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Traditional Chinese medicine composition for treating reflux esophagitis and application thereof

A technique for reflux esophagitis and composition, which is applied in directions such as drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve problems such as inability to cure recurrence rate and the like

Inactive Publication Date: 2022-03-08
董秀娟 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Current treatment is incurable and the recurrence rate is high

Method used

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  • Traditional Chinese medicine composition for treating reflux esophagitis and application thereof
  • Traditional Chinese medicine composition for treating reflux esophagitis and application thereof
  • Traditional Chinese medicine composition for treating reflux esophagitis and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The formula of traditional Chinese medicine composition for the treatment of reflux esophagitis: Bupleurum 10g, Scutellaria baicalensis 15g, Pinellia 15g, Magnolia officinalis 15g, Chenpi 10g, Poria cocos 30g, perilla stalk 15g, dandelion 30g, sea octopus 30g, agarwood 3g, Atractylodes macrocephala 15g, ginger 10g, red dates 10g.

[0016] Decoction: Weigh out each component according to the above formula components, except agarwood that is ground into powder, add water to the other components until the crude drug is covered, soak for 30 minutes, turn to high heat and boil, after boiling, turn to low heat and cook for 20-30 minutes, fry Take 150ml of medicine juice, decoct each medicine twice, mix the two times of medicine juice to 300ml, add agarwood powder and stir to get it.

Embodiment 2

[0018] The formula of traditional Chinese medicine composition for treating reflux esophagitis: Bupleurum 8g, Scutellaria baicalensis 18g, Pinellia 13g, Magnolia officinalis 18g, Chenpi 12g, Poria cocos 25g, perilla stalk 18g, dandelion 35g, sea octopus 25g, agarwood 4g, Atractylodes macrocephala 18g, ginger 12g, red dates 8g. The decocting method is consistent with embodiment 1.

Embodiment 3

[0020] The formula of traditional Chinese medicine composition for treating reflux esophagitis: Bupleurum 12g, Scutellaria baicalensis 13g, Pinellia 18g, Magnolia officinalis 13g, Tangerine peel 8g, Poria cocos 35g, perilla stalk 13g, dandelion 25g, sea octopus 35g, agarwood 2g, Atractylodes macrocephala 13g, ginger 8g, red dates 12g. The decocting method is consistent with embodiment 1.

[0021] 1. Basic clinical information

[0022] A total of 80 cases of reflux esophagitis patients with liver-stomach stagnation-heat type that met the diagnosis and inclusion criteria were collected. After being eliminated according to the exclusion criteria, there were a total of 75 effective cases, including 36 males and 39 females. Age range: 18 to 70 years old.

[0023] 2. Clinical manifestations of the disease

[0024] ①Typical clinical symptoms: heartburn and regurgitation.

[0025] ② Atypical clinical symptoms: chest pain, burning sensation in upper abdomen, upper abdominal pain, b...

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Abstract

The invention provides a traditional Chinese medicine composition for treating reflux esophagitis and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 8-12 g of radix bupleuri, 13-18 g of radix scutellariae, 13-18 g of rhizoma pinellinae praeparata, 13-18 g of cortex magnoliae officinalis, 8-12 g of pericarpium citri reticulatae, 25-35 g of poria cocos, 13-18 g of perilla stem, 25-35 g of dandelion, 25-35 g of cuttlebone, 2-4 g of agilawood, 13-18 g of rhizoma atractylodis macrocephalae, 8-12 g of fresh ginger and 8-12 g of red dates. In the formula, radix bupleuri, radix scutellariae, rhizoma pinellinae praeparata, cortex magnoliae officinalis and pericarpium citri reticulatae are monarch drugs and have the effects of soothing liver-qi stagnation, clearing heat, calming adverse-rising energy and reducing phlegm; cuttlebone, perilla stem, dandelion, agilawood and poria cocos are used as ministerial drugs and have the effects of tonifying spleen, regulating qi, clearing heat, harmonizing stomach, calming adverse-rising energy, relieving hyperacidity and relieving pain; rhizoma atractylodis macrocephalae, ginger and red dates are used as adjuvant drugs and have the effects of invigorating spleen, replenishing qi and harmonizing stomach; the traditional Chinese medicine formula closely focuses on the pathogenesis of stagnated heat in liver and stomach, can remove heat in liver and stomach due to cold and cool nature, can recover abnormal qi activity due to heavy qi circulation, can strengthen spleen and stomach to increase healthy qi of a human body, achieves the effects of soothing liver and clearing heat, depressing qi and harmonizing stomach, and has a good curative effect on treating reflux esophagitis.

Description

technical field [0001] The invention relates to the field of drugs for treating reflux esophagitis, in particular to a traditional Chinese medicine composition for treating reflux esophagitis and its application. Background technique [0002] Reflux esophagitis is one of the important factors that endanger the health of human digestive tract, and its prevention and treatment is a complicated and lengthy process. Reflux esophagitis (RE) is a common disease of the digestive system worldwide. It is an inflammatory lesion of the esophagus mainly caused by reflux of gastrointestinal contents into the esophagus. Endoscopically, it manifests as esophageal erosion or ulcer. Clinically, heartburn and reflux are the typical symptoms. Some patients may present with non-cardiac chest pain, epigastric burning sensation, belching and other atypical symptoms. In addition, it may be accompanied by a series of extraesophageal symptoms, such as cough, asthma, throat discomfort, etc. . Accor...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/04A61K35/618
CPCA61K36/233A61K36/539A61K36/8888A61K36/575A61K36/752A61K36/076A61K36/535A61K36/288A61K35/618A61K36/835A61K36/284A61K36/9068A61K36/725A61P1/04A61K2300/00
Inventor 董秀娟王立春王定国林天东邢益涛林学英吴维炎陈思瑜
Owner 董秀娟