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Bioactive wound gel and preparation method thereof

A technology of bioactive and bioactive glass, which is applied in the field of bioactive wound gel and its preparation, can solve the problems of slow medical treatment, inability to effectively relieve pain of patients, and long course of treatment, so as to achieve good safety and reliability, and accelerate wound healing. Effects of healing and promoting granulation growth

Pending Publication Date: 2022-04-12
白绍静
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The embodiment of the present invention provides a bioactive wound gel, which aims to solve the problem of slow medical effect and long course of treatment for wounds such as burns, ulcers, bedsores and unhealed wounds caused by unknown reasons in the existing dressings for treating wounds. Can not effectively relieve the pain of the patient

Method used

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Examples

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Effect test

preparation example Construction

[0023] The embodiment of the present invention also provides a preparation method of bioactive wound gel, comprising:

[0024] Weigh each raw material according to the formula of the bioactive wound gel, and set aside;

[0025] Put the vaseline in a constant temperature drying oven for heating and drying for 15-45 minutes at a heating temperature of 100-150°C, and set aside;

[0026] Sieve the bioactive glass with a medicine sieve until the particle size is not greater than 180 μm, pour it into the vaseline in the molten state, stir and mix evenly to obtain a mixture;

[0027] The mixture is uniformly mixed with sodium hyaluronate for 15-45 minutes, and then heat-preserved and packaged to obtain the product.

[0028] In a preferred embodiment of the present invention, the petroleum jelly is placed in a constant temperature drying oven for heating and drying for 20 minutes at a heating temperature of 100° C., and is ready for use.

[0029] In a preferred embodiment of the pre...

Embodiment 1

[0032] Bioactive wound gel, including the following raw materials in mass percentage: 0.5% sodium hyaluronate, 24.5% bioactive glass and 75% medical petrolatum. Among them, the bioactive glass includes the following raw materials in mass percentage: 43% silicon dioxide, 25% sodium oxide, 26% calcium oxide and 6% phosphorus pentoxide.

[0033] Weigh each raw material according to the above formula of bioactive wound gel, and set aside; place medical vaseline in a constant temperature drying oven for heating and drying for 20 minutes at a heating temperature of 100°C, set aside; break the bioactive glass, and use a drug sieve After sieving until the particle size is not greater than 180 μm, pour it into the medical vaseline in a molten state, stir and mix uniformly to obtain a mixture; uniformly mix the mixture with sodium hyaluronate for 30 minutes, and then heat-preserve and package it to obtain .

Embodiment 2

[0035] Bioactive wound gel, including the following raw materials in mass percentage: sodium hyaluronate 2%, bioactive glass 25%, and medical petrolatum 73%. Among them, bioactive glass includes the following raw materials in mass percentage: 40% silicon dioxide, 27% sodium oxide, 27% calcium oxide and 6% phosphorus pentoxide.

[0036] Weigh each raw material according to the above formula of bioactive wound gel, and set aside; place medical vaseline in a constant temperature drying oven for heating and drying for 20 minutes at a heating temperature of 100°C, set aside; break the bioactive glass, and use a drug sieve After sieving until the particle size is not greater than 180 μm, pour it into the medical vaseline in a molten state, stir and mix uniformly to obtain a mixture; uniformly mix the mixture with sodium hyaluronate for 30 minutes, and then heat-preserve and package it to obtain .

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PUM

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Abstract

The invention is suitable for the technical field of medicines, and provides a bioactive wound gel and a preparation method thereof, and the bioactive wound gel comprises the following raw materials in percentage by mass: 0.2-2% of sodium hyaluronate, 22-25% of bioactive glass and 70-75% of vaseline. The bioactive wound gel provided by the invention is prepared by mixing sodium hyaluronate, bioactive glass and vaseline according to a specific mass ratio, and clinical tests prove that the bioactive wound gel provided by the invention has obvious effects of promoting granulation growth and accelerating wound healing on various general surgery department refractory wounds; and no obvious adverse reaction, anaphylactic reaction and systemic side effect exist, and the safety and the reliability are good.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a bioactive wound gel and a preparation method thereof. Background technique [0002] Trauma is the destruction of human tissues or organs caused by external factors. Any external factors imposed on the human body also include structural or functional damage caused by high temperature, cold, electric current, radiation, acid, alkali, poisonous gas, poisonous insects, mosquito bites, etc. Trauma not only has a high incidence rate, but also varies greatly in degree. Severe trauma can cause systemic reactions, and local manifestations include pain, swelling, and tenderness in the injured area. [0003] However, the existing dressings used to treat wounds cannot absorb wound exudate well to provide a good local environment for wound healing, especially for wounds such as burns, ulcers, decubitus and unhealed wounds caused by unknown reasons. , The course of treatmen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K33/42A61K47/06A61K47/36A61P17/02A61K33/08A61K33/00
Inventor 白绍静
Owner 白绍静
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