Adhesive bandage film, adhesive bandage and preparation method of adhesive bandage film

A band-aid and film-forming technology, which can be used in pharmaceutical formulations, medical preparations with inactive ingredients, and digestive systems, etc., and can solve problems such as oral hygiene effects, residual hazards, and absence of market costs.

Pending Publication Date: 2021-10-19
BEIJING PAISHENG BIOTECH CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The biggest disadvantage of this technology is that many chemicals are used in the preparation process of the product. As cross-linking or intermediate monomers, the residue of these substances is harmful to some extent.
Moreover, the technology has a three-layer structure, the process is too cumbersome, and there i

Method used

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  • Adhesive bandage film, adhesive bandage and preparation method of adhesive bandage film
  • Adhesive bandage film, adhesive bandage and preparation method of adhesive bandage film
  • Adhesive bandage film, adhesive bandage and preparation method of adhesive bandage film

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0039] Example 1

[0040] Step, prepared a film solution:

[0041] According to a percentage of 3 wt%, 10 wt%, weighing hydroxyethyl cellulose (Shandong Jurong Biological Industry Co., Ltd.) 3 g, glycerol 10 g, stir well, add water to 100 g, 60 ° C water bath Stirring is evenly clear and transparent solution, and stands back for use.

[0042] Step two cross-linking film formation:

[0043] Use the bottom area of ​​40 cm 2 , Thickness 2 cm, rectangular stainless steel mold, take a proper amount of film film film, scraping, drying at 45 ° C, physically crosslinking film formation. 50 g, 100 g of film forming solution was added, and the film thickness was adjusted by controlling different additions, and 1 mM, 2 mm film was prepared. Dry film, colorless and transparent, viscous gel film, press the hand press, the surface is very soft, after the pressure is removed, the original state can be restored, invisible.

[0044] Step three to prepare a short side folding creation post:

[0045...

Example Embodiment

[0060] Example 2

[0061] Step, prepared a film solution:

[0062] According to the percentage of 2 wt%, 5 wt%, weighing hydroxyethyl cellulose (Shandong Jurong Biological Industry Co., Ltd.) 2G, glycerol 5 g, stir well, add 10% functional accessories of HEC content Collagen 0.2 g, water to 100 g, 60 ° C, mix well, mix evenly micro-yellow clarified and clear solution, and stand for use.

[0063] Step two cross-linking film formation:

[0064] Use the bottom area of ​​40 cm 2 , Thickness 2 cm, rectangular stainless steel mold, appropriate amount of film film, shaved, flat, 45 ° C, and physically crosslinking film formation. Dry film, micro-yellow transparent, viscous glue film. Compared with the film in Example 1, the 2: 5 proportion of film is hard, but still soft, invisible after the force. The main cause of the product is yellowed, the collagen is added, and the heat-containing collagen contains heat.

[0065] Step three to prepare a short side folding creation post:

[0066] Af...

Example Embodiment

[0080] Example 3

[0081] Step, prepared a film solution:

[0082] Follow the mass ratio of 10: 1 ratio, HEC and carboxymethylcellulose (Shanghai Changguang Enterprise Development Co., Ltd.), mixed into a uniform solid component A. According to the percentage of 2 wt%, 10 wt%, Take the A component 2 g, glycerol 10 g, uniformly mix water to 100 g, 60 ° C, stir well, mix evenly, the micro-yellow clarified and transparent solution, and stand after standing.

[0083] Step two cross-linking film formation:

[0084] Use the bottom area of ​​40 cm 2 , Thickness 2 cm, rectangular stainless steel mold, apply a proper amount of film film, shaved, dry at 70 ° C, and physically crosslinking film formation. Dry film, colorless and transparent, viscous, and soft. In contrast to the film in the first embodiment, the hardness is greater, and the force is invisible after the force.

[0085] Step three to prepare a short side folding creation post:

[0086] After the film was removed, it was cut in...

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PUM

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Abstract

The invention relates to an adhesive bandage film, an adhesive bandage and a preparation method thereof. The adhesive bandage film is prepared through the following method including the steps that by taking the weight of an obtained film forming solution as 100%, 0.1 wt%-10 wt% of cellulose, 5 wt%-40 wt% of an oil-soluble solvent, 0 wt%-1 wt% of auxiliary materials and the balance water are mixed to be uniform, then heating and stirring are conducted, and the film forming solution is obtained; the auxiliary materials comprise one or more of collagen, an anti-inflammatory drug component, a preservative and vitamins; and the obtained film forming solution is dried to obtain the adhesive bandage. The obtained film has good viscosity and degradability.

Description

technical field [0001] The invention relates to a wound dressing film, a wound dressing and a preparation method thereof. Background technique [0002] At present, the wound plasters on the market are rarely used on oral wounds, mainly due to their stickiness, and the edible problem after degradation cannot be solved. There are hundreds of types of band-aids in the band-aid market, but more than 90% are used for wound protection on the skin surface. Others are used for human implantability, which cannot solve the above two problems. In recent years, it has emerged that oral ulcer patches can be effectively used on oral wounds, but the problems of stickiness and degradation have not been well resolved. [0003] CN201710945245.5 provides an adhesive film for oral ulcers, using polymer film-forming agents (chitosan, hydroxypropyl cellulose, sodium carboxymethyl cellulose, polyvinyl alcohol, sodium alginate, etc.) It acts as a film, and after drying, it needs to be free to re...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/38A61K47/32A61K47/34A61K47/36A61K47/10A61K47/18A61P1/02
CPCA61K9/7007A61K47/38A61K47/32A61K47/34A61K47/36A61K47/10A61K47/18A61P1/02
Inventor 张自强符斌徐荣荣郭慧敏王兆丽辛介夫
Owner BEIJING PAISHENG BIOTECH CO LTD
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