Human povidone iodine solution and preparation method thereof

Abstract

The invention discloses a human povidone-iodine solution, which is prepared by the following formula: 5 to 10 kg of povidone-iodine, 0.5 to 1.0 kg of potassium iodide, 6 to 10 kg of betaine, 0.2 to 0.5 kg of D-panthenol, 30 to 65 kg of water and the balance of glycerol, and the total volume of the solution is 100 L. The preparation method comprises the following steps: dissolving, mixing and the like in a corrosion-resistant reaction kettle in corrosion-resistant stirring equipment at a certain stirring speed step by step. The human povidone-iodine solution is scientific and reasonable in formula composition and unique in process, has the effects of promoting wound healing and moistening skin, contains 0.5%-1.0% of effective iodine, can sterilize and disinfect for a long time, kills pathogenic enterobacteria, pyogenic coccus, pathogenic saccharomycetes and other common pathogenic bacteria, prevents secondary infection, resists bacteria and relieves itching, and is a human povidone-iodine solution which is used for people and has the effects of promoting wound healing and moistening skin. When in use, the liquid does not dye clothes, is non-toxic in mouth, does not irritate skin, wounds, mucous membranes and eyes, and does not leave scars after the wounds are healed.

Description

technical field [0001] The invention relates to the technical field of disinfectant preparations, in particular to a preparation method of povidone-iodine disinfectant for humans. Background technique [0002] Bumps and bumps are unavoidable in life, and wounds are prone to infection if they are not treated in time; eczema, allergies, and oral ulcers plague many people; athlete's foot, onychomycosis, and itchy skin affect healthy life; the elderly have cracked skin on their hands and feet, long-term bed rest, and long-term bed sores. When encountering these problems, people often apply some alcohol-containing potions, which are highly irritating; the use of band-aids has poor air permeability; the sterilization is not thorough enough to cause skin infections; even some drugs contain hormones, which can cause more damage if abused. [0003] Povidone-iodine is a complex of polyvinylpyrrolidone-K30 (PVP-K30) and iodine, with active iodine as the main bactericidal component, it ...

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Problems solved by technology

[0013] Invention CN03131706.5 has been disclosed. The invention adds Tween 80 and propylene glycol to increase the dispersion and has a suitable viscosity. Tests have proved that the composition of the formula can only maintain short-term stability, and the pH will be less than 3.5 after more than 6 months, and the pH value is too low, which will also affect the stability of the available iodine content

[0014] Invention CN201810012624.3 has been disclosed. The addition of chitosan in this invention can only enhance the slow-release effect, but cannot achieve the effect of buffering the pH. The invention also adds acetic acid to adjust the pH of the invention to 3.5-4.5. When the wound is ulcerated, it is still irritating to the skin, and acute eye irritation has mild to irritating damage

[0015] The disclosed invention CN202110571717.1 is applied to animals, the pH is adjusted, and the corresponding thickener is used to increase the adhesion, but the thickener used in this invention is hydroxypropyl methylcellulose, although it has a certain viscosity Consistency, but the moisturizing performance is not as good as glycerin. The solution with high content of 10% available iodine is too viscous. With the storage time prolonging, the granular feeling of hydroxypropyl methylcellulose will appear. After dilution, it will become a polydimensional solution with 1% available iodine. The moisturizing performance of ketone-iodine solution is also greatly reduced, and if sodium tripolyphosphate is used as a regulator in the formula adding glycerin, adding a small amount of sodium tripolyphosphate will greatly reduce the viscosity of the product, which will affect the use of the product

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