Preparation method of three-dimensional diabetic foot ulcer functional medical dressing

Abstract

The invention discloses a preparation method of a three-dimensional diabetic foot ulcer functional medical dressing. The preparation method comprises the following steps: S1, taking a core layer solution, a middle layer solution and a shell layer solution; conducting printing through the microfluidic 3D printing assembly, so as to introduce the core layer solution into the inner phase channel, introduce the middle layer solution into the middle phase channel, and introduce the shell layer solution into the outer phase channel; and S2, controlling the flow velocity in each channel, setting parameters of a 3D printer, making the flow velocity of the inner phase channel 0-110 mL / h, the flow velocity of the intermediate phase channel 150-270 mL / h, and the flow velocity of the outer phase channel 30-110 mL / h, and utilizing the 3D printer for controlling the micro-fluidic chip to print the three-dimensional diabetic foot ulcer functional medical dressing. According to the scheme of the invention, by controlling the speed, the three-dimensional structure assembled by the microfibers with multiple layers of shell / core structures can be obtained, the size can be regulated and controlled, the swelling rate, the water absorption rate and the like are good, and the medical dressing has good application prospects in diabetic foot ulcer medical supplies.

Description

technical field [0001] The invention belongs to the field of medical devices, and in particular relates to a preparation method of a three-dimensional diabetic foot ulcer functional medical dressing. Background technique [0002] Diabetes is a chronic metabolic disease worldwide, accompanied by premature death, high morbidity and medical costs. Research data shows that many diabetic patients will suffer from foot wound infection in their lifetime and cause non-healing chronic ulcers. Among them, some diabetic foot ulcer (DFU) patients need amputation because they cannot heal, which is the primary cause of non-traumatic amputation and seriously affects Human physical and mental health and quality of life. In recent years, in order to achieve DFU wound healing, clinical treatment methods include debridement, prevention of bacterial infection, negative pressure drainage, hyperbaric oxygen therapy, physical therapy, blood transfusion therapy-platelet-rich plasma, tissue transpl...

AI Technical Summary

Problems solved by technology

However, the preparation process of three-dimensional medical dressings in the prior art is relatively complicated, requiring a lot of post-processing, and the production efficiency is low

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