Method for noninvasive detection of amino acid content of skin and appendage organs thereof and application thereof

An amino acid and skin technology, applied in the field of daily chemical analysis and detection, can solve the problem of no significant impact on amino acid content

Pending Publication Date: 2022-03-22
SHANGHAI JAHWA UNITED
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

I. Horii et al., Stratum corneum hydration and amino acid content in xerotic skin disclose that skin care products containing conventional moistu

Method used

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  • Method for noninvasive detection of amino acid content of skin and appendage organs thereof and application thereof
  • Method for noninvasive detection of amino acid content of skin and appendage organs thereof and application thereof
  • Method for noninvasive detection of amino acid content of skin and appendage organs thereof and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0077] Example 1: Human skin amino acid autofluorescence test

[0078] Eight healthy female volunteers (average age 34.5±3.4 years old) aged 30-40 years old with no visible blood vessels, scars, lichenification or other skin abnormalities on the palm side of the upper arm were tested for amino acid autofluorescence on the skin surface. It is MAXAM tremella pearl nourishing cream, purchased by Shanghai Jahwa United Co., Ltd.

[0079] After signing the informed consent form, the volunteers were screened according to the inclusion and exclusion criteria. Volunteers who met the criteria cleaned the inner skin of the upper arms on both sides with warm water, patted them dry with paper towels, and entered a constant temperature and humidity room (test temperature 21°C ± 1°C , Test humidity 50% ± 5%), sit and rest for 30 minutes. Volunteers kept sitting, and marked 2cm*4cm test area on the palm side skin of the upper arm 15cm above the elbow crease on both sides, one on the left and...

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Abstract

The invention discloses a method for in vivo non-invasive detection of amino acid content of human or animal skin and/or accessory organs thereof, comprising: a) providing a detection device comprising: i) a fluorescence spectrometer/fluorospectrophotometer comprising a light source, an excitation monochromator, an emission monochromator, a detector, and a data processing and instrument control unit. The light transmission range of the Y-shaped optical fiber is 260-2200nm, the light transmission range of the special light path is 200-1100nm, and b) detecting the skin to be detected and/or the affiliated organ part of the skin to be detected to obtain the fluorescence spectrum data of the amino acid of the skin to be detected and/or the affiliated organ part of the skin to be detected and/or the affiliated organ part of the skin to be detected to obtain the fluorescence spectrum data of the amino acid of the skin to be detected and/or the affiliated organ part of the skin to be detected. The invention also provides a method for in-vivo non-invasive evaluation of the nourishing efficacy of cosmetics.

Description

technical field [0001] The invention relates to the field of daily chemical analysis and detection, and more specifically relates to a method for non-invasive detection of amino acid content in skin and / or its accessory organs and its application in the evaluation of cosmetic nourishing efficacy. Background technique [0002] Amino acid is the basic unit of protein required for nutrition. It has special physiological effects on organisms, participates in many metabolic processes, and is also an important indicator to measure the nutritional value of exogenous substances. [0003] As far as the skin is concerned, amino acids are the main components of the natural moisturizing factor (NMF), accounting for more than 40%, and the natural moisturizing factor accounts for 20% to 30% of the dry mass of the stratum corneum, which is important for maintaining normal keratinization cycle, It is of great significance to maintain tissue flexibility and hydration capacity, maintain a sta...

Claims

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Application Information

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IPC IPC(8): G01N21/64A61B5/00
CPCG01N21/6402A61B5/0071A61B5/441A61B5/442
Inventor 周滢袁登峰蒋莉莉贾海东
Owner SHANGHAI JAHWA UNITED
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