obtained wet granules are dried to obtain the resin-type Mongolian medicine powder formula granules.

[0034] In the invention, the resinous Mongolian medicine is pulverized at low temperature and then sieved to obtain the original powder of the resinous Mongolian medicine. In the present invention, the temperature of the low-temperature pulverization is -20 to -40°C, more preferably -20°C; the resinous Mongolian medicine has a certain astringency and viscosity, and the present invention uses low-temperature pulverization to increase the resinou...

Embodiment 1

[0043] Preparation of Heiyunxiang powder formula granules: raw materials are Heiweixiang powder, talcum powder and 10% ethanol solution (subsequently referred to as 10% ethanol solution), the dosage ratio of raw materials is shown in Table 1.

[0044] The preparation method is as follows: weigh the black kelp and crush it at a low temperature of -20°C, and sieve the crushed material with an electromagnetic vibrating sieve to obtain 100-mesh black kelp powder; mix the black kelp powder with talc powder 30min, then add 10% ethanol solution for mixing to obtain soft material; extrude the soft material through a 14-mesh sieve, dry the obtained wet granules at 40°C until the water content is less than 8%, and then use a 18-mesh sieve to sieve granules to obtain Heiyunxiang formula granules; the Heiyunxiang powder formula granules are subpackaged with inner packaging materials, then wrapped in outer packaging, and put into storage after passing the inspection. For the preparation pr...

Embodiment 2

[0058] This experiment tests the effect of the temperature of low-temperature grinding on the grinding effect: Take three parts of Heiyunxiang with the same mass (200g) and grind them at different low temperatures. The grinding time is 20 minutes, and the powder is taken out for particle size distribution analysis. The results are shown in the table below .

[0059] Table 3 Effect of different low temperature conditions on crushing efficiency

[0060]

[0061] Resin Mongolian medicines have a certain degree of astringency and viscosity. The present invention adopts the method of low-temperature crushing to increase its brittleness and improve crushing efficiency. The particle size of the granulated powder of the formula granules is 100 mesh is the best. According to the data in Table 3, it can be seen that the temperature of low-temperature pulverization has a significant impact on the pulverization effect. When the pulverization temperature is -5°C, the 100 mesh powder in ...

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Abstract

The invention relates to the technical field of Mongolian medicine preparations, and provides resinous Mongolian medicine powder formula granules and a preparation method thereof. The components of the formula granules of resinous Mongolian medicine powder provided by the invention include resinous Mongolian medicine and talcum powder. In the preparation method provided by the invention, the resinous Mongolian medicine is pulverized and mixed with talcum powder, and the ethanol solution is used as a wetting agent to carry out wet granulation to obtain the resinous Mongolian medicine powder formula granules. The present invention aims at "unchanging the substance basis of the drug" in the national drug research and development, and applies the method of modern pharmacy to directly crush the single-flavored pieces of Mongolian medicine and process them into new formula granules, which realizes the improvement of the Mongolian drug form and solves the problem of taking Mongolian medicine. Difficult, easy to pollute and deterioration problems, and the invention can completely retain the traditional properties and medication habits of Mongolian medicine, comprehensively improve the quality controllability and stability of resinous Mongolian medicine, and ensure the safety and effectiveness of resinous Mongolian medicine.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a resin-based Mongolian medicine powder formula granule and a preparation method thereof. Background technique [0002] Mongolian medicine is an important part of the world and Chinese traditional medicine. It has distinctive Mongolian national cultural characteristics. It is a traditional medical system with a long history, complete theory, reliable curative effect and unique color. It occupies an important position in my country's national medical culture. It not only provides medical security for the multiplication of the Mongolian nation and human health, but also makes great contributions to social progress. Western medicine is helpless in the face of many modern diseases. In the process of seeking solutions, the concept of learning from nature has returned to the public eye. It happens that the nature of nature is the innate gene of Mongolian medicine. T...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61K36/896A61K9/16A61K47/02A61K47/10
CPCA61K36/23A61K36/185A61K36/48A61K36/15A61K36/328A61K36/889A61K36/896A61K36/30A61K36/22A61K9/1611A61K9/1617A61K2300/00
Inventor 王玉华
Owner 那生桑
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