Negative liquid crystal composition containing dibenzofuran compound and application thereof
A dibenzofuran, negative liquid crystal technology, applied in liquid crystal materials, nonlinear optics, chemical instruments and methods, etc., to achieve the effects of good low temperature mutual solubility, wide applicability, and shortened response time
- Application Information
AI Technical Summary
Problems solved by technology
 Embodiment 1: the synthesis of compound LDT-1
 (1) Synthesis of LDT-1-2
 Add 150ml THF into a 500ml reaction flask, under nitrogen protection, add 23.8g LDT-1-1, 150ml tetrahydrofuran to the reaction flask, add 0.15mol n-butyllithium n-hexane solution dropwise at -70~-80℃, drop After completing the temperature control reaction for 1 hour, 28.2 g of triisopropyl borate was added dropwise under temperature control at -60 to -70 °C, kept for 1 h, and then returned to -20 °C naturally. Add 400ml of 2M hydrochloric acid aqueous solution for acidification, carry out conventional post-treatment, and recrystallize petroleum ether to obtain light yellow solid compound LDT-1-1, weight 24g, HPLC: 99.8%, yield: 85%.
 (2) Synthesis of LDT-1-4
 Add 28g LDT-1-2, DMF 100ml, water 50ml, anhydrous potassium carbonate 27.6g, LDT-1-332g, tetrakistriphenylphosphine palladium 0.5g into a 500ml reaction bottle, heat up to 70°C for 4h, then use ace...
 Embodiment 2: the synthesis of LDT-2
 (1) Synthesis of LDT-2-2
 Add 150ml of THF to a 500ml reaction flask, under the protection of nitrogen, add 28.2g, 150ml of tetrahydrofuran to the reaction flask, add 0.15mol of n-butyllithium n-hexane solution dropwise at -70~-80°C under temperature control, and complete the temperature control reaction 1 28.2 g of triisopropyl borate was added dropwise at -60 to -70°C under temperature control, kept for 1 hour, and then returned to -20°C naturally. Add 400ml of 2M hydrochloric acid aqueous solution for acidification, perform conventional post-treatment, and recrystallize petroleum ether to obtain light yellow solid compound LDT-1-1, weight 27.1g, HPLC: 99.8%, yield: 83%.
 (2) Synthesis of LDT-2-3
 Add 32.6g of LDT-2-1, 100ml of DMF, 50ml of water, 27.6g of anhydrous potassium carbonate, 32g of LDT-1-2, 0.5g of palladium tetrakistriphenylphosphine into a 500ml reaction bottle, heat up t...
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction