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Composition containing p-hydroxyacetophenone as well as preparation method and application thereof

A technology of p-hydroxyacetophenone and composition, applied in the field of preservatives, to achieve the effects of wide antibacterial spectrum, outstanding antiseptic effect, and convenient use

Pending Publication Date: 2021-11-23
益盛汉参化妆品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

How to use it to develop a safe, efficient and easy-to-use cosmetic antibacterial agent has not been studied yet

Method used

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  • Composition containing p-hydroxyacetophenone as well as preparation method and application thereof
  • Composition containing p-hydroxyacetophenone as well as preparation method and application thereof
  • Composition containing p-hydroxyacetophenone as well as preparation method and application thereof

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preparation example Construction

[0024] The invention also provides a preparation method of the composition, which includes the following steps: firstly mixing p-hydroxyacetophenone and C3-C8 dihydric alcohol, then adding plant extracts, and obtaining the finished product after mixing.

[0025] In the present invention, the temperature when the p-hydroxyacetophenone is mixed with the C3-C8 glycol is preferably 60-80°C, more preferably 65-75°C, and even more preferably 70°C.

[0026] In the present invention, the temperature during mixing after adding the plant extract is preferably 40-50°C, more preferably 43-47°C, even more preferably 45°C.

[0027] The invention also provides the application of the composition as a cosmetic preservative.

[0028] In the present invention, the composition can inhibit Candida albicans, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa or Aspergillus niger.

[0029] In the present invention, the pH value of the cosmetic is preferably 3.0-9.0, more preferably 5.0...

Embodiment 1

[0033] The determination of embodiment 1 p-hydroxyacetophenone addition amount

[0034] The solubility of p-hydroxyacetophenone is slightly soluble in water, easily soluble in ethanol, etc., in order to make p-hydroxyacetophenone realize the maximum solubility in the antiseptic composition, other solvents other than water are screened as p-hydroxyacetophenone Solvent, the p-hydroxyacetophenone is made into a liquid use form, which solves the problem of inconvenient operation during the use of p-hydroxyacetophenone.

[0035] Solvents often used as cosmetic solvents include dipropylene glycol, 1.3-butanediol, ethanol, 1,3-propanediol, etc. On the one hand, considering the bad smell of ethanol and its potential impact on product consistency, on the other hand, considering the price of raw materials, dipropylene glycol was initially screened as a solvent for dissolving p-hydroxyacetophenone.

[0036] Preparation method: add p-hydroxyacetophenone and dipropylene glycol in differen...

Embodiment 2

[0043] According to 30 parts of p-hydroxyacetophenone, 30 parts of 1,2-hexanediol, 38 parts of dipropylene glycol, 0.2 parts of Sophora flavescens root extract, 0.6 parts of lilac flower extract, 0.6 parts of grapefruit fruit extract, The weight part of 0.6 part of orange fruit extract weighs raw materials.

[0044] Heat and stir p-hydroxyacetophenone and dipropylene glycol at 70°C to dissolve, add 1,2-hexanediol with stirring at 40°C, and add plant extracts with stirring at 45°C to obtain The preservative of p-hydroxyacetophenone has a pH of 4.67, and the preservative containing p-hydroxyacetophenone has stable properties.

[0045] 1.5wt% of the preservative containing p-hydroxyacetophenone can be added to cream cosmetics, the pH of the cream cosmetics is 4.67, and the properties of the cream cosmetics are stable.

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Abstract

The invention relates to the technical field of preservatives and provides a composition containing p-hydroxyacetophenone as well as a preparation method and application thereof. The composition is prepared from the following components in parts by weight: 10 to 40 parts of the p-hydroxyacetophenone, 30 to 70 parts of C3-C8 dihydric alcohol and 1 to 6 parts of plant extract. A preservative prepared by adopting the composition provided by the invention is safe and efficient, has a wide antibacterial spectrum and good water solubility and is convenient to use. The preservative can be used as an anticorrosion system in a cosmetic formula independently and also can be matched with a traditional preservative to use, so that the dosage of the traditional preservative is reduced. The preservative can also be used as an additive-free raw material in concept and is independently applied to a product, and the anticorrosion effect is good. Meanwhile, harmful substances including formaldehyde and the like are not released in various cosmetics, and the composition is moderate and does not irritate skin.

Description

technical field [0001] The invention relates to the technical field of preservatives, in particular to a composition containing p-hydroxyacetophenone and its preparation method and application. Background technique [0002] In recent years, the natural raw materials and various functional additives used in the cosmetics industry are increasing day by day, and the products are more likely to be eroded by microorganisms. More and more attention has been paid to antiseptic cosmetics, and preservatives have become an indispensable part of cosmetics. The safety of some traditional preservatives in the catalog of preservatives is always controversial. For example, formaldehyde and its sustained-release substances, isothiazolinones, paraben esters, IPBC, triclosan, etc. are often pushed to the forefront of public opinion, making consumers' resistance to preservatives remain high. Manufacturers have less and less choice. Consumers are also increasingly recognizing products with co...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/34A61K8/35A61Q19/00
CPCA61K8/9789A61K8/345A61K8/35A61Q19/00A61K2800/524
Inventor 佟月姣
Owner 益盛汉参化妆品有限公司
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