Method for efficiently preparing beta-aminopropionic acid
A technology of aminopropionic acid and liquid ammonia, applied in chemical instruments and methods, preparation of cyanide reaction, preparation of organic compounds, etc., can solve problems such as low yield and selectivity, and lack of conditions for large-scale use, and achieve The effect of simple purification, high product index and improved economic benefit
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0018] Put acrylonitrile, liquid ammonia, water, isopropanol, piperazine, and ammonium carbonate into the autoclave, wherein the molar ratio of acrylonitrile and liquid ammonia is 1:10, and the addition amounts of water and isopropanol are respectively acrylonitrile The mass is 4 times and 7 times, and the addition amount of piperazine and ammonium carbonate (the molar ratio of the two is: 1:8) is 70 mol% based on acrylonitrile.
[0019] After sealing the reactor, control the reaction temperature to 190° C. and the pressure to 4.8 MPa, and react at constant temperature for 13 hours. After the reaction is completed, a sample is taken to detect that the conversion rate of acrylonitrile is greater than 99%, the ammonia absorption pump is turned on to absorb the remaining ammonia, and then the reaction mother liquor is concentrated under reduced pressure. The concentrated reaction solution is cooled to crystallize, the obtained crystal is suction filtered and dried to obtain the p...
Embodiment 2
[0021] Put acrylonitrile, liquid ammonia, water, tert-butanol, morpholine, and ammonium carbonate into the autoclave, wherein the molar ratio of acrylonitrile and liquid ammonia is 1:8, and the addition amounts of water and tert-butanol are respectively The mass is 6 times and 10 times, and the addition amount of morpholine and ammonium carbonate (the molar ratio of the two is: 1:10) is 90 mol% based on acrylonitrile.
[0022] After sealing the reactor, control the reaction temperature to 250° C. and the pressure to 7.5 MPa, and react at constant temperature for 18 hours. After the reaction is completed, a sample is taken to detect that the conversion rate of acrylonitrile is greater than 99%, the ammonia absorption pump is turned on to absorb the remaining ammonia, and then the reaction mother liquor is concentrated under reduced pressure. The concentrated reaction solution is cooled to crystallize, the obtained crystal is suction filtered and dried to obtain the product, and...
Embodiment 3
[0024] Put acrylonitrile, liquid ammonia, water, isopropanol, diphenylamine and ammonium bicarbonate into the autoclave, wherein the molar ratio of acrylonitrile and liquid ammonia is 1:12, and the addition amount of water and isopropanol is propylene The mass of nitrile is 3 times and 5 times, and the addition amount of diphenylamine and ammonium bicarbonate (the molar ratio of both is: 1:15) is 100 mol% based on acrylonitrile.
[0025] After sealing the reactor, control the reaction temperature to 120° C. and the pressure to 2.3 MPa, and react at constant temperature for 15 hours. After the reaction is completed, a sample is taken to detect that the conversion rate of acrylonitrile is greater than 99%, the ammonia absorption pump is turned on to absorb the remaining ammonia, and then the reaction mother liquor is concentrated under reduced pressure. The concentrated reaction solution is cooled to crystallize, the obtained crystal is suction filtered and dried to obtain the p...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More