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Stable vitamin C preparation and application method thereof

A technology of vitamins and preparations, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as poor stability of vitamin C, improve efficacy, reduce the risk of oxidation, and improve oxidation stability Effect

Pending Publication Date: 2021-10-08
谢志辉生物医药研究院(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a stable vitamin C preparation, which solves the technical problem of poor stability of vitamin C in vitamin C skin care products

Method used

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  • Stable vitamin C preparation and application method thereof
  • Stable vitamin C preparation and application method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A stable formulation of vitamin C comprising agent A, agent B and airtight containers (such as Figure 1-2 shown).

[0032] The container in this embodiment has an inner layer cavity and an outer layer cavity, and the inner layer cavity and the outer layer cavity have independent liquid guide tubes 8, and the two liquid guide tubes 8 communicate with the same nozzle 3, and the liquid guide tube 8 A liquid spraying structure is respectively arranged inside, and the liquid spraying structure of the container may be an existing press-type liquid spraying structure, which is not limited here. The container in this embodiment includes a main body 1, a pressing handle 2, and a nozzle 3, and the spraying structure is a pressing pump. The main body is cylindrical and includes an inner cavity and an outer cavity. The pressing pump includes a piston 5, a spring 6, and a steel ball 7. The piston 5 is connected to the pressing handle 2, the nozzle 3 is respectively connected to ...

Embodiment 2

[0037] The difference between this embodiment and Example 1 lies in the composition and content of Agent A and Agent B. Specifically, Agent A is composed of the following components in mass percentage: vitamin C 25%, betaine 8%, EDTA disodium 0.02 %, balance 1,2-propanediol. Agent B is an aqueous agent, consisting of the following components in mass percentage: 3% 1,2-pentanediol, 0.5% glycerol glucoside, 0.2% xanthan gum, 0.05% ethylhexylglycerin, 0.05% caprylyl glycol and Balance water. The addition of betaine and disodium EDTA further increases the overall specific gravity of agent A, which is more conducive to covering agent A with polydimethylsiloxane after the container is shaken and left standing. At the same time, betaine can prevent the crystallization of vitamin C, and disodium EDTA can complex metal ions such as iron to prevent the oxidation of vitamin C catalyzed by trace iron ions in the system.

[0038] In this example, the mixing ratio of agent A and agent B i...

Embodiment 3

[0040] The difference between this example and Example 1 lies in the composition and content of Agent A and Agent B. Specifically, Agent A consists of the following components in mass percentage: vitamin C 20%, betaine 2%, EDTA disodium 0.03 %, balance 1,3-propanediol. 1.5 g of liquid paraffin was also added to the inner layer of the container. Agent B is composed of the following components in mass percentage: 2% of 1,2-pentanediol, 0.5% of glycerol glucoside, 0.3% of xanthan gum, 0.1% of ethylhexylglycerin, 0.02% of caprylyl glycol and the balance of water.

[0041] In this example, the mixing ratio of agent A and agent B is 1:3.

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Abstract

The invention provides a stable vitamin C preparation. The preparation is composed of an agent A and an agent B that are independently arranged; the agent A comprises vitamin C and a non-aqueous solvent; the agent B is an aqueous solution; and the liquid level of the agent A is covered with an antioxidant additive. In the stable vitamin C preparation, the vitamin C is directly adopted to replace a vitamin C derivative; the non-aqueous solvent is used for dissolving the vitamin C to reduce oxidation; and the antioxidant additive is used for isolating the vitamin C from being in contact with oxygen to further reduce oxidation risks. Therefore, the stability of the vitamin C is greatly improved, and the shelf storage time of the vitamin C is greatly prolonged. Compared with the derivative of the vitamin C, the preparation has a better effect and a low cost.

Description

technical field [0001] The invention belongs to the technical field of daily cosmetics, and in particular relates to a stable vitamin C preparation and a method for using the stable vitamin C preparation. Background technique [0002] Vitamin C (also known as "ascorbic acid") is a nutrient in our human body. It has a wide range of application values ​​in the fields of beauty, medicine and health care. It is used externally on the surface of human skin to have whitening, oil control, anti-acne, repairing and other effects. However, , vitamin C also has the disadvantage of being easily oxidized and difficult to apply. Currently, it is used in cosmetic preparations for external use, usually derivatives of vitamin C, such as sodium ascorbyl phosphate, magnesium ascorbyl phosphate, 2-o-ethyl ascorbic acid, Ascorbyl glucoside, etc., but the use of these derivatives not only has a high cost (usually 5 to 20 times the price of ordinary vitamin C), but also has a large amount of loss...

Claims

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Application Information

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IPC IPC(8): A61K8/67A61K8/891A61K8/31A61K8/44A61K8/60A61K8/34A61Q19/02A61Q19/00
CPCA61K8/676A61K8/891A61K8/31A61K8/44A61K8/602A61K8/345A61Q19/02A61Q19/008A61K2800/52
Inventor 谢志辉
Owner 谢志辉生物医药研究院(广州)有限公司
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