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Whitening composition as well as preparation and whitening method thereof

A composition and a whitening technology, which are applied to the whitening composition and its preparation and whitening fields, can solve the problems of high injection frequency, damage to the digestive system, urinary system, poor stability, etc., and achieve the effect of promoting metabolic renewal

Pending Publication Date: 2021-10-19
杜德(江门)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tranexamic acid can only improve dark spots from thickening, expanding and increasing, so as to prevent and improve skin pigmentation, but the improvement effect of accumulated melanin is not obvious; vitamin C has anti-oxidation, promotes collagen synthesis and other effects, and at least It is necessary to take more than 1000mg of vitamin C, but long-term high-dose intake of vitamin C will promote the absorption of iron in the blood system, cause iron-rich red blood cell anemia, and reduce the intestinal response to vitamin B 12 Absorption of megaloblastic anemia can accelerate the deterioration of megaloblastic anemia. If the daily dosage exceeds 5 grams, it can lead to hemolysis, and severe cases can be fatal. Sudden withdrawal after long-term large doses may cause rebound scurvy, which is harmful to the digestive system and urinary system. System, etc. cause certain damage; the added natural herbal essence varies from person to person, and may not be suitable for all individuals
The above anti-oxidation principle can inhibit the diffusion of melanin for a short time, but with the gradual production of melanin, it will still return to the previous state, and the stability is not good
Moreover, most of the existing whitening preparation injection routes are intravenous injection, and the injection frequency is relatively high.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 Preparation of Compound Type I / II Personalized Facial Injection Whitening Preparation Set

[0035] In the present invention, type I preparation and type II preparation are combined to form a composite type I / II personalized facial injection whitening preparation set, and the steps are as follows:

[0036] 1. Type I preparation preparation:

[0037] Dissolve 60 U of hyaluronidase in 30 mL of injection-grade saline to prepare a 2 U / mL hyaluronidase solution, which is divided into 2.5 mL / bottle.

[0038] 2. Type II preparation preparation:

[0039] (1) Umbilical cord collection

[0040] 1) Donors come from hospitals with donor screening capabilities that have obtained the "Medical Institution Practice License".

[0041] 2) Donor selection

[0042] The general information, past medical history, family history, etc. of the donor are collected, and the donor is required to have no family genetic disease, no history of malignant tumor disease, no infectious disea...

Embodiment 2

[0072] Example 2 Preparation of Compound Type I / II Personalized Facial Injection Whitening Preparation Set

[0073] In the present invention, type I preparation and type II preparation are combined to form a composite type I / II personalized facial injection whitening preparation set, and the steps are as follows:

[0074] 1. Type I preparation preparation:

[0075] Dissolve 60 U of hyaluronidase in 30 mL of injection-grade saline to prepare a 2 U / mL hyaluronidase solution, which is divided into 2.5 mL / bottle.

[0076] 2. Type II preparation preparation:

[0077] Dissolve 1 g of tranexamic acid in 30 mL of injection-grade physiological saline to prepare a 0.03 g / mL tranexamic acid solution, which is divided into 2.5 mL / bottle.

[0078] 3. Whitening preparation set combination

[0079] The 2.5mL type I preparation and 2.5mL type II preparation prepared in step 1 and step 2 are combined to form a composite type I / II personalized facial injection whitening preparation set.

Embodiment 3

[0080] Example 3 Preparation of Composite Type I / II Personalized Facial Injection Whitening Preparation Set

[0081] In the present invention, type I preparation and type II preparation are combined to form a composite type I / II personalized facial injection whitening preparation set, and the steps are as follows:

[0082] 1. Type I preparation preparation:

[0083] Dissolve 60 U of hyaluronidase in 30 mL of injection-grade saline to prepare a 2 U / mL hyaluronidase solution, which is divided into 2.5 mL / bottle.

[0084] 2. Type II preparation preparation:

[0085]Dissolve 22.5g of vitamin C in 30mL of injection-grade physiological saline to prepare a 0.75g / mL vitamin C solution, and pack it into 2.5mL / bottle.

[0086] 3. Whitening preparation set combination

[0087] The 2.5mL type I preparation and 2.5mL type II preparation prepared in step 1 and step 2 are combined to form a composite type I / II personalized facial injection whitening preparation set.

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Abstract

The invention relates to the technical field of cosmetics, in particular to a whitening composition, a preparation thereof and a whitening method. The whitening composition is prepared from hyaluronidase and a whitening component. The hyaluronidase and stem cell exosome suspension or other whitening components are uniformly mixed for use, the hyaluronidase can promote the increase of cell permeability, and the stem cell exosome suspension or other whitening components can recover the activity of facial skin extracellular matrix collagen and elastin, activate an anti-oxidation system, promote the metabolic renewal of the skin, and realize the purposes of removing melanin and free radicals and whitening and refining the skin.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a whitening composition, its preparation and a whitening method. Background technique [0002] Melanin is a kind of biological pigment, which is formed by a series of chemical reactions of tyrosine or 3,4-dihydroxyphenylalanine. Animals, plants and protozoa all have this same pigment. Melanin usually exists in the form of aggregation. Melanin is actually an amino acid derivative, which is present in everyone's body. It is produced and stored in a special cell called melanocyte. It is because of the existence of melanin that the skin has its color. 20-25 years old is the active period for the formation of melanin precipitation. They exist in the middle of the cells in the basal layer of the skin, but a substance called "melanogenous substance", also known as "chromatocytes". Pigment mother cells secrete melanin pigment. When ultraviolet rays (B wave, A wave) irradiate the ski...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/44A61K8/64A61K8/66A61K8/67A61Q19/02C12N5/0775
CPCA61K8/99A61K8/66A61K8/44A61K8/676A61K8/64A61Q19/02C12N5/0668A61K2800/5922A61K2800/91C12N2509/10
Inventor 张玲洁周荣程黄婉仪
Owner 杜德(江门)生物科技有限公司