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Application of cynanchum thesioides in preparation of medicine for supplementing calcium and preventing osteoporosis

A technology for osteoporosis and sweet potato, applied in the fields of phytochemistry and biopharmaceuticals, can solve the problems of not yet discovered sweet potato, and less research on practical products, and achieves the promotion of calcium absorption, prevention of osteoporosis, and promotion of bone The effect of the transfer

Active Publication Date: 2021-08-27
宁夏奶瓜瓜生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, the research on ground shoot melon mainly focuses on chemical components, tissue culture and artificial domestication, content determination and quality standards, and there are few researches on practical products.
So far, it has not been found in the art that ground shoot melon is effective in calcium supplementation and anti-osteoporosis

Method used

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  • Application of cynanchum thesioides in preparation of medicine for supplementing calcium and preventing osteoporosis
  • Application of cynanchum thesioides in preparation of medicine for supplementing calcium and preventing osteoporosis
  • Application of cynanchum thesioides in preparation of medicine for supplementing calcium and preventing osteoporosis

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 Radix Melon Whole Herb Powder, Preparation of Radix Melon Fruit Powder

[0028] The whole herb of Radix Gherkin is taken by weighing 500g, cut into sections of 0.5 cm, pulverized with a traditional Chinese medicine grinder, and passed through an 80-mesh Chinese medicine sieve to obtain the whole herb powder of Radix Gherkin. 500 g of the sun-dried fruit of the ground shoot melon is cut in half, crushed with a traditional Chinese medicine grinder, and passed through an 80-mesh Chinese medicine sieve to obtain the ground shoot melon fruit powder.

Embodiment 2

[0029] Embodiment 2 Radix Melon Whole Herb Extract, Preparation of Radix Melon Fruit Extract

[0030] Take the whole herb of ground shoot melon, cut it into 0.5cm sections, weigh 300g, put it into a 5L round bottom flask, add 3000mL of distilled water to soak for 30 minutes, and use an electric heating mantle to heat and reflux for 1h (extraction temperature is 100°C, filter with 8 layers of gauze) , repeat three times to combine the filtrate, pour the filtrate into 250mL evaporating dish in portions, put it on a water bath to evaporate and dry (the temperature of the water bath is 90 degrees Celsius), when the filtrate in the evaporating dish is dry quickly, pour the filtrate again until all the filtrate evaporates Dry. Dry until pressed and become brittle, weigh 100.8g of extract. According to this method, the yield is 33% to 34%. It is necessary to repeatedly prepare about 1kg of extract for later use.

[0031] Take 250g of dried ground shoot melon, cut it in half, put it i...

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Abstract

The invention discloses application of cynanchum thesioides in preparation of a medicine for supplementing calcium and preventing osteoporosis. The cynanchum thesioides medicinal material powder and the cynanchum thesioides medicinal material extract can improve the serum calcium concentration of rats and the content of 1, 25-dihydroxy vitamin D3 (DHVD3) and calcitonin (CT), and reduce the content of alkaline phosphatase and parathyroid hormone (PTH) of the rats, and through the indexes, what can be indicated is that cynanchum thesioides promotes calcium absorption by supplementing serum calcium and promotes calcium in serum to be transferred to sclerotin, and osteoporosis is prevented.

Description

technical field [0001] The invention relates to the technical fields of phytochemistry and biopharmaceuticals, and more specifically relates to the application of sweet potato in the preparation of medicines for calcium supplementation and osteoporosis prevention. Background technique [0002] At present, people mainly use calcium carbonate as a calcium supplement, but long-term use of calcium carbonate is prone to belching and constipation, and occasionally choline syndrome, manifested as hypercalcemia, alkalosis and renal insufficiency, excessive long-term use can cause Gastric acid secretion rebound increased, and hypercalcemia can occur. Moreover, osteoporosis and calcium deficiency are common diseases of the elderly, and the gastrointestinal function of the elderly is weakened, and side effects are more likely to occur after taking calcium carbonate. Finding new calcium supplements has become a top priority. [0003] Ground shoot melon is a perennial herbaceous plant o...

Claims

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Application Information

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IPC IPC(8): A61K36/27A61P3/14A61P19/10A61P5/20A61P5/18A61K131/00
CPCA61K36/27A61P3/14A61P19/10A61P5/20A61P5/18
Inventor 刘红梅
Owner 宁夏奶瓜瓜生物科技有限公司
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