Toothpaste composition
A composition and toothpaste technology, applied in dentistry, medical science, oral care and other directions, can solve the problems of inability to produce synergistic effect, reduced stability over time at high temperature, difficult phase separation of hydrogen peroxide, etc., and achieve excellent use feeling and stability. properties, excellent whitening effect, excellent cleaning effect
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[0090] Preservatives are used to prevent microbial contamination that may occur during the preparation and use of the oral composition and to help the long-term preservation of the toothpaste, and sodium benzoate or parabens and the like can be used.
[0091] As another aspect of the present invention, the present invention provides a toothpaste composition as a toothpaste composition comprising a phosphate-containing chelating agent and silicon dioxide, wherein the chelating agent is supersaturated to precipitate phosphate, and the phosphate is precipitated The content of the phosphate is more than 2%, specifically 2 to 10%, based on the total weight of the toothpaste composition.
[0092] The "precipitated phosphate" in the present invention refers to the phosphate added to the composition based on the maximum solubility of the solvent, especially water, based on 25°C. When the solvent is water, the water content can be obtained by known in the art. Water content measurement...
Embodiment 1 to 4 and comparative example 1 to 4
[0140] The toothpaste compositions of Examples 1 to 4 and Comparative Examples 1 to 4 were made from the ingredients and composition ratios shown in Table 1 below.
[0141] Specifically, after pre-dispersing structuring agents (carrageenan, carbomer) and thickeners (poloxamer, xanthan gum) in humectants (PEG, glycerin, etc.) (sodium fluoride, saccharin, etc.) those dissolved or dispersed in purified water, hydrated while stirring. Silica (silica for grinding, silica for thickening) was dispersed and mixed therein, followed by stirring for 20 minutes. Afterwards, a foaming agent (SLS, etc.) was added and stirred under vacuum for 20 minutes. The incense was added, followed by vacuum stirring for 20 minutes to make a toothpaste composition. However, the toothpaste composition of the invention of the present application is not limited to the above-mentioned preparation method.
[0142] [Table 1]
[0143]
experiment example 1
[0144] Experimental example 1. Measuring the physical properties of toothpaste
[0145] (1) Viscosity measurement method
[0146] Viscosity was measured at 25°C with a viscometer (Brookfield RVF) at 20 rpm with a No. 7 Spindle bar.
[0147] (2) Tube suitability measurement method
[0148] The ability of the toothpaste composition to be poured into a typical toothpaste tube was evaluated.
[0149] (3) Solubility measurement method
[0150] 1) Consumer evaluation measurement method for solubility
[0151]It is a method in which the slurry is made by oneself, stirred for a certain period of time, and the degree of solubility is directly evaluated by the consumer. 12 adults were used as objects, and after brushing their teeth with 1 cm of the toothpaste of Examples 1 to 4 and Comparative Examples 1 to 4, Recorded on a 5-point scale: 5 points for very excellent solubility, 4 points for excellent solubility, 3 points for general, 2 points for slightly insufficient solubility, an...
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